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The map label for this gene is tlpA [H]

Identifier: 13473026

GI number: 13473026

Start: 2829156

End: 2829782

Strand: Reverse

Name: tlpA [H]

Synonym: mll3505

Alternate gene names: 13473026

Gene position: 2829782-2829156 (Counterclockwise)

Preceding gene: 13473030

Following gene: 13473024

Centisome position: 40.22

GC content: 66.35

Gene sequence:

>627_bases
GTGGCGGGAGCGCTGGCCGGCGCGGTCGCGGTATATGTCAGCGAGAGCCGGTCTGGCAACAATGCACCGGCCCGGGTGGC
GGTCGGCGGCAGCAAGGACGACGTCGCCTGCGCCGCCAAGAGCGGCCGCGCCAAGAAGATCGCGGCTGCCGCCACCGGCG
AGGTTGCGGCCCTGTTGCCCGCCGATCCGCCGCAGTCGATGAAAAGCCTTGCCTTCAATGGCCCGGACGGCAAGCCGATG
ACGATCGCCGACCATGCCGGCAAGACGGTGCTGCTCAATCTCTGGGCGACATGGTGCGCACCGTGCCGCGCTGAAATGCC
GGCGCTCAATGCGCTGCAGAAGGACAAGGGCAGCGACGCCTTTCAGGTCATCGCCGTCAATGTCGACGCCGGCGACGATG
TGAAGCCGAAGAAATTTCTCAAGGAGACAGGCGTCGAGGCGCTCGGCTATTTCAGGGATTCGACGGTGGCGCTGTTCAAC
GACCTCAAGGCGCGTGGCCTTGCGCTCGGCCTTCCCGTCACCATGCTGATCGACAGCGAAGGCTGTCTGATCGCGCATAT
GAACGGCCCGGCTGAATGGTCGGGGCGCGACGCCAGGCGGCTGGTCGAGACGGCACTCGGATCGTGA

Upstream 100 bases:

>100_bases
TGTCGCTCATCGCTATAAACCCGTGCTTCGGAGCAGTTTTGAGAAAATGGCAGACGGAAACAGATTTTTCCCGGCCCCGC
GCCTGATCCTCGCCGCTTTG

Downstream 100 bases:

>100_bases
GGGATCAGGCCGAGCGCACGCTTGGCTTCAGCAATACGACGCTGCCCTCTCGATGGTCGGCGCGGGCTGGGGTGCGCTTG
CCGTGGCCGGTCAGGTCGTC

Product: thioredoxin-like protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MAGALAGAVAVYVSESRSGNNAPARVAVGGSKDDVACAAKSGRAKKIAAAATGEVAALLPADPPQSMKSLAFNGPDGKPM
TIADHAGKTVLLNLWATWCAPCRAEMPALNALQKDKGSDAFQVIAVNVDAGDDVKPKKFLKETGVEALGYFRDSTVALFN
DLKARGLALGLPVTMLIDSEGCLIAHMNGPAEWSGRDARRLVETALGS

Sequences:

>Translated_208_residues
MAGALAGAVAVYVSESRSGNNAPARVAVGGSKDDVACAAKSGRAKKIAAAATGEVAALLPADPPQSMKSLAFNGPDGKPM
TIADHAGKTVLLNLWATWCAPCRAEMPALNALQKDKGSDAFQVIAVNVDAGDDVKPKKFLKETGVEALGYFRDSTVALFN
DLKARGLALGLPVTMLIDSEGCLIAHMNGPAEWSGRDARRLVETALGS
>Mature_207_residues
AGALAGAVAVYVSESRSGNNAPARVAVGGSKDDVACAAKSGRAKKIAAAATGEVAALLPADPPQSMKSLAFNGPDGKPMT
IADHAGKTVLLNLWATWCAPCRAEMPALNALQKDKGSDAFQVIAVNVDAGDDVKPKKFLKETGVEALGYFRDSTVALFND
LKARGLALGLPVTMLIDSEGCLIAHMNGPAEWSGRDARRLVETALGS

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21434; Mature: 21303

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGALAGAVAVYVSESRSGNNAPARVAVGGSKDDVACAAKSGRAKKIAAAATGEVAALLP
CCCHHHHEEEEEEECCCCCCCCCEEEEECCCCCCEEEECCCCCCEEEEEECCCCEEEEEC
ADPPQSMKSLAFNGPDGKPMTIADHAGKTVLLNLWATWCAPCRAEMPALNALQKDKGSDA
CCCHHHHHHHCCCCCCCCEEEEECCCCCEEEEEHHHHHHCCCCCCCCHHHHHHHCCCCCE
FQVIAVNVDAGDDVKPKKFLKETGVEALGYFRDSTVALFNDLKARGLALGLPVTMLIDSE
EEEEEEEECCCCCCCHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCEEECCCEEEEECCC
GCLIAHMNGPAEWSGRDARRLVETALGS
CEEEEECCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AGALAGAVAVYVSESRSGNNAPARVAVGGSKDDVACAAKSGRAKKIAAAATGEVAALLP
CCHHHHEEEEEEECCCCCCCCCEEEEECCCCCCEEEECCCCCCEEEEEECCCCEEEEEC
ADPPQSMKSLAFNGPDGKPMTIADHAGKTVLLNLWATWCAPCRAEMPALNALQKDKGSDA
CCCHHHHHHHCCCCCCCCEEEEECCCCCEEEEEHHHHHHCCCCCCCCHHHHHHHCCCCCE
FQVIAVNVDAGDDVKPKKFLKETGVEALGYFRDSTVALFNDLKARGLALGLPVTMLIDSE
EEEEEEEECCCCCCCHHHHHHHCCHHHHHHHCCCHHHHHHHHHHCCEEECCCEEEEECCC
GCLIAHMNGPAEWSGRDARRLVETALGS
CEEEEECCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]