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The map label for this gene is pdxY [H]

Identifier: 13473509

GI number: 13473509

Start: 3304625

End: 3305509

Strand: Direct

Name: pdxY [H]

Synonym: mlr4132

Alternate gene names: 13473509

Gene position: 3304625-3305509 (Clockwise)

Preceding gene: 13473508

Following gene: 13473510

Centisome position: 46.97

GC content: 69.38

Gene sequence:

>885_bases
ATGAGCGCCGAAAAACCCGACGCGCCGCGTGCGGTCATCGTCATCTCCAGCCATGTCGCCCGTGGCTCGGTCGGCAACCG
TGCCGCCGTCTTTGCCTTGGAGACCCTGGGCTTTCCGGTCTGGGCCGTGCCGACGGTCATCCTGCCCTGGCATCCCGGCC
ATGGGCGGGCGACGCGCATCGTGCCGCCGCTCGACCAGTTCAAGGCTTTTATGGCCGATCTCGAGCGCGCGCCATGGCTG
GGCGAGGTCGGCGCGGTTCTGTCGGGCTATCTCGGCGAGGCCGGCCAGGCCGAGGCCGTCGCCTCGCTGGTCGCCGCGGT
CAAGGCCAGGACGCCTGATGCGGTCTATATCTGCGATCCGGTGATGGGCGATTCCGGCGGCCTCTATGTGCCGGAGGCCA
CCGCCGCCGCCATGCGCGACCGCCTGGTGCCGATCGCCGACATCGCCACGCCCAACCGCTACGAACTGGAATGGATGGCC
GGCGCGCCGCTGCCCGATCTGAAATCGGTGATCGCGGCAGCACTCCACGCCGGGCCGTCGACGATGCTGGTCACCTCGGC
GCAGTCGATGATGATTGGCGGCACCGGCAATCTGCTGCTCGACGGCACCCAGGCGCTGCTCGCCGAGCACCGCGTGATCG
ACAAGCCGCCGAACGGCCTGGGTGACCTGACGGCGGCTGTCTACCTCGCCCGCATCCTTTCCGGCCAGCCGCCGATCAAG
GCGCTGCAATCGACCACGGCGGCGGTTTACGAGATCCTGGCGCGTACGGCAAAACGCGGCGGCGACGAGCTGCAGCTCGA
AACCGATGCGCAGAGCCTGTCGCACCCGATGGCCATGGTGCAGTTGCGCCACCTCACGCATCCGGGGCGGGACCGCCGGG
CGTGA

Upstream 100 bases:

>100_bases
GGCACGCGCATTGGCAGGATACTCGGCCTGCTTCTGGCGCTGGGCCTGATGGTCTGGCTCGTGCTTTTCCTCACCCGGGG
CAGCTAGGAATCAAAAAACA

Downstream 100 bases:

>100_bases
CCTCGGCCGGGGTGGTGCTCGTCGGCGCCGATGGCTGCAAGGCCGGCTGGATCGCCGTGCGGCGCGAACTCGGTTCCACA
CCTCGTAGCCCCGGTTCAGC

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSAEKPDAPRAVIVISSHVARGSVGNRAAVFALETLGFPVWAVPTVILPWHPGHGRATRIVPPLDQFKAFMADLERAPWL
GEVGAVLSGYLGEAGQAEAVASLVAAVKARTPDAVYICDPVMGDSGGLYVPEATAAAMRDRLVPIADIATPNRYELEWMA
GAPLPDLKSVIAAALHAGPSTMLVTSAQSMMIGGTGNLLLDGTQALLAEHRVIDKPPNGLGDLTAAVYLARILSGQPPIK
ALQSTTAAVYEILARTAKRGGDELQLETDAQSLSHPMAMVQLRHLTHPGRDRRA

Sequences:

>Translated_294_residues
MSAEKPDAPRAVIVISSHVARGSVGNRAAVFALETLGFPVWAVPTVILPWHPGHGRATRIVPPLDQFKAFMADLERAPWL
GEVGAVLSGYLGEAGQAEAVASLVAAVKARTPDAVYICDPVMGDSGGLYVPEATAAAMRDRLVPIADIATPNRYELEWMA
GAPLPDLKSVIAAALHAGPSTMLVTSAQSMMIGGTGNLLLDGTQALLAEHRVIDKPPNGLGDLTAAVYLARILSGQPPIK
ALQSTTAAVYEILARTAKRGGDELQLETDAQSLSHPMAMVQLRHLTHPGRDRRA
>Mature_293_residues
SAEKPDAPRAVIVISSHVARGSVGNRAAVFALETLGFPVWAVPTVILPWHPGHGRATRIVPPLDQFKAFMADLERAPWLG
EVGAVLSGYLGEAGQAEAVASLVAAVKARTPDAVYICDPVMGDSGGLYVPEATAAAMRDRLVPIADIATPNRYELEWMAG
APLPDLKSVIAAALHAGPSTMLVTSAQSMMIGGTGNLLLDGTQALLAEHRVIDKPPNGLGDLTAAVYLARILSGQPPIKA
LQSTTAAVYEILARTAKRGGDELQLETDAQSLSHPMAMVQLRHLTHPGRDRRA

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=267, Percent_Identity=32.5842696629214, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1787924, Length=280, Percent_Identity=32.5, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788758, Length=265, Percent_Identity=31.6981132075472, Blast_Score=113, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17507759, Length=185, Percent_Identity=32.4324324324324, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17507757, Length=189, Percent_Identity=31.7460317460317, Blast_Score=104, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6320806, Length=272, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324354, Length=163, Percent_Identity=32.5153374233129, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45553007, Length=303, Percent_Identity=28.0528052805281, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 30962; Mature: 30831

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEKPDAPRAVIVISSHVARGSVGNRAAVFALETLGFPVWAVPTVILPWHPGHGRATRI
CCCCCCCCCEEEEEEECCHHCCCCCCCHHEEEHHHHCCCHHHCCEEEEECCCCCCCCEEC
VPPLDQFKAFMADLERAPWLGEVGAVLSGYLGEAGQAEAVASLVAAVKARTPDAVYICDP
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECC
VMGDSGGLYVPEATAAAMRDRLVPIADIATPNRYELEWMAGAPLPDLKSVIAAALHAGPS
CCCCCCCEECCCHHHHHHHHCCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
TMLVTSAQSMMIGGTGNLLLDGTQALLAEHRVIDKPPNGLGDLTAAVYLARILSGQPPIK
EEEEECCCCEEECCCCCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
ALQSTTAAVYEILARTAKRGGDELQLETDAQSLSHPMAMVQLRHLTHPGRDRRA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAEKPDAPRAVIVISSHVARGSVGNRAAVFALETLGFPVWAVPTVILPWHPGHGRATRI
CCCCCCCCEEEEEEECCHHCCCCCCCHHEEEHHHHCCCHHHCCEEEEECCCCCCCCEEC
VPPLDQFKAFMADLERAPWLGEVGAVLSGYLGEAGQAEAVASLVAAVKARTPDAVYICDP
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEECC
VMGDSGGLYVPEATAAAMRDRLVPIADIATPNRYELEWMAGAPLPDLKSVIAAALHAGPS
CCCCCCCEECCCHHHHHHHHCCCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
TMLVTSAQSMMIGGTGNLLLDGTQALLAEHRVIDKPPNGLGDLTAAVYLARILSGQPPIK
EEEEECCCCEEECCCCCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
ALQSTTAAVYEILARTAKRGGDELQLETDAQSLSHPMAMVQLRHLTHPGRDRRA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]