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The map label for this gene is yggV [C]

Identifier: 13473882

GI number: 13473882

Start: 3668746

End: 3669408

Strand: Direct

Name: yggV [C]

Synonym: mlr4626

Alternate gene names: 13473882

Gene position: 3668746-3669408 (Clockwise)

Preceding gene: 13473881

Following gene: 13473883

Centisome position: 52.14

GC content: 64.25

Gene sequence:

>663_bases
ATGCATACACTTGATGGCAAGAAGATCGTCGTCGCCAGCCACAATGCCGGCAAGCTGCGCGAATTCGCCGACCTGATGGG
GCCGTTTGGCTTCGAGGCGAAGTCGGCCAAGGACTACGGTCTGCCTGAACCGGACGAGACCGGCACGACCTTCGAGGAAA
ACGCCTACATCAAGGCGCTGGCCGCCGCGAAGGCGACCGGCCTGCCGGCGCTGTCGGACGATTCCGGCCTGTGCGTCGAT
GCGCTCGACGGCGCGCCCGGCGTCTACACCGCCAACTGGGCCGAAACGCCTGACGGCAGCAGAGATTTCGCCATGGCCAT
GCAGCGTACAGAAGTGGCTTTGCAGGAAGTCGGCGCCGCCTCGGCCGAACAGCGCAAGGGCCGCTTCGTCGCCGTCATTT
GTCTCGCCTTTCCCGACGGGGCGGCCGAATATTATCGCGGCGAGGCCGAAGGCACGCTGGTCTGGCCGCCGCGTGGCGAG
CTCGGCTTCGGTTATGATCCGGTGTTCTTGCCCAATGGTTTCGACAAGACGTTTGGCGAGATGAGCGCTGAGGAAAAGCA
CGGCTGGAAACCCGGCCAGGCCGCGGCGCTCTCACATCGCGCCCGTGCTTTCCAGAAATTCGCGCAAGCACGGTTGGATC
TGCCGAGATTGGGCTCGGCATGA

Upstream 100 bases:

>100_bases
AAAGCGAATTCGAATGGCCGCAAGGCGGCCGTTCGCTCTATATACGCGACCCCTCGGGCAATTCGATCGAGTTCGCCGAG
CCGAGAATTTGGGGCCTTTG

Downstream 100 bases:

>100_bases
CTGGACCTGGCATGACCATGCCGCTCGACCGCAGCCCCGGCTTTGGCGTCTACATCCATTGGCCGTTCTGCGCGGCCAAG
TGCCCCTATTGCGACTTCAA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MHTLDGKKIVVASHNAGKLREFADLMGPFGFEAKSAKDYGLPEPDETGTTFEENAYIKALAAAKATGLPALSDDSGLCVD
ALDGAPGVYTANWAETPDGSRDFAMAMQRTEVALQEVGAASAEQRKGRFVAVICLAFPDGAAEYYRGEAEGTLVWPPRGE
LGFGYDPVFLPNGFDKTFGEMSAEEKHGWKPGQAAALSHRARAFQKFAQARLDLPRLGSA

Sequences:

>Translated_220_residues
MHTLDGKKIVVASHNAGKLREFADLMGPFGFEAKSAKDYGLPEPDETGTTFEENAYIKALAAAKATGLPALSDDSGLCVD
ALDGAPGVYTANWAETPDGSRDFAMAMQRTEVALQEVGAASAEQRKGRFVAVICLAFPDGAAEYYRGEAEGTLVWPPRGE
LGFGYDPVFLPNGFDKTFGEMSAEEKHGWKPGQAAALSHRARAFQKFAQARLDLPRLGSA
>Mature_220_residues
MHTLDGKKIVVASHNAGKLREFADLMGPFGFEAKSAKDYGLPEPDETGTTFEENAYIKALAAAKATGLPALSDDSGLCVD
ALDGAPGVYTANWAETPDGSRDFAMAMQRTEVALQEVGAASAEQRKGRFVAVICLAFPDGAAEYYRGEAEGTLVWPPRGE
LGFGYDPVFLPNGFDKTFGEMSAEEKHGWKPGQAAALSHRARAFQKFAQARLDLPRLGSA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=206, Percent_Identity=37.8640776699029, Blast_Score=125, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19920712, Length=208, Percent_Identity=31.7307692307692, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_RHILO (Q98DN4)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105450.1
- ProteinModelPortal:   Q98DN4
- SMR:   Q98DN4
- GeneID:   1228111
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr4626
- NMPDR:   fig|266835.1.peg.3554
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- ProtClustDB:   PRK00120
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 23521; Mature: 23521

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLDGKKIVVASHNAGKLREFADLMGPFGFEAKSAKDYGLPEPDETGTTFEENAYIKAL
CCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AAAKATGLPALSDDSGLCVDALDGAPGVYTANWAETPDGSRDFAMAMQRTEVALQEVGAA
HHHHHCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SAEQRKGRFVAVICLAFPDGAAEYYRGEAEGTLVWPPRGELGFGYDPVFLPNGFDKTFGE
CHHHHCCCEEEEEEEECCCCHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCCCHHHHHH
MSAEEKHGWKPGQAAALSHRARAFQKFAQARLDLPRLGSA
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHTLDGKKIVVASHNAGKLREFADLMGPFGFEAKSAKDYGLPEPDETGTTFEENAYIKAL
CCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
AAAKATGLPALSDDSGLCVDALDGAPGVYTANWAETPDGSRDFAMAMQRTEVALQEVGAA
HHHHHCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SAEQRKGRFVAVICLAFPDGAAEYYRGEAEGTLVWPPRGELGFGYDPVFLPNGFDKTFGE
CHHHHCCCEEEEEEEECCCCHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCCCHHHHHH
MSAEEKHGWKPGQAAALSHRARAFQKFAQARLDLPRLGSA
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968