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The map label for this gene is yieH [H]

Identifier: 13474456

GI number: 13474456

Start: 4268394

End: 4269053

Strand: Reverse

Name: yieH [H]

Synonym: mll5344

Alternate gene names: 13474456

Gene position: 4269053-4268394 (Counterclockwise)

Preceding gene: 13474457

Following gene: 13474455

Centisome position: 60.67

GC content: 62.27

Gene sequence:

>660_bases
ATGCAAATACCCAAGCTTGTGATCTTCGACTGCGACGGGATTCTCGTCGACACGGAGAATCTCGCCAATCGACGCCTCGC
TGAATGGTTGACGGCTGCCGGCTATCCGACAAGCTTCGAATATTGCCGCAAGAATTTCTCCGGCCGCAGCATGGCCTCGG
TCCAGAAAGAGATCGAGGAGACGACCGAGGTCCGGCTCGGCGCCGATTTCGTCGAGCGTTGGAATGCCGGCCTGCCGGAC
CTGTTTTCCCATGGCGTCGAGGCAATCCCTTACGTCCGCGAGTTCGTCGAAGCGGTGCGCGCGGCCGGCATTGCCTATTG
CGTCGCCACGTCGGCCAGGATTTCGAAGATGCACATCACGCTTGGCCAGACCGGACTGTTGCCGCTGTTCGAACATGCGA
TGTTTTCGTCGACCATGGTCGGGCGCGGCAAGCCGTTCCCTGACCTGTTCCTGCATGCGGCCAAGACCATGGGCTTCGCG
CCGGCCGATTGCATCGTCATCGAGGACAGCGTCGCCGGCACGCAGGCCGGGATCACCGCCGGCATGCGGGTGTTCTCCTA
TCATGGCGATCCCCATTCCGACCGCGATGGCCTGATCGAGGCCGGCGGCATCCTGTTCGACGACATGCGCGAACTGGCCG
GACTGGTGCCGATCCACTGA

Upstream 100 bases:

>100_bases
TCGTTTTCGCTGTTGTGACGCAGGCGGCCGTCGAGGAGCGTTCGCTGGCCGGCGGCACGGCACGCGGTTCGGGCGGGTTC
GGATCGACCGGCACCGTCTG

Downstream 100 bases:

>100_bases
TCCGGTTCCAGCACGGCTGCGCGATGCTGGAACCCGTGCTAGCGTGAGTGGCCTGATCTTGGGGGGCGCCCATGCCAACG
AACCTTTTCCGCTTCATCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MQIPKLVIFDCDGILVDTENLANRRLAEWLTAAGYPTSFEYCRKNFSGRSMASVQKEIEETTEVRLGADFVERWNAGLPD
LFSHGVEAIPYVREFVEAVRAAGIAYCVATSARISKMHITLGQTGLLPLFEHAMFSSTMVGRGKPFPDLFLHAAKTMGFA
PADCIVIEDSVAGTQAGITAGMRVFSYHGDPHSDRDGLIEAGGILFDDMRELAGLVPIH

Sequences:

>Translated_219_residues
MQIPKLVIFDCDGILVDTENLANRRLAEWLTAAGYPTSFEYCRKNFSGRSMASVQKEIEETTEVRLGADFVERWNAGLPD
LFSHGVEAIPYVREFVEAVRAAGIAYCVATSARISKMHITLGQTGLLPLFEHAMFSSTMVGRGKPFPDLFLHAAKTMGFA
PADCIVIEDSVAGTQAGITAGMRVFSYHGDPHSDRDGLIEAGGILFDDMRELAGLVPIH
>Mature_219_residues
MQIPKLVIFDCDGILVDTENLANRRLAEWLTAAGYPTSFEYCRKNFSGRSMASVQKEIEETTEVRLGADFVERWNAGLPD
LFSHGVEAIPYVREFVEAVRAAGIAYCVATSARISKMHITLGQTGLLPLFEHAMFSSTMVGRGKPFPDLFLHAAKTMGFA
PADCIVIEDSVAGTQAGITAGMRVFSYHGDPHSDRDGLIEAGGILFDDMRELAGLVPIH

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=188, Percent_Identity=34.0425531914894, Blast_Score=102, Evalue=2e-23,
Organism=Drosophila melanogaster, GI116008157, Length=203, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17137324, Length=203, Percent_Identity=28.0788177339901, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129151, Length=187, Percent_Identity=28.8770053475936, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 23928; Mature: 23928

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIPKLVIFDCDGILVDTENLANRRLAEWLTAAGYPTSFEYCRKNFSGRSMASVQKEIEE
CCCCCEEEEECCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHH
TTEVRLGADFVERWNAGLPDLFSHGVEAIPYVREFVEAVRAAGIAYCVATSARISKMHIT
HHHHHHCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
LGQTGLLPLFEHAMFSSTMVGRGKPFPDLFLHAAKTMGFAPADCIVIEDSVAGTQAGITA
ECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHH
GMRVFSYHGDPHSDRDGLIEAGGILFDDMRELAGLVPIH
HHHEEEECCCCCCCCCCEECCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQIPKLVIFDCDGILVDTENLANRRLAEWLTAAGYPTSFEYCRKNFSGRSMASVQKEIEE
CCCCCEEEEECCCEEEECHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHH
TTEVRLGADFVERWNAGLPDLFSHGVEAIPYVREFVEAVRAAGIAYCVATSARISKMHIT
HHHHHHCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
LGQTGLLPLFEHAMFSSTMVGRGKPFPDLFLHAAKTMGFAPADCIVIEDSVAGTQAGITA
ECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHH
GMRVFSYHGDPHSDRDGLIEAGGILFDDMRELAGLVPIH
HHHEEEECCCCCCCCCCEECCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]