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The map label for this gene is ectB [H]

Identifier: 13474948

GI number: 13474948

Start: 4807200

End: 4808459

Strand: Direct

Name: ectB [H]

Synonym: mlr5943

Alternate gene names: 13474948

Gene position: 4807200-4808459 (Clockwise)

Preceding gene: 13474942

Following gene: 13474949

Centisome position: 68.32

GC content: 53.33

Gene sequence:

>1260_bases
ATGGATATCGACATTTTCGCAGCCTACGAGTCTAACGTTCGTCGCTATGGACGATCGTTTCCAACAGTCTTTAAAAAGTC
GCTTGGGGCGACAATCTGGGACGAGTCCGGAAAGCCATATATTGATTTCCTTGTAGGGTCAGGCGCGCTCAACTACGGTC
ATAACAACCCGGATATTATTGAACCGGCAATTCAATATCTCGCCGATCAAAATATCGTCTTGTCGCTTGATATGTATACA
GCTGCAAAGCGTGATTTCATCGAAGTGTTTGTCGAGTCGATCCTGAAGCCCCGGGGCCTTTCTTACAAGATACAGTTTCC
TGGGCCGACCGGGACGAACGCTAACGAAGCGGCGTTGGCGCTGGCGCGAAAATATACCGGCCGCTCGAGTGTCATGGCCT
TCACAAATTCGTACCATGGCATGTCGCTCGGCTCCTTGGCGGTGTCGGGTTCAGCGTCAACCAGACAGCTTGGCGGCGTT
GCTCGCCACGATGTGATCCGAGTGCCTTACGAGAACTATCCGAACCAAACTTTCGATTCCGCGAGTTACATTGATCACGT
GTTGGGCGACCCAGGCAGCGGGATCGAAAAGCCGGCCGCAATCATCCTGGAGCCCATCCAGGCAGAAGGCGGCATGAACA
CCGCATCCGCACCATGGCTCTCAGAAATTCAGCGCATTTGCCGTAAGCACGACGTTGTTTTCATCGTCGATGACATTCAG
GCAGGTTCGGGACGAACGGGCGATTTCTTCTCATTCGAGTTCGCGAAAATCGAGCCCGACATCGTGTGTCTTTCGAAATC
GCTAAGCGGTTCAGGTAATCCGTTGTCCATAGTTCTGATTCGCCCCGACATGGACATATGGAATCCGGGGGAACATAGCG
GGACCTTCAGAGGCAATAATCTCGCCTTTGTGACTTCCGCGGCCATGTGCAAAATGTGGTCCGATAGGCAGTTTACTACC
GCCGTCGAGCGGACTGCCGTCAAACTGCAAGAACACCTTGATCGCCTCGTTGCGAAATACCCCAAGTGCATCGAACAAAA
GCGCGGCCGTGGTCTGATGGCCGGCCTCAAGTGCCGTTCACAGGCCGTTGTTGGCCGTGTGCACGATGTCGCGTTCGAAA
ACGGCCTGCTGATCGAATCCTCGGGGCCAAATCGCGACGTCATCAAAGTCCTTCCGCCGATAACCATCTCAGATGACGAA
CTCGATCATGGCATTGCCATCCTCGATCAGGCACTACAGGAGAAAACAAATGGCGATTAA

Upstream 100 bases:

>100_bases
CCGATATTGGCCGAAGACAATCGTCGAAATCAATGGTTTGGAATACGTGAACATAGAACCTGCAGCGTTGACCGCATGCC
GCATACAGAGAGGCCCTTGA

Downstream 100 bases:

>100_bases
TCAAGTAGCTCAAACGCCGGCCATCTCGCCTCTTACGATCAAGGAACGAACCGGCTCGATCAGCACTGCGGAGATGATCT
CGGTCCTGAAAGGAGAGACC

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MDIDIFAAYESNVRRYGRSFPTVFKKSLGATIWDESGKPYIDFLVGSGALNYGHNNPDIIEPAIQYLADQNIVLSLDMYT
AAKRDFIEVFVESILKPRGLSYKIQFPGPTGTNANEAALALARKYTGRSSVMAFTNSYHGMSLGSLAVSGSASTRQLGGV
ARHDVIRVPYENYPNQTFDSASYIDHVLGDPGSGIEKPAAIILEPIQAEGGMNTASAPWLSEIQRICRKHDVVFIVDDIQ
AGSGRTGDFFSFEFAKIEPDIVCLSKSLSGSGNPLSIVLIRPDMDIWNPGEHSGTFRGNNLAFVTSAAMCKMWSDRQFTT
AVERTAVKLQEHLDRLVAKYPKCIEQKRGRGLMAGLKCRSQAVVGRVHDVAFENGLLIESSGPNRDVIKVLPPITISDDE
LDHGIAILDQALQEKTNGD

Sequences:

