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The map label for this gene is yfjP [H]

Identifier: 13473004

GI number: 13473004

Start: 2805264

End: 2805959

Strand: Reverse

Name: yfjP [H]

Synonym: mll3478

Alternate gene names: 13473004

Gene position: 2805959-2805264 (Counterclockwise)

Preceding gene: 13473007

Following gene: 13473003

Centisome position: 39.88

GC content: 66.67

Gene sequence:

>696_bases
GTGCTGCGGTTTTGGCGGTTGCTACTTTGCTGCACATTGGCGGGCAAGGCTACCATGCAACGAATCGCGACACTGGACGA
CATTGCCCGCGGGCTCGATGCGCTTTGCACCATCGACCCGCGCCTGGAAAAGGTGCGCGGCATGGCCGGCGAGGTGCCGC
TCAGGCTTTCGGAGCCGGGCTTCAGGAGCCTGGCCTCGATCATCGTCTCGCAGCAAGTGTCGCGGGCCAGCGCCGACGCC
ATCTTCGGCCGGCTGACGAAGCTCGTCGATCCGCTGACGCCGCAGGCGATCCTGGCCGCGGGCGAGGACATGTTTCGCGA
GGCCGGCCTGTCGCGGCCCAAGCAGCGCGGGCTGATCGCGGTCGCCCAGGCCGTGGCCGACGGGCTTGACCTCAATCACC
TCTGTTCGCTCGACGCTCAGGAGGCGATTACAACGATGACGGCCGTGCCCGGCATCGGTCCATGGACGGCGGAAGTGTAC
CTTCTGTTCGCCGCCGGGCACCCCGACATTTTCCCCGCGCGCGACGTTGCGCTGCAGAGCGCGGTCGGTCATGCGCTCGG
TATCGACCCGCGTCCGCCGGAGAAAACACTGATCGCTTTGGCCGAATCATGGAGCCCGTGGCGAGGTGTCGCATCGCGGC
TTTTCTGGTCCTATTATCGCGAAACCAGAGGGCGGGACGCCGCGCCACCGTCCTGA

Upstream 100 bases:

>100_bases
TGAGCAGCGCCGAATAGGCGTGGCCGAGATGCAGTTCGCCGTTGGGGCTGGGGGCGAAGCGGAATGTCAGGAGCGTCATG
TCTCGAGCGGCAATCGGGTT

Downstream 100 bases:

>100_bases
ATCCGCAAAAATGCATAAAAATCGGGGTTTTTTGACGGTTTGGGCAAGCGACAATCCGCTTCACATCCCTGTCATGTCGG
GCTTACAGTATCCGCGCCGT

Product: DNA-3-methyladenine glycosidase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLRFWRLLLCCTLAGKATMQRIATLDDIARGLDALCTIDPRLEKVRGMAGEVPLRLSEPGFRSLASIIVSQQVSRASADA
IFGRLTKLVDPLTPQAILAAGEDMFREAGLSRPKQRGLIAVAQAVADGLDLNHLCSLDAQEAITTMTAVPGIGPWTAEVY
LLFAAGHPDIFPARDVALQSAVGHALGIDPRPPEKTLIALAESWSPWRGVASRLFWSYYRETRGRDAAPPS

Sequences:

>Translated_231_residues
MLRFWRLLLCCTLAGKATMQRIATLDDIARGLDALCTIDPRLEKVRGMAGEVPLRLSEPGFRSLASIIVSQQVSRASADA
IFGRLTKLVDPLTPQAILAAGEDMFREAGLSRPKQRGLIAVAQAVADGLDLNHLCSLDAQEAITTMTAVPGIGPWTAEVY
LLFAAGHPDIFPARDVALQSAVGHALGIDPRPPEKTLIALAESWSPWRGVASRLFWSYYRETRGRDAAPPS
>Mature_231_residues
MLRFWRLLLCCTLAGKATMQRIATLDDIARGLDALCTIDPRLEKVRGMAGEVPLRLSEPGFRSLASIIVSQQVSRASADA
IFGRLTKLVDPLTPQAILAAGEDMFREAGLSRPKQRGLIAVAQAVADGLDLNHLCSLDAQEAITTMTAVPGIGPWTAEVY
LLFAAGHPDIFPARDVALQSAVGHALGIDPRPPEKTLIALAESWSPWRGVASRLFWSYYRETRGRDAAPPS

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 24999; Mature: 24999

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFWRLLLCCTLAGKATMQRIATLDDIARGLDALCTIDPRLEKVRGMAGEVPLRLSEPG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEECCCC
FRSLASIIVSQQVSRASADAIFGRLTKLVDPLTPQAILAAGEDMFREAGLSRPKQRGLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
VAQAVADGLDLNHLCSLDAQEAITTMTAVPGIGPWTAEVYLLFAAGHPDIFPARDVALQS
HHHHHHCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
AVGHALGIDPRPPEKTLIALAESWSPWRGVASRLFWSYYRETRGRDAAPPS
HHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLRFWRLLLCCTLAGKATMQRIATLDDIARGLDALCTIDPRLEKVRGMAGEVPLRLSEPG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCEEECCCC
FRSLASIIVSQQVSRASADAIFGRLTKLVDPLTPQAILAAGEDMFREAGLSRPKQRGLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
VAQAVADGLDLNHLCSLDAQEAITTMTAVPGIGPWTAEVYLLFAAGHPDIFPARDVALQS
HHHHHHCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
AVGHALGIDPRPPEKTLIALAESWSPWRGVASRLFWSYYRETRGRDAAPPS
HHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]