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The map label for this gene is chvG [H]

Identifier: 13474248

GI number: 13474248

Start: 4036038

End: 4037822

Strand: Reverse

Name: chvG [H]

Synonym: mll5094

Alternate gene names: 13474248

Gene position: 4037822-4036038 (Counterclockwise)

Preceding gene: 13474249

Following gene: 13474247

Centisome position: 57.39

GC content: 64.93

Gene sequence:

>1785_bases
ATGGCAGTGGAAGCACAGCGAACAAGACCGACGGGCGCCGCCAGGCGGCCGTCGCGCATCATGCCGTCCTTCGTCTCGAA
GATCACGGTGCCAATGCGCCGCTTCCTCGGCCACCATATCTTTTCCAGCCTGACGCGGCGCATCCTGTTCCTCAACCTTG
CCGGCCTGGCTGTCCTGGTCACCGGCATCCTCTATCTCAACACTTTCCGCGACGGGCTGATCGATGCCCGCGTCGAAAGC
CTGATGACGCAGGGCGAAATCATCGCCGGCGCGATCGCGGCGTCGGCGACGGTCGAGACCGATTCAATCAGCATCGACCC
GGAAAAGCTGCTTGAGCTGCAGGCCGGCGAAAGCCTGGGACCGGGCTCTGACCAGCTCGACAATCTCGATTTCCCGATCA
ATCCCGAACGTGTCGCGCCGGTGCTGCGGCGGCTGATCTCGCCGACCCGCACGCGGGCTCGCATCTATGACCGCGACGCC
AATCTGCTGCTCGATTCGCGCCATCTCTATTCGCGCGGCCAGATCCTGCGCTACGATCTGCCGCCGGTCGAGGAGGAGCA
GCCCGACCTTGTCGAGCGCGTCCAGAAGTTCATCTTCGACTTCTTCCGCAACACGGACCTGCCGGTCTATCACGAGCAGC
CGGGCGGCAATGGCGCGGCCTTCCCGGAAGTGGTCAAGGCGCTGACCGGCAGCCCGTCGACCATCGTGCGCGTCTCGGAG
CAGGGCGAGCAGATCGTTTCGGTGGCGGTGCCGATCCAGCGCTTCCGTGCCGTTCTCGGCGTCTTGATGCTGTCGACCGA
AGGCGGCGACATCGACAAGATCGTCGCCGCCGAGCGCAAGGCGATCCTGCGCGTCTTCGGCATCGCGGCACTGGTCACCG
CCATCCTGTCGATGCTTTTGGCCTCGACCATCGCCAATCCGCTGCGCCGGCTGTCGGCGGCGGCGGTCAGGGTCCGGCGC
GGCGTCAAGAGCCGCGAGGAAATCCCCGATTTTTCCGACCGGCAGGACGAGATCGGCAACCTGTCGGTCGCGGTGCGCGA
CATGACCAACGCGCTCTATGCGCGCATCGAGGCGATCGAAAGCTTCGCCGCCGACGTGTCGCATGAATTGAAGAACCCGC
TGACCTCGCTGCGCAGCGCGGTGGAGACCCTGCCGCTGGCCAAGAACGACAATTCGCGCAGCCGGCTGATGGACATCATC
CAGCATGACGTGCGCCGGCTGGACCGGCTGATCACCGATATTTCGGACGCCTCCCGTCTCGACGCCGAGCTGGCGCGCGA
GGATGCGGGAACCGTCGACCTGAAGAAATTCATCACCGACCTCGTCGCCGTGTCGCGCGAGACCACGCGCAACAAGAAGG
CTGTCGAGATCGAGCTCAAGGTCGCCAAGCTGCCACAGGGCGTCAAAGGCTATTTCGTCGCCGGCCACGATCTGCGCATC
GGCCAGGTGGTCACCAATCTGATCGAGAATGCACGCTCCTTCGTTCCCGAGGACCATGGCCACATCAGCCTTTCACTGGC
GCGCGCCGGCAAGTTCAACATCCTGACCGTCGACGACAATGGCCCCGGCATCCGCGCCGACAACATCGACCGCATCTTCG
AACGCTTCTATACCGACCGGCCGGCCGGCGAGGCGTTCGGCCAGAATTCGGGCCTTGGCCTGTCGATTTCCAGGCAGATC
GTCGAGGCCCATGGCGGCACGCTGACCGCCGAGAACATCCCCGGCACCAAGCCCGGCGAGATCAAGGGCGCGCGCTTCGT
CGTGACGCTGCCGGCCGAAGCATGA