>Translated_419_residues
MDIDIFAAYESNVRRYGRSFPTVFKKSLGATIWDESGKPYIDFLVGSGALNYGHNNPDIIEPAIQYLADQNIVLSLDMYT
AAKRDFIEVFVESILKPRGLSYKIQFPGPTGTNANEAALALARKYTGRSSVMAFTNSYHGMSLGSLAVSGSASTRQLGGV
ARHDVIRVPYENYPNQTFDSASYIDHVLGDPGSGIEKPAAIILEPIQAEGGMNTASAPWLSEIQRICRKHDVVFIVDDIQ
AGSGRTGDFFSFEFAKIEPDIVCLSKSLSGSGNPLSIVLIRPDMDIWNPGEHSGTFRGNNLAFVTSAAMCKMWSDRQFTT
AVERTAVKLQEHLDRLVAKYPKCIEQKRGRGLMAGLKCRSQAVVGRVHDVAFENGLLIESSGPNRDVIKVLPPITISDDE
LDHGIAILDQALQEKTNGD
>Mature_419_residues
MDIDIFAAYESNVRRYGRSFPTVFKKSLGATIWDESGKPYIDFLVGSGALNYGHNNPDIIEPAIQYLADQNIVLSLDMYT
AAKRDFIEVFVESILKPRGLSYKIQFPGPTGTNANEAALALARKYTGRSSVMAFTNSYHGMSLGSLAVSGSASTRQLGGV
ARHDVIRVPYENYPNQTFDSASYIDHVLGDPGSGIEKPAAIILEPIQAEGGMNTASAPWLSEIQRICRKHDVVFIVDDIQ
AGSGRTGDFFSFEFAKIEPDIVCLSKSLSGSGNPLSIVLIRPDMDIWNPGEHSGTFRGNNLAFVTSAAMCKMWSDRQFTT
AVERTAVKLQEHLDRLVAKYPKCIEQKRGRGLMAGLKCRSQAVVGRVHDVAFENGLLIESSGPNRDVIKVLPPITISDDE
LDHGIAILDQALQEKTNGD

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=425, Percent_Identity=27.0588235294118, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI284507298, Length=318, Percent_Identity=27.6729559748428, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=27.3364485981308, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI37574042, Length=419, Percent_Identity=27.2076372315036, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI13994255, Length=430, Percent_Identity=23.2558139534884, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=27.511961722488, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=27.3869346733668, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI188536080, Length=417, Percent_Identity=21.5827338129496, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679950, Length=417, Percent_Identity=21.5827338129496, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679946, Length=417, Percent_Identity=21.5827338129496, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=28.8095238095238, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=32, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789759, Length=401, Percent_Identity=27.6807980049875, Blast_Score=161, Evalue=9e-41,
Organism=Escherichia coli, GI145693181, Length=393, Percent_Identity=27.4809160305344, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=25.6281407035176, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786991, Length=395, Percent_Identity=24.8101265822785, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1786349, Length=337, Percent_Identity=24.9258160237389, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=407, Percent_Identity=27.2727272727273, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32564660, Length=419, Percent_Identity=27.2076372315036, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25144274, Length=218, Percent_Identity=30.2752293577982, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=433, Percent_Identity=25.1732101616628, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71992977, Length=424, Percent_Identity=23.8207547169811, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=416, Percent_Identity=30.2884615384615, Blast_Score=172, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6324432, Length=413, Percent_Identity=30.0242130750605, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321456, Length=375, Percent_Identity=28.2666666666667, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=24.5222929936306, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357415, Length=404, Percent_Identity=26.7326732673267, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21356575, Length=424, Percent_Identity=25.7075471698113, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=24.1457858769932, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28574759, Length=440, Percent_Identity=24.5454545454545, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281366494, Length=260, Percent_Identity=25, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24667139, Length=260, Percent_Identity=25, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24667143, Length=260, Percent_Identity=25, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 45825; Mature: 45825

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIDIFAAYESNVRRYGRSFPTVFKKSLGATIWDESGKPYIDFLVGSGALNYGHNNPDII
CCEEEEEHHHHHHHHHCCCCHHHHHHHHCCEEECCCCCCEEEEEEECCEEECCCCCCHHH
EPAIQYLADQNIVLSLDMYTAAKRDFIEVFVESILKPRGLSYKIQFPGPTGTNANEAALA
HHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
LARKYTGRSSVMAFTNSYHGMSLGSLAVSGSASTRQLGGVARHDVIRVPYENYPNQTFDS
HHHHHCCCCCEEEEECCCCCCEECCEEECCCCCHHHHCCHHHCCEEECCCCCCCCCCCCH
ASYIDHVLGDPGSGIEKPAAIILEPIQAEGGMNTASAPWLSEIQRICRKHDVVFIVDDIQ
HHHHHHHHCCCCCCCCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCC
AGSGRTGDFFSFEFAKIEPDIVCLSKSLSGSGNPLSIVLIRPDMDIWNPGEHSGTFRGNN
CCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
LAFVTSAAMCKMWSDRQFTTAVERTAVKLQEHLDRLVAKYPKCIEQKRGRGLMAGLKCRS
EEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
QAVVGRVHDVAFENGLLIESSGPNRDVIKVLPPITISDDELDHGIAILDQALQEKTNGD
HHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIDIFAAYESNVRRYGRSFPTVFKKSLGATIWDESGKPYIDFLVGSGALNYGHNNPDII
CCEEEEEHHHHHHHHHCCCCHHHHHHHHCCEEECCCCCCEEEEEEECCEEECCCCCCHHH
EPAIQYLADQNIVLSLDMYTAAKRDFIEVFVESILKPRGLSYKIQFPGPTGTNANEAALA
HHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
LARKYTGRSSVMAFTNSYHGMSLGSLAVSGSASTRQLGGVARHDVIRVPYENYPNQTFDS
HHHHHCCCCCEEEEECCCCCCEECCEEECCCCCHHHHCCHHHCCEEECCCCCCCCCCCCH
ASYIDHVLGDPGSGIEKPAAIILEPIQAEGGMNTASAPWLSEIQRICRKHDVVFIVDDIQ
HHHHHHHHCCCCCCCCCCCEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCC
AGSGRTGDFFSFEFAKIEPDIVCLSKSLSGSGNPLSIVLIRPDMDIWNPGEHSGTFRGNN
CCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
LAFVTSAAMCKMWSDRQFTTAVERTAVKLQEHLDRLVAKYPKCIEQKRGRGLMAGLKCRS
EEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
QAVVGRVHDVAFENGLLIESSGPNRDVIKVLPPITISDDELDHGIAILDQALQEKTNGD
HHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA