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The map label for this gene is mnmG

Identifier: 13473775

GI number: 13473775

Start: 3563695

End: 3565566

Strand: Reverse

Name: mnmG

Synonym: mll4482

Alternate gene names: 13473775

Gene position: 3565566-3563695 (Counterclockwise)

Preceding gene: 13473776

Following gene: 13473774

Centisome position: 50.68

GC content: 64.8

Gene sequence:

>1872_bases
ATGACCGATCACTATGATGTGGTTGTGGTGGGCGGCGGCCATGCGGGATGCGAGGCGGCCAGTGCCGCCGCGCGCGCCGG
CGCAAAAACCGCGCTGGTGACGCTGCGCTTCGATACGATCGGCGTGATGTCGTGCAATCCGGCGATTGGCGGGCTCGGTA
AGGGCCATCTGGTCCGCGAGATCGACGCCATGGACGGGCTGATGGGTCGGGTGGCGGATGCCGCCGGGATCCAGTTCCGT
CTGCTCAACCGCCGCAAGGGTCCGGCGGTGCGCGGGCCACGCACGCAGGCCGATCGAAAGCTCTATCGCCTTGCTATGCA
GGAAGCGATTCGGCAGCAGAACGATCTCGACGTGGTCGAGGGCGAGGTGCTGGATTTCGAGATCAACGAAGGACGGATCA
CTGCTGTCCTCCTGGCCGGCGGCCGGAGGCTTGCCTGCGGCGCCGTGGTCCTGACGACAGGCACTTTCCTGCGCGGCCTC
ATTCATATTGGCGAGAAGAAGATCGTCGCCGGCCGCATGAACGAGCAGGCGAGCCTTGGTCTGTCGGCGACCATGGACCG
CGCCGGCTTCAAGCTCGGCCGCCTGAAGACCGGCACGCCACCGCGGCTGGATGGAAAGACCATCGACTGGGCGTCGCTGG
AAAGCCAGGCTGCGGACGAGGATCCGGTGCCGTTCTCACTGATGAGCGACCGCATCACCACACCGCAGATCGAGTGCGGC
ATCACGCGCACGACATCAGCCACACATGAGCTGATCCGCGCCAATCTCGGGCGCTCCGCCATGTATTCCGGATCGATCGA
AGGCGTCGGGCCGCGCTATTGCCCGTCGATCGAGGACAAGATCGTCAAGTTCGGCGACCGCGACGGCCACCAGATCTTTC
TCGAGCCAGAGGGGCTCGACGACGACACGGTCTATCCCAATGGGATTTCGACCTCGCTGCCGCAGGATGTGCAGCTCGAG
ATCCTTAAGACAATTCCGGGGCTGGAGCGCGCGACCATGCTGCAGCCCGGCTATGCTATCGAGTATGATCATGTCGATCC
GCGCGAGCTGCATCAGACGCTGGAGACCAAGCGCATCGCTGGCCTCTTTCTCGCTGGGCAGATCAACGGCACCACGGGCT
ATGAGGAGGCGGCTGGCCAGGGCTTGCTCGCTGGCCTCAACGCGGCGCGGCGGGCAGCGGGCGGCGAGCAGATCGTGCTG
AGCCGCACCGAGGCCTATATCGGCGTGATGGTCGACGATTTGACCAGCCGCGGCATCAGCGAACCCTACCGCATGTTCAC
CTCGCGCGCCGAATTCCGGCTGTCATTGCGCGCCGACAATGCCGATGAACGGCTGACGCCGCTTGCCGCGAAGCTGGGGA
TCGCCTCGGTGCAGCGGATGCAGCGCTATGGCGATGTCATGCAGCGGCTCGACGCGGCGCGCGAATTGGCCAGATCGGTG
GCGATGACCCCGAATGAGGCGGCGCGGCAAGGGCTGGAGATCAACCGGGACGGCGTGCGCCGGTCGGGTTATGAGCTGCT
GGCCTATCCCGACGTCGATGTCGCCTGGCTGGCCAGGGTCGAGCCAAAATTTGCGGCGATCGACGCCAAGACCGCGGAAC
GTCTCGAAACGGAAGCGAAATATTCGGTCTATCTCGACCGGCAGAAGAGCGATGTCGCGCAGATCCGCCACGAGGAGAGC
CGGCTGATCCCCGAGACGGTCGATTTCGCAGGTGTGCCGGGCCTGTCCAATGAATTGAAACAGAAGATGCAGGCGCGGCG
GCCGCGGTCCATCGCCGACGCGCAGCGCATGGAGGGCATGACGCCGGCGGCATTGGCGATCATTGTCGCGCATGTCCGGC
ATTATGAGAATGCGCAGAGAGACGTTGCGTGA

Upstream 100 bases:

>100_bases
TCACCCCTGTTTCACGTGAAACTTGCCGCGAAGTTTTCTTGACAGCTTGGCCCTGCGGGGACATGTGTCCCTCAATCGCT
TTTTGAGTCCAGGATTTGAA

Downstream 100 bases:

>100_bases
GCTCTTTCTCCCTAGAGAGCCTGCAGGACGCGGCGGGTCCGGTTTCACGTGAAACATTCGATCGCCTGGTGGCGTTCGAA
GCCATGTTCCAGAAATGGAA

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 623; Mature: 622

Protein sequence:

>623_residues
MTDHYDVVVVGGGHAGCEAASAAARAGAKTALVTLRFDTIGVMSCNPAIGGLGKGHLVREIDAMDGLMGRVADAAGIQFR
LLNRRKGPAVRGPRTQADRKLYRLAMQEAIRQQNDLDVVEGEVLDFEINEGRITAVLLAGGRRLACGAVVLTTGTFLRGL
IHIGEKKIVAGRMNEQASLGLSATMDRAGFKLGRLKTGTPPRLDGKTIDWASLESQAADEDPVPFSLMSDRITTPQIECG
ITRTTSATHELIRANLGRSAMYSGSIEGVGPRYCPSIEDKIVKFGDRDGHQIFLEPEGLDDDTVYPNGISTSLPQDVQLE
ILKTIPGLERATMLQPGYAIEYDHVDPRELHQTLETKRIAGLFLAGQINGTTGYEEAAGQGLLAGLNAARRAAGGEQIVL
SRTEAYIGVMVDDLTSRGISEPYRMFTSRAEFRLSLRADNADERLTPLAAKLGIASVQRMQRYGDVMQRLDAARELARSV
AMTPNEAARQGLEINRDGVRRSGYELLAYPDVDVAWLARVEPKFAAIDAKTAERLETEAKYSVYLDRQKSDVAQIRHEES
RLIPETVDFAGVPGLSNELKQKMQARRPRSIADAQRMEGMTPAALAIIVAHVRHYENAQRDVA

Sequences:

>Translated_623_residues
MTDHYDVVVVGGGHAGCEAASAAARAGAKTALVTLRFDTIGVMSCNPAIGGLGKGHLVREIDAMDGLMGRVADAAGIQFR
LLNRRKGPAVRGPRTQADRKLYRLAMQEAIRQQNDLDVVEGEVLDFEINEGRITAVLLAGGRRLACGAVVLTTGTFLRGL
IHIGEKKIVAGRMNEQASLGLSATMDRAGFKLGRLKTGTPPRLDGKTIDWASLESQAADEDPVPFSLMSDRITTPQIECG
ITRTTSATHELIRANLGRSAMYSGSIEGVGPRYCPSIEDKIVKFGDRDGHQIFLEPEGLDDDTVYPNGISTSLPQDVQLE
ILKTIPGLERATMLQPGYAIEYDHVDPRELHQTLETKRIAGLFLAGQINGTTGYEEAAGQGLLAGLNAARRAAGGEQIVL
SRTEAYIGVMVDDLTSRGISEPYRMFTSRAEFRLSLRADNADERLTPLAAKLGIASVQRMQRYGDVMQRLDAARELARSV
AMTPNEAARQGLEINRDGVRRSGYELLAYPDVDVAWLARVEPKFAAIDAKTAERLETEAKYSVYLDRQKSDVAQIRHEES
RLIPETVDFAGVPGLSNELKQKMQARRPRSIADAQRMEGMTPAALAIIVAHVRHYENAQRDVA
>Mature_622_residues
TDHYDVVVVGGGHAGCEAASAAARAGAKTALVTLRFDTIGVMSCNPAIGGLGKGHLVREIDAMDGLMGRVADAAGIQFRL
LNRRKGPAVRGPRTQADRKLYRLAMQEAIRQQNDLDVVEGEVLDFEINEGRITAVLLAGGRRLACGAVVLTTGTFLRGLI
HIGEKKIVAGRMNEQASLGLSATMDRAGFKLGRLKTGTPPRLDGKTIDWASLESQAADEDPVPFSLMSDRITTPQIECGI
TRTTSATHELIRANLGRSAMYSGSIEGVGPRYCPSIEDKIVKFGDRDGHQIFLEPEGLDDDTVYPNGISTSLPQDVQLEI
LKTIPGLERATMLQPGYAIEYDHVDPRELHQTLETKRIAGLFLAGQINGTTGYEEAAGQGLLAGLNAARRAAGGEQIVLS
RTEAYIGVMVDDLTSRGISEPYRMFTSRAEFRLSLRADNADERLTPLAAKLGIASVQRMQRYGDVMQRLDAARELARSVA
MTPNEAARQGLEINRDGVRRSGYELLAYPDVDVAWLARVEPKFAAIDAKTAERLETEAKYSVYLDRQKSDVAQIRHEESR
LIPETVDFAGVPGLSNELKQKMQARRPRSIADAQRMEGMTPAALAIIVAHVRHYENAQRDVA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=639, Percent_Identity=43.8184663536776, Blast_Score=514, Evalue=1e-145,
Organism=Homo sapiens, GI19882217, Length=664, Percent_Identity=42.1686746987952, Blast_Score=499, Evalue=1e-141,
Organism=Homo sapiens, GI183227703, Length=679, Percent_Identity=41.2371134020619, Blast_Score=494, Evalue=1e-140,
Organism=Escherichia coli, GI2367273, Length=619, Percent_Identity=49.7576736672052, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17534255, Length=618, Percent_Identity=42.8802588996764, Blast_Score=498, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6321202, Length=622, Percent_Identity=45.9807073954984, Blast_Score=554, Evalue=1e-158,
Organism=Drosophila melanogaster, GI24658174, Length=636, Percent_Identity=46.8553459119497, Blast_Score=545, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_RHILO (Q98DZ1)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105343.1
- ProteinModelPortal:   Q98DZ1
- SMR:   Q98DZ1
- GeneID:   1228004
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4482
- NMPDR:   fig|266835.1.peg.3447
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 67827; Mature: 67696

