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The map label for this gene is gbpR [H]

Identifier: 13474712

GI number: 13474712

Start: 4551287

End: 4552177

Strand: Direct

Name: gbpR [H]

Synonym: mlr5660

Alternate gene names: 13474712

Gene position: 4551287-4552177 (Clockwise)

Preceding gene: 13474707

Following gene: 13474714

Centisome position: 64.69

GC content: 63.97

Gene sequence:

>891_bases
ATGCGCATGATCGTCGCGCTCGACGATCACGGTCGGGTGAGCGCGGCGGCGCAGGTCATGAACATTTCGCAGCCGGCGGC
ATCGCGCATGATTGCCGAGATGGAGGCGGTGCTCGAGGTCAAGCTGTGCGACAGGCTGCCGCGCGGCATCACGCTGACGC
CCTATGGCAAGGCGCTGGCAAGGCGTGGGCGTTCGATCCTGCTGGAAATGCGCGAGGTCGATCGCGAGATTTCCGAGCTC
AAGGCGGGCAAGGGCGGTTCCGTATTTCTTGGTGCCGTGACGGCGCCGGCGATCGAGCTGGCGGTGCCGGCGATCCGCGA
AATCCGCCGCATCTATCCACGCATCGAGATCACCATGCAGGTCGAGACCTCGAATGTGCTGGCGCGCGAACTGATCGCCT
CGCGCCACGATTTCATCATCGCGCGCATCCCCGACGATCTCAATCCGCGGCTGTTCGAATCGCGTGTCATCGGCGTCGAG
AAAGCCTGCCTGATCGTGCGTCGTGGCCACCCGCTGACCAGCGGCAGCGTGGTGCGGCTCGAAGACACTGCCGCCTATGA
CTGGGTTTTCCAGTCGGGCGGCTCGCCTTTGCGTCAGGCGATGGAGAGCAATTTCCTCAACCGCAACATCGCGCTGCCGG
ACCGGATCCTCAACACCAGTTCGCTGCTCCTGACGCTGGTCATGGTCGCGCAGTCCGACGCCATCGCGCCGGTCTCGGTG
CAGGTGGCGAAATTCATCCAGAATCCCGACGGACTCGCCGGCGCTATCGATGTCGTCCAGACCGAGTTCGACATCGAGGT
AAGGCCTTACAGCCTGATCACGGTCAGGAACCGCGCGCTGTCGCCGGCCGCCAAGATGCTGCACGATTTCATCCTGCGCG
AAGTGGGGTGA

Upstream 100 bases:

>100_bases
CATGGCGGCGTTACGGAATCCGGCTGCGGGTTCAAATGATTACAACGAGACCCCAGGCGATGGCGGAACCCTGCTGCGCA
GCGGCCTCAGCCTGCGTCAT

Downstream 100 bases:

>100_bases
TGGAACAAGAAGTGCAGTCGCGCGTTCAGGCCAATCGGCATGCTCGCTGGAGTTGTCTTGGGCGAGCGAACGAGGTGCCG
ATGTCAACAACTCGGGAGGT

Product: transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRMIVALDDHGRVSAAAQVMNISQPAASRMIAEMEAVLEVKLCDRLPRGITLTPYGKALARRGRSILLEMREVDREISEL
KAGKGGSVFLGAVTAPAIELAVPAIREIRRIYPRIEITMQVETSNVLARELIASRHDFIIARIPDDLNPRLFESRVIGVE
KACLIVRRGHPLTSGSVVRLEDTAAYDWVFQSGGSPLRQAMESNFLNRNIALPDRILNTSSLLLTLVMVAQSDAIAPVSV
QVAKFIQNPDGLAGAIDVVQTEFDIEVRPYSLITVRNRALSPAAKMLHDFILREVG

Sequences:

>Translated_296_residues
MRMIVALDDHGRVSAAAQVMNISQPAASRMIAEMEAVLEVKLCDRLPRGITLTPYGKALARRGRSILLEMREVDREISEL
KAGKGGSVFLGAVTAPAIELAVPAIREIRRIYPRIEITMQVETSNVLARELIASRHDFIIARIPDDLNPRLFESRVIGVE
KACLIVRRGHPLTSGSVVRLEDTAAYDWVFQSGGSPLRQAMESNFLNRNIALPDRILNTSSLLLTLVMVAQSDAIAPVSV
QVAKFIQNPDGLAGAIDVVQTEFDIEVRPYSLITVRNRALSPAAKMLHDFILREVG
>Mature_296_residues
MRMIVALDDHGRVSAAAQVMNISQPAASRMIAEMEAVLEVKLCDRLPRGITLTPYGKALARRGRSILLEMREVDREISEL
KAGKGGSVFLGAVTAPAIELAVPAIREIRRIYPRIEITMQVETSNVLARELIASRHDFIIARIPDDLNPRLFESRVIGVE
KACLIVRRGHPLTSGSVVRLEDTAAYDWVFQSGGSPLRQAMESNFLNRNIALPDRILNTSSLLLTLVMVAQSDAIAPVSV
QVAKFIQNPDGLAGAIDVVQTEFDIEVRPYSLITVRNRALSPAAKMLHDFILREVG

Specific function: Activator of the expression of chvE when bound to its inducer and represses its expression in the absence of inducer (L- arabinose, D-fucose or D-galactose). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=191, Percent_Identity=28.2722513089005, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=238, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788297, Length=141, Percent_Identity=29.0780141843972, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1789506, Length=284, Percent_Identity=22.5352112676056, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32584; Mature: 32584

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMIVALDDHGRVSAAAQVMNISQPAASRMIAEMEAVLEVKLCDRLPRGITLTPYGKALA
CEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHH
RRGRSILLEMREVDREISELKAGKGGSVFLGAVTAPAIELAVPAIREIRRIYPRIEITMQ
HCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHCCCEEEEEE
VETSNVLARELIASRHDFIIARIPDDLNPRLFESRVIGVEKACLIVRRGHPLTSGSVVRL
EECHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHHEEEEEECCCCCCCCCEEEE
EDTAAYDWVFQSGGSPLRQAMESNFLNRNIALPDRILNTSSLLLTLVMVAQSDAIAPVSV
ECCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
QVAKFIQNPDGLAGAIDVVQTEFDIEVRPYSLITVRNRALSPAAKMLHDFILREVG
HHHHHHCCCCCCHHHHHHEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRMIVALDDHGRVSAAAQVMNISQPAASRMIAEMEAVLEVKLCDRLPRGITLTPYGKALA
CEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHH
RRGRSILLEMREVDREISELKAGKGGSVFLGAVTAPAIELAVPAIREIRRIYPRIEITMQ
HCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCHHHHHHHHHHHHHHHCCCEEEEEE
VETSNVLARELIASRHDFIIARIPDDLNPRLFESRVIGVEKACLIVRRGHPLTSGSVVRL
EECHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCHHHEEEEEECCCCCCCCCEEEE
EDTAAYDWVFQSGGSPLRQAMESNFLNRNIALPDRILNTSSLLLTLVMVAQSDAIAPVSV
ECCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
QVAKFIQNPDGLAGAIDVVQTEFDIEVRPYSLITVRNRALSPAAKMLHDFILREVG
HHHHHHCCCCCCHHHHHHEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8253677; 2156804 [H]