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The map label for this gene is csd [H]

Identifier: 13474521

GI number: 13474521

Start: 4338399

End: 4339673

Strand: Reverse

Name: csd [H]

Synonym: mll5421

Alternate gene names: 13474521

Gene position: 4339673-4338399 (Counterclockwise)

Preceding gene: 13474522

Following gene: 13474515

Centisome position: 61.68

GC content: 63.22

Gene sequence:

>1275_bases
GTGAACAAGCACCAAACCGACAATGCGAACGCCGCCGCGTTCCCCGTCGACACCATCCGCACCATGTTTCCCGCCTTGCA
ACGGGCCGGCGATTTCATCTTCATGGATAATGCCGCCGGCGCGCAGATCCCGCAGAGCGTGCTTGACGCGGTGACCAACC
ATCTGGTTTCGCACAATGTGCAGCGCGGCGGCCGCTATGGCCGCAGCGTCACCGTCGATCAGTCGGTCGCTGATGCCCGG
ACGAGCGTGGCGCTGCTGATCAATGCCTATAGCCCGGCGGAAATCTGCTTCGGCATGAACGCCACCTCGTTCATCCGCCT
GGTCAGCCTCGGGATCGGCCAGATGCTCTCGGAACGCGACGAGATCGTCATCACCGACATGGACCACGACGCCAACATCG
CCACCTGGCTGGCGCTGGAAACCGCCGGCGCCAAGTTCAAGTGGTGGCGCATGCGCGAGGACGGCAATCTGCATGTCGAC
GATCTGCGCCCGCTGGTTTCCGACCGTACCCGCCTCGTCGCCTGCACGGTGACGGCGCATTCGATCGGCTCGATCGTCGA
TGTCGCATCGGTGGCCGAGATCGCGCATGCGGCCGGCGCGGAAGTGTTCCTCGACTGCGTGCATTACGGGCCGCACGGGC
TGATCGACGTGCAGGCCTGGGATTGCGATTATCTCGTCTGCTCCGGCTACAAGAATTTCTCGCCGCATATGGGTTTTCTC
TGGGGCCGCTTCGACACGCTGAAGCGGCTGCCGACTTTTCGGGAGGATTTCATCCCCGACGAGCCGCCCTACAAGGTCGA
GGCCGGCACCTTCATCTACGAGAATGTCTCGGGCATGGACGCGGCCGTGCAGTATCTGGAACTGATCGGCCGCAATCTGG
CCCCCTCCAACAACCGCTCGCGGCGCGAGAACATCGTCGCCGGCATGGGCGCCATCCGCGACTATGAGCTGCTTCTGGCG
CGCGAGATGCTTGCCGTGCTGAAAGGTTGCGGCGCGACCATCTACGGCGTCGCCGACGAGGCCCGTCTCAACGAGCGCGT
GCCGACCTTCTGCTTCAACATCGGCAGACTGTCACCGCAACGGATCGTCGAGGAAATGGCCGACATGCAGATCGGCATCC
GCGACGGCCATATGTACGCGCCGCGGCTGATGAAGCGCCTCAATTTGTCGATGGACAGCGGCGCCATCCGCGCCTCGCTG
GTGCACTACAACACGGTCGAGGAAGTGCACAAATTTGGCGAAGCATTGCGCGCGATTATCGCCAGGCTGTCGTGA

Upstream 100 bases:

>100_bases
TCGCCTCGTCAGCCTGCTTGAAGACCGCTTCAAGACCGAGAAAGCGCGCTAACCTCGCCAACCGATCTCCACCCGCCCAA
TTCTTCGCAGGAGCCTGCCC

Downstream 100 bases:

>100_bases
TCGATGAGGGGGTGGCCTGACAGCTGCGACCAGCAGCCTCAGGCCGCCGCCTTCTTCTTCGCCAGCCTCGCCTTGATCGA
GGCGACGTCGGCGCGCGGCG

Product: aminotransferase nifS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MNKHQTDNANAAAFPVDTIRTMFPALQRAGDFIFMDNAAGAQIPQSVLDAVTNHLVSHNVQRGGRYGRSVTVDQSVADAR
TSVALLINAYSPAEICFGMNATSFIRLVSLGIGQMLSERDEIVITDMDHDANIATWLALETAGAKFKWWRMREDGNLHVD
DLRPLVSDRTRLVACTVTAHSIGSIVDVASVAEIAHAAGAEVFLDCVHYGPHGLIDVQAWDCDYLVCSGYKNFSPHMGFL
WGRFDTLKRLPTFREDFIPDEPPYKVEAGTFIYENVSGMDAAVQYLELIGRNLAPSNNRSRRENIVAGMGAIRDYELLLA
REMLAVLKGCGATIYGVADEARLNERVPTFCFNIGRLSPQRIVEEMADMQIGIRDGHMYAPRLMKRLNLSMDSGAIRASL
VHYNTVEEVHKFGEALRAIIARLS

Sequences:

>Translated_424_residues
MNKHQTDNANAAAFPVDTIRTMFPALQRAGDFIFMDNAAGAQIPQSVLDAVTNHLVSHNVQRGGRYGRSVTVDQSVADAR
TSVALLINAYSPAEICFGMNATSFIRLVSLGIGQMLSERDEIVITDMDHDANIATWLALETAGAKFKWWRMREDGNLHVD
DLRPLVSDRTRLVACTVTAHSIGSIVDVASVAEIAHAAGAEVFLDCVHYGPHGLIDVQAWDCDYLVCSGYKNFSPHMGFL
WGRFDTLKRLPTFREDFIPDEPPYKVEAGTFIYENVSGMDAAVQYLELIGRNLAPSNNRSRRENIVAGMGAIRDYELLLA
REMLAVLKGCGATIYGVADEARLNERVPTFCFNIGRLSPQRIVEEMADMQIGIRDGHMYAPRLMKRLNLSMDSGAIRASL
VHYNTVEEVHKFGEALRAIIARLS
>Mature_424_residues
MNKHQTDNANAAAFPVDTIRTMFPALQRAGDFIFMDNAAGAQIPQSVLDAVTNHLVSHNVQRGGRYGRSVTVDQSVADAR
TSVALLINAYSPAEICFGMNATSFIRLVSLGIGQMLSERDEIVITDMDHDANIATWLALETAGAKFKWWRMREDGNLHVD
DLRPLVSDRTRLVACTVTAHSIGSIVDVASVAEIAHAAGAEVFLDCVHYGPHGLIDVQAWDCDYLVCSGYKNFSPHMGFL
WGRFDTLKRLPTFREDFIPDEPPYKVEAGTFIYENVSGMDAAVQYLELIGRNLAPSNNRSRRENIVAGMGAIRDYELLLA
REMLAVLKGCGATIYGVADEARLNERVPTFCFNIGRLSPQRIVEEMADMQIGIRDGHMYAPRLMKRLNLSMDSGAIRASL
VHYNTVEEVHKFGEALRAIIARLS

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=428, Percent_Identity=29.6728971962617, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789175, Length=407, Percent_Identity=28.009828009828, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46939; Mature: 46939

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKHQTDNANAAAFPVDTIRTMFPALQRAGDFIFMDNAAGAQIPQSVLDAVTNHLVSHNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
QRGGRYGRSVTVDQSVADARTSVALLINAYSPAEICFGMNATSFIRLVSLGIGQMLSERD
HHCCCCCCEEEECHHHHHHHHEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCC
EIVITDMDHDANIATWLALETAGAKFKWWRMREDGNLHVDDLRPLVSDRTRLVACTVTAH
CEEEEECCCCCCEEEEEEEECCCCCEEEEEECCCCCEEHHHHHHHHCCCCEEEEEEEEHH
SIGSIVDVASVAEIAHAAGAEVFLDCVHYGPHGLIDVQAWDCDYLVCSGYKNFSPHMGFL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCHH
WGRFDTLKRLPTFREDFIPDEPPYKVEAGTFIYENVSGMDAAVQYLELIGRNLAPSNNRS
HHHHHHHHHCCCHHHHCCCCCCCCEEECCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
RRENIVAGMGAIRDYELLLAREMLAVLKGCGATIYGVADEARLNERVPTFCFNIGRLSPQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCHHHHHCCCCCHH
RIVEEMADMQIGIRDGHMYAPRLMKRLNLSMDSGAIRASLVHYNTVEEVHKFGEALRAII
HHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
ARLS
HHCC
>Mature Secondary Structure
MNKHQTDNANAAAFPVDTIRTMFPALQRAGDFIFMDNAAGAQIPQSVLDAVTNHLVSHNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
QRGGRYGRSVTVDQSVADARTSVALLINAYSPAEICFGMNATSFIRLVSLGIGQMLSERD
HHCCCCCCEEEECHHHHHHHHEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCC
EIVITDMDHDANIATWLALETAGAKFKWWRMREDGNLHVDDLRPLVSDRTRLVACTVTAH
CEEEEECCCCCCEEEEEEEECCCCCEEEEEECCCCCEEHHHHHHHHCCCCEEEEEEEEHH
SIGSIVDVASVAEIAHAAGAEVFLDCVHYGPHGLIDVQAWDCDYLVCSGYKNFSPHMGFL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCHH
WGRFDTLKRLPTFREDFIPDEPPYKVEAGTFIYENVSGMDAAVQYLELIGRNLAPSNNRS
HHHHHHHHHCCCHHHHCCCCCCCCEEECCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
RRENIVAGMGAIRDYELLLAREMLAVLKGCGATIYGVADEARLNERVPTFCFNIGRLSPQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCHHHHHCCCCCHH
RIVEEMADMQIGIRDGHMYAPRLMKRLNLSMDSGAIRASLVHYNTVEEVHKFGEALRAII
HHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
ARLS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]