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The map label for this gene is dnaQ [H]

Identifier: 13473785

GI number: 13473785

Start: 3576222

End: 3576944

Strand: Direct

Name: dnaQ [H]

Synonym: mlr4495

Alternate gene names: 13473785

Gene position: 3576222-3576944 (Clockwise)

Preceding gene: 13473784

Following gene: 13473793

Centisome position: 50.83

GC content: 65.15

Gene sequence:

>723_bases
ATGCGCGAGATCATCTTCGATACGGAAACCACCGGCCTTGATTCGCGCGACGACCGCGTGATCGAGTTGGGCGGCGTCGA
ACTCGTCAACCGTTTCCCGACCGGCAGGACGTTCCATCACTATATCAACCCGCAAGGCCGCGCGATCCACGAGGAGGCGC
AGGCGGTGCACGGCATCAGCGCGGCGGATCTCGCGGGCAAGCCGACCTTTGCCGAAATCGCTGAGGAATGGCTGACCTTC
ACCGATGGCGCCAAGCTGGTCGCGCACAACGCCACTTTCGACATCGGCTTCCTCAATGTCGAATTCGGCCGGCTCGGCCA
TCCCGTCGTCGATCCCGGCCGTGTCGTCGACACGCTGGCGCTGGCGCGCCGCAAGCATCCGATGGGTCCCAATTCGCTCG
ATGCGCTCTGCCGGCGCTACGGCATCGACAATACGAAGCGCACCAAGCACGGCGCGCTGCTCGATTCCGAATTGCTGGCC
GAGGTCTATATCGAGCTGATCGGCGGCAAGCAGGCGGCGCTCATCCTCGACAGCGCCACCGCGCCGGCACAGGGCGAGAA
TGTCAGGCACATCGAGATCATCGTCGCAGAGCGCCCGAGGCCGCTGCTGCCGCGCCTGACCGAAGCGGAGCGCGCCGCGC
ATGCCGCCATGGTCGCCACGCTCGGCGAAAAGGCGCTCTGGCTGAAAGCCAACTCCTCCGAAAAGAGCATCGCGGCGTCG
TAA

Upstream 100 bases:

>100_bases
TCCGGGGACAAAGGGGCTCCTGACGGCGGGCTGTCAGCATTGCCCATTGCCATTTTGTTCCGGTCTCGTGATTCTGCTCG
CCCAGGAGCAAACTGATTCG

Downstream 100 bases:

>100_bases
GACTCAATACGGCCACTCACCCCGGCCAAGCGCCGCGATCGCCGCGATGATGCGGCTAAAAGCTTCCGCCGCTGCCGGCA
CCGTGGTGCGGGCGCGCAGG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MREIIFDTETTGLDSRDDRVIELGGVELVNRFPTGRTFHHYINPQGRAIHEEAQAVHGISAADLAGKPTFAEIAEEWLTF
TDGAKLVAHNATFDIGFLNVEFGRLGHPVVDPGRVVDTLALARRKHPMGPNSLDALCRRYGIDNTKRTKHGALLDSELLA
EVYIELIGGKQAALILDSATAPAQGENVRHIEIIVAERPRPLLPRLTEAERAAHAAMVATLGEKALWLKANSSEKSIAAS

Sequences:

>Translated_240_residues
MREIIFDTETTGLDSRDDRVIELGGVELVNRFPTGRTFHHYINPQGRAIHEEAQAVHGISAADLAGKPTFAEIAEEWLTF
TDGAKLVAHNATFDIGFLNVEFGRLGHPVVDPGRVVDTLALARRKHPMGPNSLDALCRRYGIDNTKRTKHGALLDSELLA
EVYIELIGGKQAALILDSATAPAQGENVRHIEIIVAERPRPLLPRLTEAERAAHAAMVATLGEKALWLKANSSEKSIAAS
>Mature_240_residues
MREIIFDTETTGLDSRDDRVIELGGVELVNRFPTGRTFHHYINPQGRAIHEEAQAVHGISAADLAGKPTFAEIAEEWLTF
TDGAKLVAHNATFDIGFLNVEFGRLGHPVVDPGRVVDTLALARRKHPMGPNSLDALCRRYGIDNTKRTKHGALLDSELLA
EVYIELIGGKQAALILDSATAPAQGENVRHIEIIVAERPRPLLPRLTEAERAAHAAMVATLGEKALWLKANSSEKSIAAS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=44.5378151260504, Blast_Score=183, Evalue=8e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26149; Mature: 26149

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIIFDTETTGLDSRDDRVIELGGVELVNRFPTGRTFHHYINPQGRAIHEEAQAVHGIS
CCCEEECCCCCCCCCCCCCEEEECCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCC
AADLAGKPTFAEIAEEWLTFTDGAKLVAHNATFDIGFLNVEFGRLGHPVVDPGRVVDTLA
HHHCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
LARRKHPMGPNSLDALCRRYGIDNTKRTKHGALLDSELLAEVYIELIGGKQAALILDSAT
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCC
APAQGENVRHIEIIVAERPRPLLPRLTEAERAAHAAMVATLGEKALWLKANSSEKSIAAS
CCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MREIIFDTETTGLDSRDDRVIELGGVELVNRFPTGRTFHHYINPQGRAIHEEAQAVHGIS
CCCEEECCCCCCCCCCCCCEEEECCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHCCCC
AADLAGKPTFAEIAEEWLTFTDGAKLVAHNATFDIGFLNVEFGRLGHPVVDPGRVVDTLA
HHHCCCCCCHHHHHHHHHHHCCCCEEEEECCEEEEEEEEEECCCCCCCCCCCHHHHHHHH
LARRKHPMGPNSLDALCRRYGIDNTKRTKHGALLDSELLAEVYIELIGGKQAALILDSAT
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCC
APAQGENVRHIEIIVAERPRPLLPRLTEAERAAHAAMVATLGEKALWLKANSSEKSIAAS
CCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]