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The map label for this gene is yggW [C]

Identifier: 13473883

GI number: 13473883

Start: 3669405

End: 3670583

Strand: Direct

Name: yggW [C]

Synonym: mlr4627

Alternate gene names: 13473883

Gene position: 3669405-3670583 (Clockwise)

Preceding gene: 13473882

Following gene: 13473884

Centisome position: 52.15

GC content: 67.18

Gene sequence:

>1179_bases
ATGACTGGACCTGGCATGACCATGCCGCTCGACCGCAGCCCCGGCTTTGGCGTCTACATCCATTGGCCGTTCTGCGCGGC
CAAGTGCCCCTATTGCGACTTCAACAGCCATGTCCGCCACCAGCCGGTGGACCAGGAGCGCTTTGCCGCCGCCTTCGAGG
CGGAACTGGCGACGATGCGTGAGCGCACCGGGCCGCGCGAGGTGACCAGCATTTTCCTCGGCGGCGGCACGCCGTCGCTG
ATGAAGCCGGAAACCGTGGCCAGGGTCCTGGACGCCGTGGCGAAGAACTGGACGGTACCGGACGGCATCGAGGTGACGCT
TGAAGCTAACCCGTCCTCGGTCGAAGCCGAACGCTTTCGCGGCTATCGGGCGGCGGGCGTCAACCGCGTCTCGCTCGGCG
TGCAGGCGCTCAACGACAAGGATTTGCGCTTCCTCGGCCGCCTGCACAATGTCGAAGAGGCGCTGCACGCCATCGGGCTC
GCGCGCGAAATCTTTCCGCGCCTGTCCTTCGACCTGATCTACGCCCGGCCCGGCCAGACGCCGGAGGCCTGGGCAGCCGA
GCTCGAACAGGCGATCGGCCACGCTGCCGACCATCTCTCGCTCTACCAGCTGACCATCGAGGAAGGCACGCCCTTCCACG
CGCTGCATGCGGCGAAGAAATTCATCATCCCTGACAACGACCACGCCGCCGACCTCTATGCGTTGACGCAGGAGACTACG
TCCGCGCATGGCCTGCCGGCCTATGAGATTTCCAACCACGCCAGGCCTGGCGCCGAAAGCCGGCACAATCTGACCTACTG
GCGCTATGGCGAATATGTCGGCGTCGGCCCCGGCGCGCATGGGCGCTTCGTCGAGCATGGCCGCCGCACGGTGACGATCG
CCGAAAGGATGCCGGAAACCTGGGCCAACCTCGTCGAGGCCAAGGGCCATGGTGTCACCGGGGGCGAGATCCTGACGCGC
TCGGAAGAGGCCGACGAATTCCTGCTGATGGGGCTGAGGCTGGCCGAGGGCATCGACCTTGCGCGCTACGAGGCCTTTTC
CGGCCGCGGCCTGTCGAGCGCCCGGCTGTCGGTGCTGCAGGGCGAGGGTCTGGTGGCGCCGATCGGCAATGCGCGGCTGC
GCGCCACACCGGCCGGCATGATCGTTCTCGACGCCGTGGTGGCGGATCTGGCGCGCTAA

Upstream 100 bases:

>100_bases
ACGGCTGGAAACCCGGCCAGGCCGCGGCGCTCTCACATCGCGCCCGTGCTTTCCAGAAATTCGCGCAAGCACGGTTGGAT
CTGCCGAGATTGGGCTCGGC

Downstream 100 bases:

>100_bases
CCTTTGAAAAACGTTCTCTTCGTCTGCAGTCAGAACCGCTTGCGCAGCCCGACCGCCGAGCAGGTGTTTTCAACGCGCCG
GGATATCGAGGTCGCCTCGG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTGPGMTMPLDRSPGFGVYIHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFEAELATMRERTGPREVTSIFLGGGTPSL
MKPETVARVLDAVAKNWTVPDGIEVTLEANPSSVEAERFRGYRAAGVNRVSLGVQALNDKDLRFLGRLHNVEEALHAIGL
AREIFPRLSFDLIYARPGQTPEAWAAELEQAIGHAADHLSLYQLTIEEGTPFHALHAAKKFIIPDNDHAADLYALTQETT
SAHGLPAYEISNHARPGAESRHNLTYWRYGEYVGVGPGAHGRFVEHGRRTVTIAERMPETWANLVEAKGHGVTGGEILTR
SEEADEFLLMGLRLAEGIDLARYEAFSGRGLSSARLSVLQGEGLVAPIGNARLRATPAGMIVLDAVVADLAR

