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The map label for this gene is tesA [C]

Identifier: 13473671

GI number: 13473671

Start: 3457593

End: 3458309

Strand: Direct

Name: tesA [C]

Synonym: mlr4347

Alternate gene names: 13473671

Gene position: 3457593-3458309 (Clockwise)

Preceding gene: 13473666

Following gene: 13473672

Centisome position: 49.14

GC content: 65.27

Gene sequence:

>717_bases
ATGGAACGTGAAGGCTCTGTTTGCCGGAAGCCGTCGCCCGGAAGAATCCTTTGGTCATATGGGGCCTGCCGCATGTCTTT
CAAACGCCAGATAGCCGCAGGCTTGATCCTTTTCCTCGCCCTTTGCGGCGCCATTTCGTCGGCGCGGGCCGAACCCTTCA
AGATCGTCGGCTTCGGCGACAGCCTGACGGCGGGATACGGTCTCGGGCCCGGCGAGGGTTTTACCGACAAGCTCCAGGCC
GCACTTCGGGCCAAAGGCCGTGATGTCACCGTCGCCAATGCCGGTGTTTCCGGCGACACCACCAGCGGCGGCCTGGCGCG
GCTCGACTGGTCGGTGCCGGACGGAACCCGGCTGGTCATCCTCGAACTCGGCGCCAACGACATGCTGCGCGGCGTTTTGC
CCGATATCGCCAGGAAGAACCTCGACGAGATGCTGGCCAGGCTCAAGCAGCGCAAGATCGCCGTGCTTCTGGCCGGCATG
CGCGCCGCGCCCAATCTCGGCGCCGATTACCAGACCGCCTTCGACGCCATCTTCCCGGAGCTGGCGAAGAAATACGATGT
CGCACTCTACCCGTTCTTCCTCGATGGCGTCGCCGGCCAGCCCGGCATGCAGCTCGAGGATGGCCTGCATCCGAGCGCCA
AAGGGGTCGACCTGATGGTCGAGCGCATCCTGCCGACGGTCGAGAAGGCCATTGCGGCGGTGCCCGGAGGCGCGTGA

Upstream 100 bases:

>100_bases
GACGCCCTTCAGCACGTGGACCGACGAAGCGCCCTCGCCCAGCGTCAGGGATACGTCTTTCAGCGCGATGACGGCTTCTG
TCATAATGAAAGTGTCCTAT

Downstream 100 bases:

>100_bases
GGCCGGCCGGAACCGCTTTCCGTTAGGGAAATTTTTAGCAAAGACTGTGACCAATAAACCTCTTGCTCCGTTCGACTATC
GATGATTCGCTATAGGTGAC

Product: acyl-CoA thioesterase

Products: NA

Alternate protein names: Aryl-ester hydrolase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEREGSVCRKPSPGRILWSYGACRMSFKRQIAAGLILFLALCGAISSARAEPFKIVGFGDSLTAGYGLGPGEGFTDKLQA
ALRAKGRDVTVANAGVSGDTTSGGLARLDWSVPDGTRLVILELGANDMLRGVLPDIARKNLDEMLARLKQRKIAVLLAGM
RAAPNLGADYQTAFDAIFPELAKKYDVALYPFFLDGVAGQPGMQLEDGLHPSAKGVDLMVERILPTVEKAIAAVPGGA

Sequences:

>Translated_238_residues
MEREGSVCRKPSPGRILWSYGACRMSFKRQIAAGLILFLALCGAISSARAEPFKIVGFGDSLTAGYGLGPGEGFTDKLQA
ALRAKGRDVTVANAGVSGDTTSGGLARLDWSVPDGTRLVILELGANDMLRGVLPDIARKNLDEMLARLKQRKIAVLLAGM
RAAPNLGADYQTAFDAIFPELAKKYDVALYPFFLDGVAGQPGMQLEDGLHPSAKGVDLMVERILPTVEKAIAAVPGGA
>Mature_238_residues
MEREGSVCRKPSPGRILWSYGACRMSFKRQIAAGLILFLALCGAISSARAEPFKIVGFGDSLTAGYGLGPGEGFTDKLQA
ALRAKGRDVTVANAGVSGDTTSGGLARLDWSVPDGTRLVILELGANDMLRGVLPDIARKNLDEMLARLKQRKIAVLLAGM
RAAPNLGADYQTAFDAIFPELAKKYDVALYPFFLDGVAGQPGMQLEDGLHPSAKGVDLMVERILPTVEKAIAAVPGGA

Specific function: Favors the hydrolysis of several arylesters [H]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786702, Length=211, Percent_Identity=35.5450236966825, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =3.1.1.2 [H]

Molecular weight: Translated: 25148; Mature: 25148

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEREGSVCRKPSPGRILWSYGACRMSFKRQIAAGLILFLALCGAISSARAEPFKIVGFGD
CCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
SLTAGYGLGPGEGFTDKLQAALRAKGRDVTVANAGVSGDTTSGGLARLDWSVPDGTRLVI
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEEE
LELGANDMLRGVLPDIARKNLDEMLARLKQRKIAVLLAGMRAAPNLGADYQTAFDAIFPE
EEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LAKKYDVALYPFFLDGVAGQPGMQLEDGLHPSAKGVDLMVERILPTVEKAIAAVPGGA
HHHHHCCEEEHHHHCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEREGSVCRKPSPGRILWSYGACRMSFKRQIAAGLILFLALCGAISSARAEPFKIVGFGD
CCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
SLTAGYGLGPGEGFTDKLQAALRAKGRDVTVANAGVSGDTTSGGLARLDWSVPDGTRLVI
CCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEEE
LELGANDMLRGVLPDIARKNLDEMLARLKQRKIAVLLAGMRAAPNLGADYQTAFDAIFPE
EEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LAKKYDVALYPFFLDGVAGQPGMQLEDGLHPSAKGVDLMVERILPTVEKAIAAVPGGA
HHHHHCCEEEHHHHCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8141782 [H]