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The map label for this gene is rocC [H]

Identifier: 138893844

GI number: 138893844

Start: 179560

End: 180975

Strand: Direct

Name: rocC [H]

Synonym: GTNG_0168

Alternate gene names: 138893844

Gene position: 179560-180975 (Clockwise)

Preceding gene: 138893842

Following gene: 138893845

Centisome position: 5.06

GC content: 51.34

Gene sequence:

>1416_bases
ATGCCACCAGCGCAGGAATTGAAACGAGAGCTAAAAAGTAGACATTTGTTTATGATTGCGCTTGGCGGGGTGATTGGAAC
CGGTTTGTTTTTAGGATCCGGATACACCATTCATGAAGCGGGACCTGGAGGAGCGATTGCCGCCTACTTATTCGGCGGAT
TCGTCATGTATTTGACGATGCTTTCGTTAGGGGAATTGGCTGTGAGGATCCCTGACGCTGGGTCATATCAAACGTATGCG
ACGAAATTCATCTCGCCGGCCGCAGGGTTTTGCATCGGCTGGCTGTCATGGCTCAACTGGTCAGTGACGGTCGGCATTGA
GCTGCTTACAGTCAGCATCCTCATGAAACGCTGGTTCCCTGATGTGCCAACATGGGTGTTTTGCGCTGTCTTCGCCTTGT
TGTTGTTTTTGGTGAACGCCTTGTCTGTCAAAGGTTTCGCTGAGGTGGAGTTTTGGTTTTCGAGCGTGAAGGTGTTGACG
GTCATCGCCTTTATTGTTCTTGGTTTGGCGGCGATGTTCGGCATCGTCCATATGAAAAGCGGACAACCCGCCCCGTTTTT
CTCGAACTTTACAGACCATGGCGGCTTGTTTCCTAATGGGTTTTGGGCGATCTTTACAACGATGATTCTTGTGAATTTCT
CCTTTCAAGGAACGGAATTGGTGGGGGTCGCAGCCGGAGAAAGCCGTGAGCCGGAGAAAACAGTACCGATTGCGTTGCGC
AACACGGTGTGGCGGATTTTGATTTTCTTCGTTTTGGCCATTTTTGTACTTGCTGGTTTGTTTCCATGGGAGAAAGCCGG
TGTTGTGGAAAGCCCGTTTGTCGTGGTATTTGACAATATCGGCATTCCGTATGCGGCCGATATCATGAACTTTGTCATTA
TTACCGCGGTGCTGTCGGTAGCTAACTCAGGATTGTATGCGACGTCACGCGTGCTATGGTCGATGTCGCGCCAAGGCATG
GTTACGCCGTTTTTCAGCAAACTCTCGAAGCGGGGCGTGCCGATCAATGCGCTAATCGCCAGCATTGCCATCGGATGCTT
GTCGTTGCTGTGCAGCGCGTACGCAGAAGATACCGTGTATGTATGGTTGACGGCGATCGCTGGGTTTGGCGCGGTGACTG
TTTGGGCCTCCATCGCGCTGTCGAGCTATTTGGGACGGAAAGCGTTTTTGCGTGAAGGCGGCGATGTGCGCGATTTGAAA
TACCGGACGCCGCTCTATCCGTTCGTACCGCTGGCCGCGTTCATACTGAATATGGCGATAATTGTCGGATTGGCTTTTAT
CCCTGATCAACGGATCGCGCTTTACTGCGGCATTCCATTCTTGCTCGTGTGCTATGCGTATTATCACCTCGTGGCGAAAA
AGCGAATCCATCTTCAACGCACAGAAGAAGAGGTAGAGCTGAAAGCCGCCAAGTAA

Upstream 100 bases:

>100_bases
AAATATGCGAAAAAAAATTTTGCCGGAGAAAAAACGCCGTTTACTTGATAGAAATGTAAGCGGTTGCGAAATCTATAAGT
AGTGGAAGGGAGAGATTTGG

Downstream 100 bases:

>100_bases
GTAAAAATCATTGAAAAAAGCCATAATAATTTGCATAATATAACTATGAAACCGTTTTATTACGAAAAATTTTTTTGCTC
GTGAAAAGGAGGACGACGAA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MPPAQELKRELKSRHLFMIALGGVIGTGLFLGSGYTIHEAGPGGAIAAYLFGGFVMYLTMLSLGELAVRIPDAGSYQTYA
TKFISPAAGFCIGWLSWLNWSVTVGIELLTVSILMKRWFPDVPTWVFCAVFALLLFLVNALSVKGFAEVEFWFSSVKVLT
VIAFIVLGLAAMFGIVHMKSGQPAPFFSNFTDHGGLFPNGFWAIFTTMILVNFSFQGTELVGVAAGESREPEKTVPIALR
NTVWRILIFFVLAIFVLAGLFPWEKAGVVESPFVVVFDNIGIPYAADIMNFVIITAVLSVANSGLYATSRVLWSMSRQGM
VTPFFSKLSKRGVPINALIASIAIGCLSLLCSAYAEDTVYVWLTAIAGFGAVTVWASIALSSYLGRKAFLREGGDVRDLK
YRTPLYPFVPLAAFILNMAIIVGLAFIPDQRIALYCGIPFLLVCYAYYHLVAKKRIHLQRTEEEVELKAAK

Sequences:

>Translated_471_residues
MPPAQELKRELKSRHLFMIALGGVIGTGLFLGSGYTIHEAGPGGAIAAYLFGGFVMYLTMLSLGELAVRIPDAGSYQTYA
TKFISPAAGFCIGWLSWLNWSVTVGIELLTVSILMKRWFPDVPTWVFCAVFALLLFLVNALSVKGFAEVEFWFSSVKVLT
VIAFIVLGLAAMFGIVHMKSGQPAPFFSNFTDHGGLFPNGFWAIFTTMILVNFSFQGTELVGVAAGESREPEKTVPIALR
NTVWRILIFFVLAIFVLAGLFPWEKAGVVESPFVVVFDNIGIPYAADIMNFVIITAVLSVANSGLYATSRVLWSMSRQGM
VTPFFSKLSKRGVPINALIASIAIGCLSLLCSAYAEDTVYVWLTAIAGFGAVTVWASIALSSYLGRKAFLREGGDVRDLK
YRTPLYPFVPLAAFILNMAIIVGLAFIPDQRIALYCGIPFLLVCYAYYHLVAKKRIHLQRTEEEVELKAAK
>Mature_470_residues
PPAQELKRELKSRHLFMIALGGVIGTGLFLGSGYTIHEAGPGGAIAAYLFGGFVMYLTMLSLGELAVRIPDAGSYQTYAT
KFISPAAGFCIGWLSWLNWSVTVGIELLTVSILMKRWFPDVPTWVFCAVFALLLFLVNALSVKGFAEVEFWFSSVKVLTV
IAFIVLGLAAMFGIVHMKSGQPAPFFSNFTDHGGLFPNGFWAIFTTMILVNFSFQGTELVGVAAGESREPEKTVPIALRN
TVWRILIFFVLAIFVLAGLFPWEKAGVVESPFVVVFDNIGIPYAADIMNFVIITAVLSVANSGLYATSRVLWSMSRQGMV
TPFFSKLSKRGVPINALIASIAIGCLSLLCSAYAEDTVYVWLTAIAGFGAVTVWASIALSSYLGRKAFLREGGDVRDLKY
RTPLYPFVPLAAFILNMAIIVGLAFIPDQRIALYCGIPFLLVCYAYYHLVAKKRIHLQRTEEEVELKAAK

