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The map label for this gene is ppa

Identifier: 13473502

GI number: 13473502

Start: 3299670

End: 3300203

Strand: Reverse

Name: ppa

Synonym: mll4120

Alternate gene names: 13473502

Gene position: 3300203-3299670 (Counterclockwise)

Preceding gene: 13473503

Following gene: 13473499

Centisome position: 46.9

GC content: 60.86

Gene sequence:

>534_bases
ATGCGCATCGAAGCCATTGCCACCGGAAAGAATCCACCTGAAGACGTCAACGTCATCATCGAAGTGCCGATCGGCGGCGA
GCCGATCAAGTATGAGATGGACAAGGAGGCCGGCACGCTGTTCGTCGACCGCTTCCTGCACACCTCGATGCGCTACCCCG
GCAATTACGGCTTCGTGCCGCACACGCTGTCGGGCGACGGCGATCCGATCGACGTGCTGGTCTGCAACACGCGCGCGCTG
GTCCCGGGCTGCGTCATCAATGTCAGGCCGATCGGCGTGCTGGTGATGGAGGATAATGCCGGCCAGGACGAGAAGGTCAT
CGCCGTGCCGTCGCCCAAGCTGACGCTGCGCTACGAGAACGTCACCGAATACACGCATCTGCCCGAGATCACGCGCCAGC
AGGTGCAGCACTTCTTCGAGCACTACAAGGATCTCGAGCCCGGCAAATGGGTCAAGATCGAGGGCTGGCACGATTCCAAA
TATGCCAAGAAGATGATCGTCGACGCGATCGAGCGGGCGAAGAAGGGCAAGTAG

Upstream 100 bases:

>100_bases
CGCCATCGCGTCTCAGCTGATGTCCGCGAACACGATTCGCCGCATTGCGCCATTCTGCGCCGCCCGCTATCTCCTCCCCA
ACCGAGAGAGGGACAAAGCC

Downstream 100 bases:

>100_bases
TCCGAGCGGTCAGTTATCCACCCGGCCGAAAGCCGGCACATTGCCGATGACGGTGTGCCGGTCCTTGCCGCAGGCGAAGG
TACGGGCCTTCTCGTCGGCG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRIEAIATGKNPPEDVNVIIEVPIGGEPIKYEMDKEAGTLFVDRFLHTSMRYPGNYGFVPHTLSGDGDPIDVLVCNTRAL
VPGCVINVRPIGVLVMEDNAGQDEKVIAVPSPKLTLRYENVTEYTHLPEITRQQVQHFFEHYKDLEPGKWVKIEGWHDSK
YAKKMIVDAIERAKKGK

Sequences:

>Translated_177_residues
MRIEAIATGKNPPEDVNVIIEVPIGGEPIKYEMDKEAGTLFVDRFLHTSMRYPGNYGFVPHTLSGDGDPIDVLVCNTRAL
VPGCVINVRPIGVLVMEDNAGQDEKVIAVPSPKLTLRYENVTEYTHLPEITRQQVQHFFEHYKDLEPGKWVKIEGWHDSK
YAKKMIVDAIERAKKGK
>Mature_177_residues
MRIEAIATGKNPPEDVNVIIEVPIGGEPIKYEMDKEAGTLFVDRFLHTSMRYPGNYGFVPHTLSGDGDPIDVLVCNTRAL
VPGCVINVRPIGVLVMEDNAGQDEKVIAVPSPKLTLRYENVTEYTHLPEITRQQVQHFFEHYKDLEPGKWVKIEGWHDSK
YAKKMIVDAIERAKKGK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=174, Percent_Identity=55.1724137931034, Blast_Score=209, Evalue=9e-56,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR_RHILO (Q98ER2)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105069.1
- ProteinModelPortal:   Q98ER2
- SMR:   Q98ER2
- GeneID:   1227730
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4120
- NMPDR:   fig|266835.1.peg.3173
- HOGENOM:   HBG529150
- OMA:   PVALMKM
- ProtClustDB:   PRK01250
- BRENDA:   3.6.1.1
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 19971; Mature: 19971

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEAIATGKNPPEDVNVIIEVPIGGEPIKYEMDKEAGTLFVDRFLHTSMRYPGNYGFVP
CEEEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC
HTLSGDGDPIDVLVCNTRALVPGCVINVRPIGVLVMEDNAGQDEKVIAVPSPKLTLRYEN
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEEECCCCEEEEECC
VTEYTHLPEITRQQVQHFFEHYKDLEPGKWVKIEGWHDSKYAKKMIVDAIERAKKGK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIEAIATGKNPPEDVNVIIEVPIGGEPIKYEMDKEAGTLFVDRFLHTSMRYPGNYGFVP
CEEEEEECCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC
HTLSGDGDPIDVLVCNTRALVPGCVINVRPIGVLVMEDNAGQDEKVIAVPSPKLTLRYEN
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEEECCCCEEEEECC
VTEYTHLPEITRQQVQHFFEHYKDLEPGKWVKIEGWHDSKYAKKMIVDAIERAKKGK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968