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The map label for this gene is dppE [H]

Identifier: 13473817

GI number: 13473817

Start: 3610043

End: 3611674

Strand: Reverse

Name: dppE [H]

Synonym: mll4539

Alternate gene names: 13473817

Gene position: 3611674-3610043 (Counterclockwise)

Preceding gene: 13473818

Following gene: 13473814

Centisome position: 51.33

GC content: 64.71

Gene sequence:

>1632_bases
ATGCTGACCGACCGCAAACTGCACCCGCGGGCCAAGCCCGTCGCCGAGGATTTCAAAACCGGCGCCATCAGCCGCCGCGA
ATATCTGGCGCTGATGGCCGGCCTCGGCGTCAGCGCCGCCGGCGCGTTTGCGCTCGGCGGCCTCGCCCCGACCCCGGCCC
GCGCGGCCGAGCCGAAGAAGGGCGGCACCTTGCGCGTCGCCATGAACGTCAAGGGTTTCAAGGACCCACGCACCTTCGAC
GGCGTCGAAATGTCCAACGTCGCCCGCCACTGCAACGAATATCTGGTGCGCTGGAACACCGATTTTTCCTTCGAGCCCTG
GCTGCTGGAAAAATGGGAGATGAGCGATGACGCCAAGACGCTGACGCTGCATGTGCGCAAAGGCGTCACCTGGTCGAACG
GCGACGCCTTCAACGCCGACGATGTCGTCCACAACCTCACCCGCTGGTGCGAGGCCGGCGTGGCCGGCAATTCGGTCGCC
GCGCGCATGGGCGCGCTGGTCAATGCCGACACCAAGAAGGCGGTCGATGGCGGCATCGAGAAGGTCGACGACTACACGAT
CAAGCTCAACCTGCCGAAGCCCGACATTTCGCTGATCGCCGGCATGGCCGACTATCCCGCGCTGATCATGCACCGCTCCT
ATGCCGGCGACGGCGACCCCATGAAGGCGCTGGCCATCACCACCGGCCCCTGCGAACTGGTGAAATGGGACGCCGAGACG
GGCGCGCAGGTGAAGCGCAAGGACAAGCCCTGGTGGAAGGGCGAATTCCATCTGGATGGCATCCAGTGGATCGACTACGG
CTCCGACCCCAACGCCATGCTGTCGGCCTTCGAATCCGGCGAGATCGACACTGACCACGAAACCGCCTCCGACGCCGTCT
CGCAGACCGACAAGATGGGGCTTAAAAATTCCGAGATCGCCACCGGCTCGACCATCGTCGCCCGCTTCAACATCGGCAAT
GCGCCCTATGACGACGTCAAGGTCCGCCGTGCCGCCCAGCTCGCCGTCGACAATGCCGCCGTGCTCGCGCTCGGCCTCGG
AGGCCGCGGCAAGCCCGCCGACAACCACCATGTCGGCCCCATGCACCCCGAATATGCCGATATCGGCCCAGCCAAGCGCG
ACGTGGAGGAAGCCAAGAACCTGCTCGCCGCCTCCGCCAAGCCGGACCATGAATATGAGCTGATCTCGGTCGACGTCGAA
TGGCAGAAGAGCACCGGCGACGCGATATCAGCGCAGATGCGCGAGGCCGGCCTCAAGATCAAGCGCACCGTGCTGCCCGC
CGCCACCTTCTGGAACGACTGGAGCAAATATCCCTTCTCCTGCACCGAATGGCTCGGCCGCTCGCTCGGCGTCCAGGTGC
TGGCGCTGGCGTATAAATCGGGCGCCGCCTGGAACGAAAGCGCCTATGCCAGCAAGGAGTTCGACGACCTGCTCGACAAG
GCGCTGGCGACGCCCGACGCCAAGGCGCGCAAGGAGATCATGGCCGGCATCGAGAAGAATTTGCGCGACAGCGGCATCAT
CATCCAACCCTACTGGCGCTCGGTGTATCGGACCTACCGCAAGGGCGTCGAGGGCTGCGAACAGCACCAGGCACTGGAGC
AGCACTTTGAGAAGGTTTGGATCGAAAGCTGA