Upstream 100 bases:

>100_bases
AATAGGGAATAGGCAGTAGGGGTTAGGCAGTAGGGAATCTCAGCCATTTCTCTATTCCCTACTGCCTACTGCCTACTCAC
TAAACAGGGCCTGCTATTCG

Downstream 100 bases:

>100_bases
TCCCACGAAGCGGAGGCCGGTTTCTCGGACGAACGGTGCCGTTCGTCCAGAGATCATGCTTCAGCCAAAGATATAATCGT
GCCTGATCCAGTTGCGCAGC

Product: two-component sensor histidine kinase ExoS

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MAVEAQRTRPTGAARRPSRIMPSFVSKITVPMRRFLGHHIFSSLTRRILFLNLAGLAVLVTGILYLNTFRDGLIDARVES
LMTQGEIIAGAIAASATVETDSISIDPEKLLELQAGESLGPGSDQLDNLDFPINPERVAPVLRRLISPTRTRARIYDRDA
NLLLDSRHLYSRGQILRYDLPPVEEEQPDLVERVQKFIFDFFRNTDLPVYHEQPGGNGAAFPEVVKALTGSPSTIVRVSE
QGEQIVSVAVPIQRFRAVLGVLMLSTEGGDIDKIVAAERKAILRVFGIAALVTAILSMLLASTIANPLRRLSAAAVRVRR
GVKSREEIPDFSDRQDEIGNLSVAVRDMTNALYARIEAIESFAADVSHELKNPLTSLRSAVETLPLAKNDNSRSRLMDII
QHDVRRLDRLITDISDASRLDAELAREDAGTVDLKKFITDLVAVSRETTRNKKAVEIELKVAKLPQGVKGYFVAGHDLRI
GQVVTNLIENARSFVPEDHGHISLSLARAGKFNILTVDDNGPGIRADNIDRIFERFYTDRPAGEAFGQNSGLGLSISRQI
VEAHGGTLTAENIPGTKPGEIKGARFVVTLPAEA

Sequences:

>Translated_594_residues
MAVEAQRTRPTGAARRPSRIMPSFVSKITVPMRRFLGHHIFSSLTRRILFLNLAGLAVLVTGILYLNTFRDGLIDARVES
LMTQGEIIAGAIAASATVETDSISIDPEKLLELQAGESLGPGSDQLDNLDFPINPERVAPVLRRLISPTRTRARIYDRDA
NLLLDSRHLYSRGQILRYDLPPVEEEQPDLVERVQKFIFDFFRNTDLPVYHEQPGGNGAAFPEVVKALTGSPSTIVRVSE
QGEQIVSVAVPIQRFRAVLGVLMLSTEGGDIDKIVAAERKAILRVFGIAALVTAILSMLLASTIANPLRRLSAAAVRVRR
GVKSREEIPDFSDRQDEIGNLSVAVRDMTNALYARIEAIESFAADVSHELKNPLTSLRSAVETLPLAKNDNSRSRLMDII
QHDVRRLDRLITDISDASRLDAELAREDAGTVDLKKFITDLVAVSRETTRNKKAVEIELKVAKLPQGVKGYFVAGHDLRI
GQVVTNLIENARSFVPEDHGHISLSLARAGKFNILTVDDNGPGIRADNIDRIFERFYTDRPAGEAFGQNSGLGLSISRQI
VEAHGGTLTAENIPGTKPGEIKGARFVVTLPAEA
>Mature_593_residues
AVEAQRTRPTGAARRPSRIMPSFVSKITVPMRRFLGHHIFSSLTRRILFLNLAGLAVLVTGILYLNTFRDGLIDARVESL
MTQGEIIAGAIAASATVETDSISIDPEKLLELQAGESLGPGSDQLDNLDFPINPERVAPVLRRLISPTRTRARIYDRDAN
LLLDSRHLYSRGQILRYDLPPVEEEQPDLVERVQKFIFDFFRNTDLPVYHEQPGGNGAAFPEVVKALTGSPSTIVRVSEQ
GEQIVSVAVPIQRFRAVLGVLMLSTEGGDIDKIVAAERKAILRVFGIAALVTAILSMLLASTIANPLRRLSAAAVRVRRG
VKSREEIPDFSDRQDEIGNLSVAVRDMTNALYARIEAIESFAADVSHELKNPLTSLRSAVETLPLAKNDNSRSRLMDIIQ
HDVRRLDRLITDISDASRLDAELAREDAGTVDLKKFITDLVAVSRETTRNKKAVEIELKVAKLPQGVKGYFVAGHDLRIG
QVVTNLIENARSFVPEDHGHISLSLARAGKFNILTVDDNGPGIRADNIDRIFERFYTDRPAGEAFGQNSGLGLSISRQIV
EAHGGTLTAENIPGTKPGEIKGARFVVTLPAEA

