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The map label for this gene is iucD [H]

Identifier: 13474934

GI number: 13474934

Start: 4789201

End: 4790691

Strand: Direct

Name: iucD [H]

Synonym: mlr5923

Alternate gene names: 13474934

Gene position: 4789201-4790691 (Clockwise)

Preceding gene: 13474928

Following gene: 13474935

Centisome position: 68.07

GC content: 59.42

Gene sequence:

>1491_bases
ATGAGTGCCGATCTCATCAGGGAGCCGGCATCCGCGGGCGTCACACCCGATACTACGAACGCGCGGACAAGCTGCCACAA
GTCCGGCGGTGTCGACGATGCCTGCGGGGAGGGCAAGCCCAACGGCCATGGCCGACATTCGCTGCGCACAGCGTCTGTTT
GGGAAAGGTCAGTAGGAGCAAGACAACTGGATCTCTCTTGCATTGGGATCGGTGCTGGCCCGTCCAATTTGAGCCTTGCG
TGTCAGATACACGAGCAAATCGGGCACGGGGCACTATTCTTGGATCGGCAAGTCGACTTCCGCTGGCATCCAGGCAGCGC
ATTCGAGTCCTCAGAACTCCAGGTCAGCCACATCAAGGATCTGGTCACGCTGGTGAATCCGCAGTCAGCCTACACTTTCA
TAAACTACCTGCACGAGAACGGGCGTCTGTATCACTTCCTGAATGCACAGTTCGATGCTGTGCTCAGGGCTGAGTTCGAG
CAATACCTGAACTGGGCGTTCCGCAGAAACCCACTTGTGCGCGGCGGCGAGACCGTGCGCGAAATACGCTATGATGGCGA
GTTTCGGGTGCGGACGGACGACGCGGTGCTTAGTGCCAGAGACCTGGTGGTCGGCATCGGCAAGCAAGCATGGATTCCAC
CTCAATTTCAGGGCTGGATCGGACGCAACCTGTTCCATTCATCCGATTTGCTGCACATCCATCCTGAGGTGCGGCAAAAA
CATGTTTGCGTCGTTGGTGGAGGCCAGTCGGGAGCCGAGGTATTGTTGCATTTGGTCGGTGGGCCAAGAGAACGGCGGCC
TGCCTCGATCACCTGGGTCTCGCAGCGCGAAAACTACCTGCCCCTCGACAACAGCCCGTTCACAAACGAGTTGTTCATGC
CTTGTTTTTCGGATCGTTTCGCGGCAATGAGCGAGCCGCAGCGCAAGCTGTTCCTGCGGCGTTTCGTGCTCGCCTCGGAT
GGTATTTCGGATCGCACTTTGCGCGCCGTCTACCAGGCGCTATATCGCCACGAATTTCTTGAGCCAGACCTATGTGACAT
CGCACTTCGGCCGGGTTGCAACGTTTCGCGCTGCATCAACGCCGGCGCGGGTCACAACTTGACGCTGCAGCGCGGCTTGG
GCGACGTCGAAGAAGTCACGGCCGACATCGTCATCCTGGCCACCGGTTACGAGAACGCCGTGCCAAGCTTTTTGGAACCG
ATGGCGGATCGGCTGCAACAGACCGACAATGAGTTGGTCATCAACGCGGATTTTTCGGTGTGCTGGGACGGACCGCGTGA
CAGACGCATCTTCGTACAGAACGCCAATCCCGGGCAGCGCGGGCTGGCCGATCCGAACCTAAGCCTGCTGGCCTGGCGAG
CTCGCCGCATTCTTGACAGCCTTCTACAGCGCGCGCCGTGCGCGAACCCTGAGCATCCTGGCTTTATCAGCCGTACCACC
GTCGAGAGCTGGCCCGACCCGGTAGCCGAAGAAATGGGCAGCGGGATATGA

Upstream 100 bases:

