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The map label for this gene is mrp [H]

Identifier: 138893820

GI number: 138893820

Start: 146382

End: 147398

Strand: Direct

Name: mrp [H]

Synonym: GTNG_0141

Alternate gene names: 138893820

Gene position: 146382-147398 (Clockwise)

Preceding gene: 138893819

Following gene: 138893822

Centisome position: 4.12

GC content: 48.67

Gene sequence:

>1017_bases
ATGCTGACGGAAAACGACGTGCGAGCCATTCTTGAAAACATGAAAGACCCATTTTTAAACAAAACGTTTAAGGAAACGAA
CGCCATTCAAGAAATTAAAATTAAAGAAGAGAAGAACCATGTCAGCGTAAAAATCGCGCTCGCTAAAATCGGTACTCCTG
ACCAACTCCGCGTACAAACGGCGATCGTCCAACAGTTGAAAGACGCAGGTGCTGCTTCTGTCGGACTGCGGTTTGCCGAA
CTGCCGCGAGAAGTCGTTGAGGAATATAGCGAGAATAAGCAAAGAACGACATATATCGCTATCGCCAGCGGCAAAGGTGG
GGTTGGGAAATCAACCGTTTCTGTCAATTTGGCCGTCGCGCTTGCTCGGCTTGGCAAAAAAGTCGGGTTGATCGACGCTG
ATATTTACGGGTTTAGTGTACCCGACATGATGGGGATCACCGAGCGCCCAACAGTAAGAGGTGATAAGATTATCCCGGTT
GAACGGTTTGGGGTAAAAGTCATTTCGATGGCCTTTTTCGTTGAGGACAACGCTCCGGTTATTTGGCGCGGTCCGATGCT
TGGAAAAATGCTCAACAACTTTTTTAAAGAAGTCGAATGGGGCGATTTAGACTACCTGCTGCTTGACCTGCCGCCAGGTA
CAGGTGACGTCGCTTTAGATGTGCATACGCTTCTGCCGTCATGCAAAGAAATTATCGTTACAACCCCGCATCCAACCGCC
GCGTTTGTCGCTGCCCGTGCCGGGGCCATGGCCTTACGCACTGAACACGAGATTATCGGTGTCATCGAAAATATGTCGTA
TTACGAAAGCCGGAAAACAGGTGAACGGGAATACGTGTTTGGCAAAGGTGGCGGAGCGAAGCTGGCAAAAGAGCTACAAA
CAGAACTGTTAGGGCAGCTGCCGCTTCAGCAACCAGATTGGAATGACGACGATTTTGCTCCGTCCGTTTATGCGGAAGAT
CATCCGATTGGGAAAATTTATATGGATATCGCCCGAAAAATTGCCGCGAAGTATTGA

Upstream 100 bases:

>100_bases
AGTAAATGGGAAAGAAGGCTGAACATGGCGGTTTCCTAGCAACTTATGGTATAGTAGATAATAGAAACAGTCATTGATTG
AAAAAGGGTTGGTGAATACG

Downstream 100 bases:

>100_bases
ACAGCTTAAACATAAAGCGTCCGATGCCTTGAGTCGCTCGCGCTCGTTCCTTTGAGCGTTGGCGAATTTTGGCACACGGA
CGCTTTTTATTCGATTAACC

Product: Mrp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLTENDVRAILENMKDPFLNKTFKETNAIQEIKIKEEKNHVSVKIALAKIGTPDQLRVQTAIVQQLKDAGAASVGLRFAE
LPREVVEEYSENKQRTTYIAIASGKGGVGKSTVSVNLAVALARLGKKVGLIDADIYGFSVPDMMGITERPTVRGDKIIPV
ERFGVKVISMAFFVEDNAPVIWRGPMLGKMLNNFFKEVEWGDLDYLLLDLPPGTGDVALDVHTLLPSCKEIIVTTPHPTA
AFVAARAGAMALRTEHEIIGVIENMSYYESRKTGEREYVFGKGGGAKLAKELQTELLGQLPLQQPDWNDDDFAPSVYAED
HPIGKIYMDIARKIAAKY

Sequences:

>Translated_338_residues
MLTENDVRAILENMKDPFLNKTFKETNAIQEIKIKEEKNHVSVKIALAKIGTPDQLRVQTAIVQQLKDAGAASVGLRFAE
LPREVVEEYSENKQRTTYIAIASGKGGVGKSTVSVNLAVALARLGKKVGLIDADIYGFSVPDMMGITERPTVRGDKIIPV
ERFGVKVISMAFFVEDNAPVIWRGPMLGKMLNNFFKEVEWGDLDYLLLDLPPGTGDVALDVHTLLPSCKEIIVTTPHPTA
AFVAARAGAMALRTEHEIIGVIENMSYYESRKTGEREYVFGKGGGAKLAKELQTELLGQLPLQQPDWNDDDFAPSVYAED
HPIGKIYMDIARKIAAKY
>Mature_338_residues
MLTENDVRAILENMKDPFLNKTFKETNAIQEIKIKEEKNHVSVKIALAKIGTPDQLRVQTAIVQQLKDAGAASVGLRFAE
LPREVVEEYSENKQRTTYIAIASGKGGVGKSTVSVNLAVALARLGKKVGLIDADIYGFSVPDMMGITERPTVRGDKIIPV
ERFGVKVISMAFFVEDNAPVIWRGPMLGKMLNNFFKEVEWGDLDYLLLDLPPGTGDVALDVHTLLPSCKEIIVTTPHPTA
AFVAARAGAMALRTEHEIIGVIENMSYYESRKTGEREYVFGKGGGAKLAKELQTELLGQLPLQQPDWNDDDFAPSVYAED
HPIGKIYMDIARKIAAKY

Specific function: Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=243, Percent_Identity=38.2716049382716, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI6912540, Length=212, Percent_Identity=37.2641509433962, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI118572611, Length=290, Percent_Identity=32.7586206896552, Blast_Score=128, Evalue=6e-30,
Organism=Escherichia coli, GI87082045, Length=339, Percent_Identity=35.3982300884956, Blast_Score=189, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25143050, Length=274, Percent_Identity=35.4014598540146, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322188, Length=214, Percent_Identity=36.4485981308411, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321347, Length=214, Percent_Identity=34.1121495327103, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221511043, Length=195, Percent_Identity=41.025641025641, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24667611, Length=212, Percent_Identity=39.622641509434, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19921440, Length=234, Percent_Identity=38.034188034188, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 37277; Mature: 37277

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTENDVRAILENMKDPFLNKTFKETNAIQEIKIKEEKNHVSVKIALAKIGTPDQLRVQT
CCCCHHHHHHHHHHCCHHHHHHHHHHCCHHEEEEECCCCEEEEEEEEEECCCCHHHHHHH
AIVQQLKDAGAASVGLRFAELPREVVEEYSENKQRTTYIAIASGKGGVGKSTVSVNLAVA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEHHHHHH
LARLGKKVGLIDADIYGFSVPDMMGITERPTVRGDKIIPVERFGVKVISMAFFVEDNAPV
HHHHCCCCCEEECCCCCCCCCHHCCCCCCCCCCCCEECCHHHHCCEEEEEEEEEECCCCE
IWRGPMLGKMLNNFFKEVEWGDLDYLLLDLPPGTGDVALDVHTLLPSCKEIIVTTPHPTA
EEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEHHHHCCCCCEEEEECCCCHH
AFVAARAGAMALRTEHEIIGVIENMSYYESRKTGEREYVFGKGGGAKLAKELQTELLGQL
HHHHHHCCHHEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
PLQQPDWNDDDFAPSVYAEDHPIGKIYMDIARKIAAKY
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTENDVRAILENMKDPFLNKTFKETNAIQEIKIKEEKNHVSVKIALAKIGTPDQLRVQT
CCCCHHHHHHHHHHCCHHHHHHHHHHCCHHEEEEECCCCEEEEEEEEEECCCCHHHHHHH
AIVQQLKDAGAASVGLRFAELPREVVEEYSENKQRTTYIAIASGKGGVGKSTVSVNLAVA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEHHHHHH
LARLGKKVGLIDADIYGFSVPDMMGITERPTVRGDKIIPVERFGVKVISMAFFVEDNAPV
HHHHCCCCCEEECCCCCCCCCHHCCCCCCCCCCCCEECCHHHHCCEEEEEEEEEECCCCE
IWRGPMLGKMLNNFFKEVEWGDLDYLLLDLPPGTGDVALDVHTLLPSCKEIIVTTPHPTA
EEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEHHHHCCCCCEEEEECCCCHH
AFVAARAGAMALRTEHEIIGVIENMSYYESRKTGEREYVFGKGGGAKLAKELQTELLGQL
HHHHHHCCHHEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
PLQQPDWNDDDFAPSVYAEDHPIGKIYMDIARKIAAKY
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7559346; 8969501; 9384377; 2517635 [H]