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The map label for this gene is cynT [H]

Identifier: 13473511

GI number: 13473511

Start: 3306445

End: 3307089

Strand: Direct

Name: cynT [H]

Synonym: mlr4135

Alternate gene names: 13473511

Gene position: 3306445-3307089 (Clockwise)

Preceding gene: 13473510

Following gene: 13473512

Centisome position: 46.99

GC content: 64.34

Gene sequence:

>645_bases
ATGCCTCATCTTCCCGATCACCTCCTCGCCGGCTATCGCAATTTTATGAACGGCCGCTATCTCACGGAGAGCGGCCGCTA
TCGCGAGCTCGCCCGCGAGGGGCAGGCCCCTGAGACGATGATAGTCGCCTGTTGCGACTCCCGCGCGGCCCCCGAAGCGA
TCTTCGACGCCGGGCCGGGCGAACTGTTCGTGCTGCGCAATGTCGGCAATCTGGTGCCGCCCTACGAGCCGGACGGCGAG
TTCCATTCGACCTCGGCGGCGCTCGAATTCGCGGTGCAGAGCCTCAAGGTCAAGAACATCGTTGTCATGGGCCATGGCCG
CTGCGGCGGCATCCGCGCCGCGCTCGACCCCAATGCCGCGCCGCTGTCTCCCGGCGACTTCATCGGCAAATGGATGAGCC
TGATCGCGCCTGCCGCCGAAACCGTCTCCTCCAGCACCTTCATGACGGCGGCGGAGCGCCAGACGGCGCTTGAACGCATC
TCGATCCGCTATTCCATCGCCAACCTCAGGACCTTTCCCTGTGTCTCGATTCTCGAGGGCAAGGGGCGGTTGTCGCTGCA
CGGAGCCTGGTTCGACATTTCGACCGGTGAGCTCTGGGTGATGAACAAGGAGACCGGCGATTTCGAGCGACCGGTGCTGG
AATGA

Upstream 100 bases:

>100_bases
CCCCACAATTCTGCATTGCTCGCAACGGGCTTTTGCCGTTAGAGCCTTTCTCGACCGCAACGAGCTGCCGCCTCCAACCC
CGGAAAGGCCTTAGCCGCCC

Downstream 100 bases:

>100_bases
ACGGCACGGCGCGCCCGGTGAGGAACGTCCGGTCGGCCGTTTTCACCGCCGCCGCATTGCTGATAGCGATCGTTGCCGCG
CGCGCCGATGACGGCGCCAT

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MPHLPDHLLAGYRNFMNGRYLTESGRYRELAREGQAPETMIVACCDSRAAPEAIFDAGPGELFVLRNVGNLVPPYEPDGE
FHSTSAALEFAVQSLKVKNIVVMGHGRCGGIRAALDPNAAPLSPGDFIGKWMSLIAPAAETVSSSTFMTAAERQTALERI
SIRYSIANLRTFPCVSILEGKGRLSLHGAWFDISTGELWVMNKETGDFERPVLE

Sequences:

>Translated_214_residues
MPHLPDHLLAGYRNFMNGRYLTESGRYRELAREGQAPETMIVACCDSRAAPEAIFDAGPGELFVLRNVGNLVPPYEPDGE
FHSTSAALEFAVQSLKVKNIVVMGHGRCGGIRAALDPNAAPLSPGDFIGKWMSLIAPAAETVSSSTFMTAAERQTALERI
SIRYSIANLRTFPCVSILEGKGRLSLHGAWFDISTGELWVMNKETGDFERPVLE
>Mature_213_residues
PHLPDHLLAGYRNFMNGRYLTESGRYRELAREGQAPETMIVACCDSRAAPEAIFDAGPGELFVLRNVGNLVPPYEPDGEF
HSTSAALEFAVQSLKVKNIVVMGHGRCGGIRAALDPNAAPLSPGDFIGKWMSLIAPAAETVSSSTFMTAAERQTALERIS
IRYSIANLRTFPCVSILEGKGRLSLHGAWFDISTGELWVMNKETGDFERPVLE

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=201, Percent_Identity=30.8457711442786, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786318, Length=176, Percent_Identity=28.9772727272727, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25147564, Length=235, Percent_Identity=25.1063829787234, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115532990, Length=213, Percent_Identity=26.2910798122066, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=177, Percent_Identity=26.5536723163842, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23371; Mature: 23240

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHLPDHLLAGYRNFMNGRYLTESGRYRELAREGQAPETMIVACCDSRAAPEAIFDAGPG
CCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCCCC
ELFVLRNVGNLVPPYEPDGEFHSTSAALEFAVQSLKVKNIVVMGHGRCGGIRAALDPNAA
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCCC
PLSPGDFIGKWMSLIAPAAETVSSSTFMTAAERQTALERISIRYSIANLRTFPCVSILEG
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEECC
KGRLSLHGAWFDISTGELWVMNKETGDFERPVLE
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
PHLPDHLLAGYRNFMNGRYLTESGRYRELAREGQAPETMIVACCDSRAAPEAIFDAGPG
CCCHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHCCCCC
ELFVLRNVGNLVPPYEPDGEFHSTSAALEFAVQSLKVKNIVVMGHGRCGGIRAALDPNAA
CEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEECCCCC
PLSPGDFIGKWMSLIAPAAETVSSSTFMTAAERQTALERISIRYSIANLRTFPCVSILEG
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEECC
KGRLSLHGAWFDISTGELWVMNKETGDFERPVLE
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]