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The map label for this gene is soxB [H]

Identifier: 13474362

GI number: 13474362

Start: 4162983

End: 4164236

Strand: Reverse

Name: soxB [H]

Synonym: mll5232

Alternate gene names: 13474362

Gene position: 4164236-4162983 (Counterclockwise)

Preceding gene: 13474363

Following gene: 13474361

Centisome position: 59.18

GC content: 65.79

Gene sequence:

>1254_bases
ATGACCCGTCGTTATTCCGCTTTGTCGCTCATCAAGGAGGGCCTGGCCGGCCAGACCGGCTGGAAGCAGGCCTGGCGCTC
GCCCGAGCCGAAGCCGACCTACGACGCGATCATCATCGGCGGCGGCGGCCACGGGCTGGCGACAGCCTACTACCTGGCCA
ACAATCACGGCATCACCCGGGTCGCAGTGCTGGAAAAGGGCTGGATCGGCGGCGGCAATACCGGCCGCAACACCACCGTG
GTGCGCTCCAACTACTATTATCCCGAAAGCGTCGAACTCTACGGGCTGGCGCACCGGCTCTATGAAGGCCTGTCGAAGGA
CCTGAATTACAACGTCATGCTGTCGCAGCGCGGCATGGTCAATCTGTGCCATTCGACGGCCGAAATGGAGATCGGCGCGC
GCACCGTCAACGCCATGCAGATCAACGGCATCGATGCGGAGTTGTTTTCGCCAGAGGATGTGCGCCGCGTGGCGCCGATC
TACAATTTCTCTCCGGATGCGCGCTTTCCGGTGTTCGGCGGCATCTGGCAAGGCAGGGCTGGAACCGCGCGCCATGACGC
GGTCGCCTGGGGCTATGCGCGGGCGGCGAGCCGGCTCGGCGTCGACATCATCCAGAACTGCGAGATCACCGATTTCATCG
TCGAAGGCGGCCGCTGCCGCGGCGTCCAGACGACGCGCGGCGCGATCCGCGCCGAGCGCATCGGCATGGCCGTGGCCGGC
CATTCCTCGGTGCTGGCGGCCAAGGCCGGTTTCAGGCTGCCGATCAATTCCTATGCACTACAGGCCTGCGTCTCCGAGCC
GGTGAAGCCGATCCTCGACACGGTGGTGCTGTCGCCAGGCTGCGGCGTCTATGTCAGCCAGTCGGACAAGGGCGAGATCG
TCATCGGCGGCGGGCTCGACCGCGTCCCCTCCTATGCGCAGCGCGGCAATCTGCCGACGCTGGAAACCGTGATCGCCGGG
CTGCTGGAAATGTTCCCGATCTTCGGCCAGCTGAAGCTGATGCGGCAATGGGCAGGGATCGTCGATGTCGTGCCGGACTC
CTCGCCGATCATCGGTCCCTCGCCGCTGCCCAACCTCTTCCTCAATTGCGGCTGGGGCACGGGCGGCTTCAAGGCCATTC
CTGCCGGCGGCACGCTGCTGGCGAACCTGCTGGCGACCGGCAAGCACAACGATATCAGCCGCCCCTTCGATCTCGATCGC
TTCGCCAGCGGGCGGCTGATCGACGAAGCGGCCGGCTCCGGCATCGCGCACTGA

Upstream 100 bases:

>100_bases
GCTAGCACCTTCCGCCGCGTGCAAGATCGATCCGCGAACTAGACATATATGTACAATACCATTACGCTTGCCCTGAGAAA
TCAGCCTTGTCCCGCACACC

Downstream 100 bases:

>100_bases
GACAAGAATCCGAGGCAATCATGCAGCTTTTCCCTTGCCCGTTCTGCGGTCCGCGCGACGAGACCGAATTCCACTATGGC
GGCGATGCCGGCAACGCCAG

Product: sarcosine oxidase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTRRYSALSLIKEGLAGQTGWKQAWRSPEPKPTYDAIIIGGGGHGLATAYYLANNHGITRVAVLEKGWIGGGNTGRNTTV
VRSNYYYPESVELYGLAHRLYEGLSKDLNYNVMLSQRGMVNLCHSTAEMEIGARTVNAMQINGIDAELFSPEDVRRVAPI
YNFSPDARFPVFGGIWQGRAGTARHDAVAWGYARAASRLGVDIIQNCEITDFIVEGGRCRGVQTTRGAIRAERIGMAVAG
HSSVLAAKAGFRLPINSYALQACVSEPVKPILDTVVLSPGCGVYVSQSDKGEIVIGGGLDRVPSYAQRGNLPTLETVIAG
LLEMFPIFGQLKLMRQWAGIVDVVPDSSPIIGPSPLPNLFLNCGWGTGGFKAIPAGGTLLANLLATGKHNDISRPFDLDR
FASGRLIDEAAGSGIAH

