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The map label for this gene is yciC [H]

Identifier: 13474299

GI number: 13474299

Start: 4091133

End: 4092440

Strand: Reverse

Name: yciC [H]

Synonym: mll5156

Alternate gene names: 13474299

Gene position: 4092440-4091133 (Counterclockwise)

Preceding gene: 13474301

Following gene: 13474298

Centisome position: 58.16

GC content: 61.09

Gene sequence:

>1308_bases
ATGACAAACGACTTTTGGCCGCACAGGAATCGCCGCCAAGGCGAGGCACGCGTGACATCAGAGGCACCTTGCTCGCCACA
AGGCGCGCTCCCGCAGTCATCCGGCATGCCGATAGCACAAGTGGCGGGCCAAGAGCTTTGGCCCATCGGTTTGCCCCGTG
CAAAAGCCCCGCACACATCCTATATGGAGCCGACAATCCCTTTTTCGCGGCCTGGATTTCAAGGCCCAGTCATCTCGAGG
CAAGCCATGAGCGACGCACAGACGCAGATCCCCGTAACCGTTCTCACCGGCTATCTCGGCGCCGGCAAGACGACGCTGCT
CAACCGCATCCTGTCGGAGAACCACGGCAGGCGCTACGCGGTCATCGTCAACGAATTCGGTGAAATCGGCATCGACAACG
ACCTGATCGTGGAATCCGACGAGGAAATCTACGAGATGAACAATGGCTGCGTCTGCTGCACTGTGCGCGGCGACCTGATC
CGTGTCGTCGAGGGCCTGATGCGCAGGCCCGGCCGCTTCGACGCCATCGTGGTCGAGACCACCGGCCTCGCCGATCCGGT
GCCGGTGGCGCAGACCTTCTTCATGGACGACGACGTGCGCTCCAAAACCAAGCTCGATGCGGTGGTGGCGCTGGTCGATG
CCAAGCATTTGCCGCTCAGGCTCAAGGATTCCAAGGAAGCCGAGGACCAGATTGCTTTCGCCGATGTCGTCGTGCTCAAC
AAGACCGATCTCGTCACCCCCGAAGAGCTCGCCAAGGTCGAGGCGACCATCCGCGCCATCAACCCGGCGGCGAAGATCCA
TCGCACCACCCGCGCCGGCGTCGCCCTGTCGGAAGTGCTCGACCGCGGCGCCTTCGACCTCTCCCGTGCACTGGAAAATG
ACCCGCATTTCCTCGAAGGTCATGACGATCACGACCATCATGACCACGACCACCACGATCACGATGGCCACCATCACCAT
GATCATGACGGGCACGACCATCACCATCACGACCATCCCTCCGACATCCATGACGTGACGGTGCAGTCGGTGTCGTTGCG
CGGCGGCGAGATGGACCCGAAGAAATTCTTCCCATGGATCGAGAAGATCACCCAGATGGAAGGCCCCAACATCCTGCGGC
TGAAGGGCATCATTGCACTCAAGGGCGATGATGAACGCTACGTCATCCAGGGCGTGCACATGATCATAGAGGGCGACCAT
CAGCGCGCCTGGAAAGACGGCGAGAAACATGAAAGCCGGCTCGTGTTCATCGGCCGCGAACTCGACGCCGAGCGGCTGAA
GAAGAGTTTTGACGCCTGCCAGGCCTAG

Upstream 100 bases:

>100_bases
GTTGGCAATCGACGATAAAAAGAATCCGGCGCGTGAAACAGCTTTGCCGGCAAGCATTGCGGTGCCCGCCGTGGTGATGC
CAGATGTTTATTTCAGTTAG

Downstream 100 bases:

>100_bases
TCAGGCTTTGCCGTGCGATTCCAGGCTGGATGTAATGATCGAAGAATTACTGCCGTGGAATTTCAGAAGCCGCCGTTGAC
GATCTTGCCGTTTCCACGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTNDFWPHRNRRQGEARVTSEAPCSPQGALPQSSGMPIAQVAGQELWPIGLPRAKAPHTSYMEPTIPFSRPGFQGPVISR
QAMSDAQTQIPVTVLTGYLGAGKTTLLNRILSENHGRRYAVIVNEFGEIGIDNDLIVESDEEIYEMNNGCVCCTVRGDLI
RVVEGLMRRPGRFDAIVVETTGLADPVPVAQTFFMDDDVRSKTKLDAVVALVDAKHLPLRLKDSKEAEDQIAFADVVVLN
KTDLVTPEELAKVEATIRAINPAAKIHRTTRAGVALSEVLDRGAFDLSRALENDPHFLEGHDDHDHHDHDHHDHDGHHHH
DHDGHDHHHHDHPSDIHDVTVQSVSLRGGEMDPKKFFPWIEKITQMEGPNILRLKGIIALKGDDERYVIQGVHMIIEGDH
QRAWKDGEKHESRLVFIGRELDAERLKKSFDACQA

Sequences:

>Translated_435_residues
MTNDFWPHRNRRQGEARVTSEAPCSPQGALPQSSGMPIAQVAGQELWPIGLPRAKAPHTSYMEPTIPFSRPGFQGPVISR
QAMSDAQTQIPVTVLTGYLGAGKTTLLNRILSENHGRRYAVIVNEFGEIGIDNDLIVESDEEIYEMNNGCVCCTVRGDLI
RVVEGLMRRPGRFDAIVVETTGLADPVPVAQTFFMDDDVRSKTKLDAVVALVDAKHLPLRLKDSKEAEDQIAFADVVVLN
KTDLVTPEELAKVEATIRAINPAAKIHRTTRAGVALSEVLDRGAFDLSRALENDPHFLEGHDDHDHHDHDHHDHDGHHHH
DHDGHDHHHHDHPSDIHDVTVQSVSLRGGEMDPKKFFPWIEKITQMEGPNILRLKGIIALKGDDERYVIQGVHMIIEGDH
QRAWKDGEKHESRLVFIGRELDAERLKKSFDACQA
>Mature_434_residues
TNDFWPHRNRRQGEARVTSEAPCSPQGALPQSSGMPIAQVAGQELWPIGLPRAKAPHTSYMEPTIPFSRPGFQGPVISRQ
AMSDAQTQIPVTVLTGYLGAGKTTLLNRILSENHGRRYAVIVNEFGEIGIDNDLIVESDEEIYEMNNGCVCCTVRGDLIR
VVEGLMRRPGRFDAIVVETTGLADPVPVAQTFFMDDDVRSKTKLDAVVALVDAKHLPLRLKDSKEAEDQIAFADVVVLNK
TDLVTPEELAKVEATIRAINPAAKIHRTTRAGVALSEVLDRGAFDLSRALENDPHFLEGHDDHDHHDHDHHDHDGHHHHD
HDGHDHHHHDHPSDIHDVTVQSVSLRGGEMDPKKFFPWIEKITQMEGPNILRLKGIIALKGDDERYVIQGVHMIIEGDHQ
RAWKDGEKHESRLVFIGRELDAERLKKSFDACQA

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=359, Percent_Identity=36.4902506963788, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI146231952, Length=359, Percent_Identity=36.4902506963788, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI33469141, Length=209, Percent_Identity=48.3253588516746, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI148727351, Length=209, Percent_Identity=47.3684210526316, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI223941779, Length=197, Percent_Identity=46.1928934010152, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI223941776, Length=198, Percent_Identity=46.4646464646465, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI119120938, Length=133, Percent_Identity=48.8721804511278, Blast_Score=138, Evalue=9e-33,
Organism=Escherichia coli, GI87082430, Length=346, Percent_Identity=32.0809248554913, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788499, Length=163, Percent_Identity=35.5828220858896, Blast_Score=93, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324356, Length=228, Percent_Identity=31.140350877193, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 48604; Mature: 48473

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00498 TYROSINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDFWPHRNRRQGEARVTSEAPCSPQGALPQSSGMPIAQVAGQELWPIGLPRAKAPHTS
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
YMEPTIPFSRPGFQGPVISRQAMSDAQTQIPVTVLTGYLGAGKTTLLNRILSENHGRRYA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEE
VIVNEFGEIGIDNDLIVESDEEIYEMNNGCVCCTVRGDLIRVVEGLMRRPGRFDAIVVET
EEEECCCCCCCCCCEEEECCHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEEEE
TGLADPVPVAQTFFMDDDVRSKTKLDAVVALVDAKHLPLRLKDSKEAEDQIAFADVVVLN
CCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHEEEEEEEEEC
KTDLVTPEELAKVEATIRAINPAAKIHRTTRAGVALSEVLDRGAFDLSRALENDPHFLEG
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECC
HDDHDHHDHDHHDHDGHHHHDHDGHDHHHHDHPSDIHDVTVQSVSLRGGEMDPKKFFPWI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCHHHHHHHH
EKITQMEGPNILRLKGIIALKGDDERYVIQGVHMIIEGDHQRAWKDGEKHESRLVFIGRE
HHHHHCCCCCEEEEEEEEEEECCCCEEEEEEEEEEEECCHHHHCCCCCCCCCEEEEEECC
LDAERLKKSFDACQA
CCHHHHHHHHHHHCC
>Mature Secondary Structure 
TNDFWPHRNRRQGEARVTSEAPCSPQGALPQSSGMPIAQVAGQELWPIGLPRAKAPHTS
CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCC
YMEPTIPFSRPGFQGPVISRQAMSDAQTQIPVTVLTGYLGAGKTTLLNRILSENHGRRYA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHCCCCCEEE
VIVNEFGEIGIDNDLIVESDEEIYEMNNGCVCCTVRGDLIRVVEGLMRRPGRFDAIVVET
EEEECCCCCCCCCCEEEECCHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEEEE
TGLADPVPVAQTFFMDDDVRSKTKLDAVVALVDAKHLPLRLKDSKEAEDQIAFADVVVLN
CCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHEEEEEEEEEC
KTDLVTPEELAKVEATIRAINPAAKIHRTTRAGVALSEVLDRGAFDLSRALENDPHFLEG
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECC
HDDHDHHDHDHHDHDGHHHHDHDGHDHHHHDHPSDIHDVTVQSVSLRGGEMDPKKFFPWI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCCCHHHHHHHH
EKITQMEGPNILRLKGIIALKGDDERYVIQGVHMIIEGDHQRAWKDGEKHESRLVFIGRE
HHHHHCCCCCEEEEEEEEEEECCCCEEEEEEEEEEEECCHHHHCCCCCCCCCEEEEEECC
LDAERLKKSFDACQA
CCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]