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=371, Percent_Identity=23.4501347708895, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI115648022, Length=371, Percent_Identity=23.4501347708895, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI87081708, Length=460, Percent_Identity=49.7826086956522, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1788480, Length=476, Percent_Identity=43.4873949579832, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1786302, Length=450, Percent_Identity=37.1111111111111, Blast_Score=291, Evalue=8e-80,
Organism=Escherichia coli, GI1786789, Length=402, Percent_Identity=39.0547263681592, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI48994972, Length=464, Percent_Identity=35.3448275862069, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1789017, Length=448, Percent_Identity=36.3839285714286, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1786602, Length=465, Percent_Identity=35.2688172043011, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI87081915, Length=407, Percent_Identity=36.1179361179361, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1790653, Length=463, Percent_Identity=33.9092872570194, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI87081869, Length=264, Percent_Identity=29.9242424242424, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082023, Length=387, Percent_Identity=24.5478036175711, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082250, Length=467, Percent_Identity=24.8394004282655, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=361, Percent_Identity=24.6537396121884, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=370, Percent_Identity=22.4324324324324, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=443, Percent_Identity=33.6343115124154, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6320772, Length=443, Percent_Identity=33.8600451467269, Blast_Score=243, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6322892, Length=409, Percent_Identity=33.9853300733496, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=33.5802469135802, Blast_Score=226, Evalue=5e-60,
Organism=Saccharomyces cerevisiae, GI6324059, Length=487, Percent_Identity=32.2381930184805, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320717, Length=419, Percent_Identity=30.3102625298329, Blast_Score=213, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6321629, Length=482, Percent_Identity=28.4232365145228, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320251, Length=416, Percent_Identity=30.5288461538462, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6319824, Length=416, Percent_Identity=29.3269230769231, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6319542, Length=408, Percent_Identity=29.1666666666667, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319543, Length=408, Percent_Identity=29.656862745098, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324990, Length=509, Percent_Identity=29.2730844793713, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6321053, Length=493, Percent_Identity=27.789046653144, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324924, Length=481, Percent_Identity=30.1455301455301, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322967, Length=488, Percent_Identity=28.0737704918033, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6324981, Length=486, Percent_Identity=29.2181069958848, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6319608, Length=442, Percent_Identity=24.4343891402715, Blast_Score=149, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6320364, Length=546, Percent_Identity=23.2600732600733, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24667468, Length=368, Percent_Identity=20.3804347826087, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51601; Mature: 51469

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPAQELKRELKSRHLFMIALGGVIGTGLFLGSGYTIHEAGPGGAIAAYLFGGFVMYLTM
CCCHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
LSLGELAVRIPDAGSYQTYATKFISPAAGFCIGWLSWLNWSVTVGIELLTVSILMKRWFP
HHHHHHEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
DVPTWVFCAVFALLLFLVNALSVKGFAEVEFWFSSVKVLTVIAFIVLGLAAMFGIVHMKS
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GQPAPFFSNFTDHGGLFPNGFWAIFTTMILVNFSFQGTELVGVAAGESREPEKTVPIALR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHH
NTVWRILIFFVLAIFVLAGLFPWEKAGVVESPFVVVFDNIGIPYAADIMNFVIITAVLSV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
ANSGLYATSRVLWSMSRQGMVTPFFSKLSKRGVPINALIASIAIGCLSLLCSAYAEDTVY
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VWLTAIAGFGAVTVWASIALSSYLGRKAFLREGGDVRDLKYRTPLYPFVPLAAFILNMAI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IVGLAFIPDQRIALYCGIPFLLVCYAYYHLVAKKRIHLQRTEEEVELKAAK
HHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure 
PPAQELKRELKSRHLFMIALGGVIGTGLFLGSGYTIHEAGPGGAIAAYLFGGFVMYLTM
CCHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHH
LSLGELAVRIPDAGSYQTYATKFISPAAGFCIGWLSWLNWSVTVGIELLTVSILMKRWFP
HHHHHHEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
DVPTWVFCAVFALLLFLVNALSVKGFAEVEFWFSSVKVLTVIAFIVLGLAAMFGIVHMKS
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GQPAPFFSNFTDHGGLFPNGFWAIFTTMILVNFSFQGTELVGVAAGESREPEKTVPIALR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHH
NTVWRILIFFVLAIFVLAGLFPWEKAGVVESPFVVVFDNIGIPYAADIMNFVIITAVLSV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
ANSGLYATSRVLWSMSRQGMVTPFFSKLSKRGVPINALIASIAIGCLSLLCSAYAEDTVY
HCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
VWLTAIAGFGAVTVWASIALSSYLGRKAFLREGGDVRDLKYRTPLYPFVPLAAFILNMAI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
IVGLAFIPDQRIALYCGIPFLLVCYAYYHLVAKKRIHLQRTEEEVELKAAK
HHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]