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=28.9855072463768, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786600, Length=255, Percent_Identity=27.843137254902, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787894, Length=283, Percent_Identity=28.2685512367491, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=436, Percent_Identity=23.394495412844, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=253, Percent_Identity=27.6679841897233, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=306, Percent_Identity=25.8169934640523, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790861, Length=351, Percent_Identity=26.7806267806268, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=24.901185770751, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=337, Percent_Identity=25.5192878338279, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=31.9327731092437, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=221, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=291, Percent_Identity=28.5223367697594, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=26.3829787234043, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=25.8555133079848, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65171; Mature: 65039

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVEAQRTRPTGAARRPSRIMPSFVSKITVPMRRFLGHHIFSSLTRRILFLNLAGLAVLV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGILYLNTFRDGLIDARVESLMTQGEIIAGAIAASATVETDSISIDPEKLLELQAGESLG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCCCHHHHHHHHCCCCCC
PGSDQLDNLDFPINPERVAPVLRRLISPTRTRARIYDRDANLLLDSRHLYSRGQILRYDL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHEECCCCEEECCHHHHCCCCEEEECC
PPVEEEQPDLVERVQKFIFDFFRNTDLPVYHEQPGGNGAAFPEVVKALTGSPSTIVRVSE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEEECC
QGEQIVSVAVPIQRFRAVLGVLMLSTEGGDIDKIVAAERKAILRVFGIAALVTAILSMLL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASTIANPLRRLSAAAVRVRRGVKSREEIPDFSDRQDEIGNLSVAVRDMTNALYARIEAIE
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SFAADVSHELKNPLTSLRSAVETLPLAKNDNSRSRLMDIIQHDVRRLDRLITDISDASRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAELAREDAGTVDLKKFITDLVAVSRETTRNKKAVEIELKVAKLPQGVKGYFVAGHDLRI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCCHH
GQVVTNLIENARSFVPEDHGHISLSLARAGKFNILTVDDNGPGIRADNIDRIFERFYTDR
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC
PAGEAFGQNSGLGLSISRQIVEAHGGTLTAENIPGTKPGEIKGARFVVTLPAEA
CCCHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
AVEAQRTRPTGAARRPSRIMPSFVSKITVPMRRFLGHHIFSSLTRRILFLNLAGLAVLV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGILYLNTFRDGLIDARVESLMTQGEIIAGAIAASATVETDSISIDPEKLLELQAGESLG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEECCCCCCCHHHHHHHHCCCCCC
PGSDQLDNLDFPINPERVAPVLRRLISPTRTRARIYDRDANLLLDSRHLYSRGQILRYDL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHEECCCCEEECCHHHHCCCCEEEECC
PPVEEEQPDLVERVQKFIFDFFRNTDLPVYHEQPGGNGAAFPEVVKALTGSPSTIVRVSE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCEEEEECC
QGEQIVSVAVPIQRFRAVLGVLMLSTEGGDIDKIVAAERKAILRVFGIAALVTAILSMLL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASTIANPLRRLSAAAVRVRRGVKSREEIPDFSDRQDEIGNLSVAVRDMTNALYARIEAIE
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SFAADVSHELKNPLTSLRSAVETLPLAKNDNSRSRLMDIIQHDVRRLDRLITDISDASRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAELAREDAGTVDLKKFITDLVAVSRETTRNKKAVEIELKVAKLPQGVKGYFVAGHDLRI
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEECCCCHH
GQVVTNLIENARSFVPEDHGHISLSLARAGKFNILTVDDNGPGIRADNIDRIFERFYTDR
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC
PAGEAFGQNSGLGLSISRQIVEAHGGTLTAENIPGTKPGEIKGARFVVTLPAEA
CCCHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]