Sequences:

>Translated_417_residues
MTRRYSALSLIKEGLAGQTGWKQAWRSPEPKPTYDAIIIGGGGHGLATAYYLANNHGITRVAVLEKGWIGGGNTGRNTTV
VRSNYYYPESVELYGLAHRLYEGLSKDLNYNVMLSQRGMVNLCHSTAEMEIGARTVNAMQINGIDAELFSPEDVRRVAPI
YNFSPDARFPVFGGIWQGRAGTARHDAVAWGYARAASRLGVDIIQNCEITDFIVEGGRCRGVQTTRGAIRAERIGMAVAG
HSSVLAAKAGFRLPINSYALQACVSEPVKPILDTVVLSPGCGVYVSQSDKGEIVIGGGLDRVPSYAQRGNLPTLETVIAG
LLEMFPIFGQLKLMRQWAGIVDVVPDSSPIIGPSPLPNLFLNCGWGTGGFKAIPAGGTLLANLLATGKHNDISRPFDLDR
FASGRLIDEAAGSGIAH
>Mature_416_residues
TRRYSALSLIKEGLAGQTGWKQAWRSPEPKPTYDAIIIGGGGHGLATAYYLANNHGITRVAVLEKGWIGGGNTGRNTTVV
RSNYYYPESVELYGLAHRLYEGLSKDLNYNVMLSQRGMVNLCHSTAEMEIGARTVNAMQINGIDAELFSPEDVRRVAPIY
NFSPDARFPVFGGIWQGRAGTARHDAVAWGYARAASRLGVDIIQNCEITDFIVEGGRCRGVQTTRGAIRAERIGMAVAGH
SSVLAAKAGFRLPINSYALQACVSEPVKPILDTVVLSPGCGVYVSQSDKGEIVIGGGLDRVPSYAQRGNLPTLETVIAGL
LEMFPIFGQLKLMRQWAGIVDVVPDSSPIIGPSPLPNLFLNCGWGTGGFKAIPAGGTLLANLLATGKHNDISRPFDLDRF
ASGRLIDEAAGSGIAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=414, Percent_Identity=22.9468599033816, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI21361378, Length=414, Percent_Identity=22.9468599033816, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI194306651, Length=394, Percent_Identity=22.3350253807107, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1787438, Length=302, Percent_Identity=22.1854304635762, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130091, Length=386, Percent_Identity=24.6113989637306, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 44645; Mature: 44513

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRYSALSLIKEGLAGQTGWKQAWRSPEPKPTYDAIIIGGGGHGLATAYYLANNHGITR
CCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCEEE
VAVLEKGWIGGGNTGRNTTVVRSNYYYPESVELYGLAHRLYEGLSKDLNYNVMLSQRGMV
EEEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHH
NLCHSTAEMEIGARTVNAMQINGIDAELFSPEDVRRVAPIYNFSPDARFPVFGGIWQGRA
HHHHHHHHHEECCEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GTARHDAVAWGYARAASRLGVDIIQNCEITDFIVEGGRCRGVQTTRGAIRAERIGMAVAG
CCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCEECCCCHHHHHHHHHHHCEEEEC
HSSVLAAKAGFRLPINSYALQACVSEPVKPILDTVVLSPGCGVYVSQSDKGEIVIGGGLD
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCEEECCCHH
RVPSYAQRGNLPTLETVIAGLLEMFPIFGQLKLMRQWAGIVDVVPDSSPIIGPSPLPNLF
HCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCE
LNCGWGTGGFKAIPAGGTLLANLLATGKHNDISRPFDLDRFASGRLIDEAAGSGIAH
EECCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEHHHCCCCCCC
>Mature Secondary Structure 
TRRYSALSLIKEGLAGQTGWKQAWRSPEPKPTYDAIIIGGGGHGLATAYYLANNHGITR
CCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEEECCCCEEE
VAVLEKGWIGGGNTGRNTTVVRSNYYYPESVELYGLAHRLYEGLSKDLNYNVMLSQRGMV
EEEEECCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHH
NLCHSTAEMEIGARTVNAMQINGIDAELFSPEDVRRVAPIYNFSPDARFPVFGGIWQGRA
HHHHHHHHHEECCEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GTARHDAVAWGYARAASRLGVDIIQNCEITDFIVEGGRCRGVQTTRGAIRAERIGMAVAG
CCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEECCCEECCCCHHHHHHHHHHHCEEEEC
HSSVLAAKAGFRLPINSYALQACVSEPVKPILDTVVLSPGCGVYVSQSDKGEIVIGGGLD
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCEEECCCHH
RVPSYAQRGNLPTLETVIAGLLEMFPIFGQLKLMRQWAGIVDVVPDSSPIIGPSPLPNLF
HCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCE
LNCGWGTGGFKAIPAGGTLLANLLATGKHNDISRPFDLDRFASGRLIDEAAGSGIAH
EECCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]