>100_bases
CAATTGCAATGAGGGATAGGCAGCGAGAGCATGTCACTGACCACGCGGGGGTCATCGAGGCGGGATTCTCGATGCCAGCC
ACGCGCAACACATCACCGGC

Downstream 100 bases:

>100_bases
CTCAGCGACTACTGATCATCGGCGGTGGCATCCAAGGAATGATGTCCGCCTCCGCTGCGGCGCAGTCCGGAGCCCGCTCC
GAACTCATCGTGACTGAACA

Product: lysine:N6-hydroxylase

Products: NA

Alternate protein names: Lysine 6-N-hydroxylase; Lysine N(6)-hydroxylase; Lysine-N-oxygenase [H]

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSADLIREPASAGVTPDTTNARTSCHKSGGVDDACGEGKPNGHGRHSLRTASVWERSVGARQLDLSCIGIGAGPSNLSLA
CQIHEQIGHGALFLDRQVDFRWHPGSAFESSELQVSHIKDLVTLVNPQSAYTFINYLHENGRLYHFLNAQFDAVLRAEFE
QYLNWAFRRNPLVRGGETVREIRYDGEFRVRTDDAVLSARDLVVGIGKQAWIPPQFQGWIGRNLFHSSDLLHIHPEVRQK
HVCVVGGGQSGAEVLLHLVGGPRERRPASITWVSQRENYLPLDNSPFTNELFMPCFSDRFAAMSEPQRKLFLRRFVLASD
GISDRTLRAVYQALYRHEFLEPDLCDIALRPGCNVSRCINAGAGHNLTLQRGLGDVEEVTADIVILATGYENAVPSFLEP
MADRLQQTDNELVINADFSVCWDGPRDRRIFVQNANPGQRGLADPNLSLLAWRARRILDSLLQRAPCANPEHPGFISRTT
VESWPDPVAEEMGSGI

Sequences:

>Translated_496_residues
MSADLIREPASAGVTPDTTNARTSCHKSGGVDDACGEGKPNGHGRHSLRTASVWERSVGARQLDLSCIGIGAGPSNLSLA
CQIHEQIGHGALFLDRQVDFRWHPGSAFESSELQVSHIKDLVTLVNPQSAYTFINYLHENGRLYHFLNAQFDAVLRAEFE
QYLNWAFRRNPLVRGGETVREIRYDGEFRVRTDDAVLSARDLVVGIGKQAWIPPQFQGWIGRNLFHSSDLLHIHPEVRQK
HVCVVGGGQSGAEVLLHLVGGPRERRPASITWVSQRENYLPLDNSPFTNELFMPCFSDRFAAMSEPQRKLFLRRFVLASD
GISDRTLRAVYQALYRHEFLEPDLCDIALRPGCNVSRCINAGAGHNLTLQRGLGDVEEVTADIVILATGYENAVPSFLEP
MADRLQQTDNELVINADFSVCWDGPRDRRIFVQNANPGQRGLADPNLSLLAWRARRILDSLLQRAPCANPEHPGFISRTT
VESWPDPVAEEMGSGI
>Mature_495_residues
SADLIREPASAGVTPDTTNARTSCHKSGGVDDACGEGKPNGHGRHSLRTASVWERSVGARQLDLSCIGIGAGPSNLSLAC
QIHEQIGHGALFLDRQVDFRWHPGSAFESSELQVSHIKDLVTLVNPQSAYTFINYLHENGRLYHFLNAQFDAVLRAEFEQ
YLNWAFRRNPLVRGGETVREIRYDGEFRVRTDDAVLSARDLVVGIGKQAWIPPQFQGWIGRNLFHSSDLLHIHPEVRQKH
VCVVGGGQSGAEVLLHLVGGPRERRPASITWVSQRENYLPLDNSPFTNELFMPCFSDRFAAMSEPQRKLFLRRFVLASDG
ISDRTLRAVYQALYRHEFLEPDLCDIALRPGCNVSRCINAGAGHNLTLQRGLGDVEEVTADIVILATGYENAVPSFLEPM
ADRLQQTDNELVINADFSVCWDGPRDRRIFVQNANPGQRGLADPNLSLLAWRARRILDSLLQRAPCANPEHPGFISRTTV
ESWPDPVAEEMGSGI