Upstream 100 bases:

>100_bases
CTCGCGTAGGCGATTCGCCGGGACGAGTCTGATTCCGTGCATGTCCCAAAGCGCTTTTGGGCGGCCTGCACCAACAAAAG
AGGGAACGACGATGAAATTC

Downstream 100 bases:

>100_bases
GGCGCGGCGCTTCTTACCTTCTCCCCTTGTGGGGTGAGGGGCGGTCCGCGTCAGCGGACGGAAAGCCAACTGCTTGGCTT
TCCGAGCCTCGAACGCCCTG

Product: dipeptide ABC transporter (dipeptide-binding protein)

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MLTDRKLHPRAKPVAEDFKTGAISRREYLALMAGLGVSAAGAFALGGLAPTPARAAEPKKGGTLRVAMNVKGFKDPRTFD
GVEMSNVARHCNEYLVRWNTDFSFEPWLLEKWEMSDDAKTLTLHVRKGVTWSNGDAFNADDVVHNLTRWCEAGVAGNSVA
ARMGALVNADTKKAVDGGIEKVDDYTIKLNLPKPDISLIAGMADYPALIMHRSYAGDGDPMKALAITTGPCELVKWDAET
GAQVKRKDKPWWKGEFHLDGIQWIDYGSDPNAMLSAFESGEIDTDHETASDAVSQTDKMGLKNSEIATGSTIVARFNIGN
APYDDVKVRRAAQLAVDNAAVLALGLGGRGKPADNHHVGPMHPEYADIGPAKRDVEEAKNLLAASAKPDHEYELISVDVE
WQKSTGDAISAQMREAGLKIKRTVLPAATFWNDWSKYPFSCTEWLGRSLGVQVLALAYKSGAAWNESAYASKEFDDLLDK
ALATPDAKARKEIMAGIEKNLRDSGIIIQPYWRSVYRTYRKGVEGCEQHQALEQHFEKVWIES

Sequences:

>Translated_543_residues
MLTDRKLHPRAKPVAEDFKTGAISRREYLALMAGLGVSAAGAFALGGLAPTPARAAEPKKGGTLRVAMNVKGFKDPRTFD
GVEMSNVARHCNEYLVRWNTDFSFEPWLLEKWEMSDDAKTLTLHVRKGVTWSNGDAFNADDVVHNLTRWCEAGVAGNSVA
ARMGALVNADTKKAVDGGIEKVDDYTIKLNLPKPDISLIAGMADYPALIMHRSYAGDGDPMKALAITTGPCELVKWDAET
GAQVKRKDKPWWKGEFHLDGIQWIDYGSDPNAMLSAFESGEIDTDHETASDAVSQTDKMGLKNSEIATGSTIVARFNIGN
APYDDVKVRRAAQLAVDNAAVLALGLGGRGKPADNHHVGPMHPEYADIGPAKRDVEEAKNLLAASAKPDHEYELISVDVE
WQKSTGDAISAQMREAGLKIKRTVLPAATFWNDWSKYPFSCTEWLGRSLGVQVLALAYKSGAAWNESAYASKEFDDLLDK
ALATPDAKARKEIMAGIEKNLRDSGIIIQPYWRSVYRTYRKGVEGCEQHQALEQHFEKVWIES
>Mature_543_residues
MLTDRKLHPRAKPVAEDFKTGAISRREYLALMAGLGVSAAGAFALGGLAPTPARAAEPKKGGTLRVAMNVKGFKDPRTFD
GVEMSNVARHCNEYLVRWNTDFSFEPWLLEKWEMSDDAKTLTLHVRKGVTWSNGDAFNADDVVHNLTRWCEAGVAGNSVA
ARMGALVNADTKKAVDGGIEKVDDYTIKLNLPKPDISLIAGMADYPALIMHRSYAGDGDPMKALAITTGPCELVKWDAET
GAQVKRKDKPWWKGEFHLDGIQWIDYGSDPNAMLSAFESGEIDTDHETASDAVSQTDKMGLKNSEIATGSTIVARFNIGN
APYDDVKVRRAAQLAVDNAAVLALGLGGRGKPADNHHVGPMHPEYADIGPAKRDVEEAKNLLAASAKPDHEYELISVDVE
WQKSTGDAISAQMREAGLKIKRTVLPAATFWNDWSKYPFSCTEWLGRSLGVQVLALAYKSGAAWNESAYASKEFDDLLDK
ALATPDAKARKEIMAGIEKNLRDSGIIIQPYWRSVYRTYRKGVEGCEQHQALEQHFEKVWIES

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=464, Percent_Identity=24.3534482758621, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787052, Length=486, Percent_Identity=24.4855967078189, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1787495, Length=548, Percent_Identity=22.4452554744526, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787551, Length=333, Percent_Identity=25.2252252252252, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789397, Length=494, Percent_Identity=21.2550607287449, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59597; Mature: 59597

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDRKLHPRAKPVAEDFKTGAISRREYLALMAGLGVSAAGAFALGGLAPTPARAAEPKK
CCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCC
GGTLRVAMNVKGFKDPRTFDGVEMSNVARHCNEYLVRWNTDFSFEPWLLEKWEMSDDAKT
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCHHHCCCCCCCCEE
LTLHVRKGVTWSNGDAFNADDVVHNLTRWCEAGVAGNSVAARMGALVNADTKKAVDGGIE
EEEEEECCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCC
KVDDYTIKLNLPKPDISLIAGMADYPALIMHRSYAGDGDPMKALAITTGPCELVKWDAET
CCCCEEEEEECCCCCHHHHHCCCCCCHHHEECCCCCCCCCCEEEEEECCCCEEEEECCCC
GAQVKRKDKPWWKGEFHLDGIQWIDYGSDPNAMLSAFESGEIDTDHETASDAVSQTDKMG
CCHHHCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
LKNSEIATGSTIVARFNIGNAPYDDVKVRRAAQLAVDNAAVLALGLGGRGKPADNHHVGP
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
MHPEYADIGPAKRDVEEAKNLLAASAKPDHEYELISVDVEWQKSTGDAISAQMREAGLKI
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEE
KRTVLPAATFWNDWSKYPFSCTEWLGRSLGVQVLALAYKSGAAWNESAYASKEFDDLLDK
EEHHCCHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALATPDAKARKEIMAGIEKNLRDSGIIIQPYWRSVYRTYRKGVEGCEQHQALEQHFEKVW
HHCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IES
CCC
>Mature Secondary Structure
MLTDRKLHPRAKPVAEDFKTGAISRREYLALMAGLGVSAAGAFALGGLAPTPARAAEPKK
CCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCC
GGTLRVAMNVKGFKDPRTFDGVEMSNVARHCNEYLVRWNTDFSFEPWLLEKWEMSDDAKT
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCHHHCCCCCCCCEE
LTLHVRKGVTWSNGDAFNADDVVHNLTRWCEAGVAGNSVAARMGALVNADTKKAVDGGIE
EEEEEECCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHCCCC
KVDDYTIKLNLPKPDISLIAGMADYPALIMHRSYAGDGDPMKALAITTGPCELVKWDAET
CCCCEEEEEECCCCCHHHHHCCCCCCHHHEECCCCCCCCCCEEEEEECCCCEEEEECCCC
GAQVKRKDKPWWKGEFHLDGIQWIDYGSDPNAMLSAFESGEIDTDHETASDAVSQTDKMG
CCHHHCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
LKNSEIATGSTIVARFNIGNAPYDDVKVRRAAQLAVDNAAVLALGLGGRGKPADNHHVGP
CCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
MHPEYADIGPAKRDVEEAKNLLAASAKPDHEYELISVDVEWQKSTGDAISAQMREAGLKI
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEE
KRTVLPAATFWNDWSKYPFSCTEWLGRSLGVQVLALAYKSGAAWNESAYASKEFDDLLDK
EEHHCCHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALATPDAKARKEIMAGIEKNLRDSGIIIQPYWRSVYRTYRKGVEGCEQHQALEQHFEKVW
HHCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IES
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]