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: BINDING 123-123 BINDING 178-178 BINDING 367-367

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHYDVVVVGGGHAGCEAASAAARAGAKTALVTLRFDTIGVMSCNPAIGGLGKGHLVRE
CCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECEEEEEECCCCCCCCCCCHHHHH
IDAMDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYRLAMQEAIRQQNDLDVVE
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEC
GEVLDFEINEGRITAVLLAGGRRLACGAVVLTTGTFLRGLIHIGEKKIVAGRMNEQASLG
CEEEEEEECCCEEEEEEEECCCEEECCEEEEHHHHHHHHHHHHCCCEEEECCCCCHHHCC
LSATMDRAGFKLGRLKTGTPPRLDGKTIDWASLESQAADEDPVPFSLMSDRITTPQIECG
CHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCEEEC
ITRTTSATHELIRANLGRSAMYSGSIEGVGPRYCPSIEDKIVKFGDRDGHQIFLEPEGLD
CEECCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCC
DDTVYPNGISTSLPQDVQLEILKTIPGLERATMLQPGYAIEYDHVDPRELHQTLETKRIA
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHEECCCCEEEECCCCHHHHHHHHHHHHHH
GLFLAGQINGTTGYEEAAGQGLLAGLNAARRAAGGEQIVLSRTEAYIGVMVDDLTSRGIS
EEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEHEEHHHHHCCCC
EPYRMFTSRAEFRLSLRADNADERLTPLAAKLGIASVQRMQRYGDVMQRLDAARELARSV
HHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMTPNEAARQGLEINRDGVRRSGYELLAYPDVDVAWLARVEPKFAAIDAKTAERLETEAK
CCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHEECCCCCEEECHHHHHHHHHCCE
YSVYLDRQKSDVAQIRHEESRLIPETVDFAGVPGLSNELKQKMQARRPRSIADAQRMEGM
EEEEEECCHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCC
TPAALAIIVAHVRHYENAQRDVA
CHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDHYDVVVVGGGHAGCEAASAAARAGAKTALVTLRFDTIGVMSCNPAIGGLGKGHLVRE
CCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECEEEEEECCCCCCCCCCCHHHHH
IDAMDGLMGRVADAAGIQFRLLNRRKGPAVRGPRTQADRKLYRLAMQEAIRQQNDLDVVE
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEC
GEVLDFEINEGRITAVLLAGGRRLACGAVVLTTGTFLRGLIHIGEKKIVAGRMNEQASLG
CEEEEEEECCCEEEEEEEECCCEEECCEEEEHHHHHHHHHHHHCCCEEEECCCCCHHHCC
LSATMDRAGFKLGRLKTGTPPRLDGKTIDWASLESQAADEDPVPFSLMSDRITTPQIECG
CHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCEEEC
ITRTTSATHELIRANLGRSAMYSGSIEGVGPRYCPSIEDKIVKFGDRDGHQIFLEPEGLD
CEECCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCC
DDTVYPNGISTSLPQDVQLEILKTIPGLERATMLQPGYAIEYDHVDPRELHQTLETKRIA
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHEECCCCEEEECCCCHHHHHHHHHHHHHH
GLFLAGQINGTTGYEEAAGQGLLAGLNAARRAAGGEQIVLSRTEAYIGVMVDDLTSRGIS
EEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEHEEHHHHHCCCC
EPYRMFTSRAEFRLSLRADNADERLTPLAAKLGIASVQRMQRYGDVMQRLDAARELARSV
HHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMTPNEAARQGLEINRDGVRRSGYELLAYPDVDVAWLARVEPKFAAIDAKTAERLETEAK
CCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHEECCCCCEEECHHHHHHHHHCCE
YSVYLDRQKSDVAQIRHEESRLIPETVDFAGVPGLSNELKQKMQARRPRSIADAQRMEGM
EEEEEECCHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCC
TPAALAIIVAHVRHYENAQRDVA
CHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968