Specific function: This is one of the proteins involved in the biosynthesis of siderophores (such as the dihydroxamate siderophore, aerobactin), which are chelators that mediate the high-affinity iron transport systems induced by the organism under iron-stressed conditions

COG id: COG3486

COG function: function code Q; Lysine/ornithine N-monooxygenase

Gene ontology:

Cell location: Cytoplasm. Cell membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.14.13.59 [H]

Molecular weight: Translated: 55189; Mature: 55058

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADLIREPASAGVTPDTTNARTSCHKSGGVDDACGEGKPNGHGRHSLRTASVWERSVGA
CCCHHHCCCHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
RQLDLSCIGIGAGPSNLSLACQIHEQIGHGALFLDRQVDFRWHPGSAFESSELQVSHIKD
EEEEEEEEEECCCCCCCEEEEEEHHHHCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHH
LVTLVNPQSAYTFINYLHENGRLYHFLNAQFDAVLRAEFEQYLNWAFRRNPLVRGGETVR
HHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
EIRYDGEFRVRTDDAVLSARDLVVGIGKQAWIPPQFQGWIGRNLFHSSDLLHIHPEVRQK
HHCCCCCEEEECCHHHHHHHHHEEECCCCCCCCCHHHHHHCCCHHCCCCEEEECHHHCCC
HVCVVGGGQSGAEVLLHLVGGPRERRPASITWVSQRENYLPLDNSPFTNELFMPCFSDRF
EEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHH
AAMSEPQRKLFLRRFVLASDGISDRTLRAVYQALYRHEFLEPDLCDIALRPGCNVSRCIN
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHC
AGAGHNLTLQRGLGDVEEVTADIVILATGYENAVPSFLEPMADRLQQTDNELVINADFSV
CCCCCCEEHHCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEE
CWDGPRDRRIFVQNANPGQRGLADPNLSLLAWRARRILDSLLQRAPCANPEHPGFISRTT
EECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECC
VESWPDPVAEEMGSGI
HHCCCCHHHHHHCCCC
>Mature Secondary Structure 
SADLIREPASAGVTPDTTNARTSCHKSGGVDDACGEGKPNGHGRHSLRTASVWERSVGA
CCHHHCCCHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
RQLDLSCIGIGAGPSNLSLACQIHEQIGHGALFLDRQVDFRWHPGSAFESSELQVSHIKD
EEEEEEEEEECCCCCCCEEEEEEHHHHCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHH
LVTLVNPQSAYTFINYLHENGRLYHFLNAQFDAVLRAEFEQYLNWAFRRNPLVRGGETVR
HHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
EIRYDGEFRVRTDDAVLSARDLVVGIGKQAWIPPQFQGWIGRNLFHSSDLLHIHPEVRQK
HHCCCCCEEEECCHHHHHHHHHEEECCCCCCCCCHHHHHHCCCHHCCCCEEEECHHHCCC
HVCVVGGGQSGAEVLLHLVGGPRERRPASITWVSQRENYLPLDNSPFTNELFMPCFSDRF
EEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHCCHHHHHH
AAMSEPQRKLFLRRFVLASDGISDRTLRAVYQALYRHEFLEPDLCDIALRPGCNVSRCIN
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHC
AGAGHNLTLQRGLGDVEEVTADIVILATGYENAVPSFLEPMADRLQQTDNELVINADFSV
CCCCCCEEHHCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECCCEE
CWDGPRDRRIFVQNANPGQRGLADPNLSLLAWRARRILDSLLQRAPCANPEHPGFISRTT
EECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECC
VESWPDPVAEEMGSGI
HHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3275632; 10064136 [H]