Sequences:

>Translated_392_residues
MTGPGMTMPLDRSPGFGVYIHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFEAELATMRERTGPREVTSIFLGGGTPSL
MKPETVARVLDAVAKNWTVPDGIEVTLEANPSSVEAERFRGYRAAGVNRVSLGVQALNDKDLRFLGRLHNVEEALHAIGL
AREIFPRLSFDLIYARPGQTPEAWAAELEQAIGHAADHLSLYQLTIEEGTPFHALHAAKKFIIPDNDHAADLYALTQETT
SAHGLPAYEISNHARPGAESRHNLTYWRYGEYVGVGPGAHGRFVEHGRRTVTIAERMPETWANLVEAKGHGVTGGEILTR
SEEADEFLLMGLRLAEGIDLARYEAFSGRGLSSARLSVLQGEGLVAPIGNARLRATPAGMIVLDAVVADLAR
>Mature_391_residues
TGPGMTMPLDRSPGFGVYIHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFEAELATMRERTGPREVTSIFLGGGTPSLM
KPETVARVLDAVAKNWTVPDGIEVTLEANPSSVEAERFRGYRAAGVNRVSLGVQALNDKDLRFLGRLHNVEEALHAIGLA
REIFPRLSFDLIYARPGQTPEAWAAELEQAIGHAADHLSLYQLTIEEGTPFHALHAAKKFIIPDNDHAADLYALTQETTS
AHGLPAYEISNHARPGAESRHNLTYWRYGEYVGVGPGAHGRFVEHGRRTVTIAERMPETWANLVEAKGHGVTGGEILTRS
EEADEFLLMGLRLAEGIDLARYEAFSGRGLSSARLSVLQGEGLVAPIGNARLRATPAGMIVLDAVVADLAR

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=300, Percent_Identity=42.6666666666667, Blast_Score=248, Evalue=8e-66,
Organism=Escherichia coli, GI1789325, Length=339, Percent_Identity=36.5781710914454, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI87082341, Length=245, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42793; Mature: 42662

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPGMTMPLDRSPGFGVYIHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFEAELATMR
CCCCCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERTGPREVTSIFLGGGTPSLMKPETVARVLDAVAKNWTVPDGIEVTLEANPSSVEAERFR
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHC
GYRAAGVNRVSLGVQALNDKDLRFLGRLHNVEEALHAIGLAREIFPRLSFDLIYARPGQT
CHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
PEAWAAELEQAIGHAADHLSLYQLTIEEGTPFHALHAAKKFIIPDNDHAADLYALTQETT
HHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHEECCCCCCCHHHEEEHHHCC
SAHGLPAYEISNHARPGAESRHNLTYWRYGEYVGVGPGAHGRFVEHGRRTVTIAERMPET
CCCCCCCHHHCCCCCCCCCCCCCCEEEECCCEEECCCCCCCHHHHCCCEEEEHHHHCCHH
WANLVEAKGHGVTGGEILTRSEEADEFLLMGLRLAEGIDLARYEAFSGRGLSSARLSVLQ
HHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHEEEE
GEGLVAPIGNARLRATPAGMIVLDAVVADLAR
CCCCEEECCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TGPGMTMPLDRSPGFGVYIHWPFCAAKCPYCDFNSHVRHQPVDQERFAAAFEAELATMR
CCCCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
ERTGPREVTSIFLGGGTPSLMKPETVARVLDAVAKNWTVPDGIEVTLEANPSSVEAERFR
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHC
GYRAAGVNRVSLGVQALNDKDLRFLGRLHNVEEALHAIGLAREIFPRLSFDLIYARPGQT
CHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
PEAWAAELEQAIGHAADHLSLYQLTIEEGTPFHALHAAKKFIIPDNDHAADLYALTQETT
HHHHHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHEECCCCCCCHHHEEEHHHCC
SAHGLPAYEISNHARPGAESRHNLTYWRYGEYVGVGPGAHGRFVEHGRRTVTIAERMPET
CCCCCCCHHHCCCCCCCCCCCCCCEEEECCCEEECCCCCCCHHHHCCCEEEEHHHHCCHH
WANLVEAKGHGVTGGEILTRSEEADEFLLMGLRLAEGIDLARYEAFSGRGLSSARLSVLQ
HHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHEEEE
GEGLVAPIGNARLRATPAGMIVLDAVVADLAR
CCCCEEECCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]