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The map label for this gene is dgoD1 [H]

Identifier: 13472342

GI number: 13472342

Start: 2107172

End: 2108386

Strand: Direct

Name: dgoD1 [H]

Synonym: mlr2605

Alternate gene names: 13472342

Gene position: 2107172-2108386 (Clockwise)

Preceding gene: 13472341

Following gene: 13472343

Centisome position: 29.95

GC content: 63.62

Gene sequence:

>1215_bases
ATGAAGATCACCGACGTCAAGACCTGGGTTGTCGGCAACCCGCCGCCCGGCATCGGCGGCAAGTATTTCATCTTCGTCAA
ACTGACCACCGACGGCGGCGTGGTCGGTTATGGCGAAGCCTACAACGCTACCTTCTCCGCCCATGTCACGGCGAAAATGG
TCGAGGACATGGCCGAGCGCTATCTCGTCGGCCGCGACCCGCACGACATCGAGAACTTCTTCCGCCGCGCCTATTCCTCC
GGCTTCACCCAGCGTCCCGATGTTTCCGGCATGGGCTGCTTCTCGGCACTGGAAATGGCCTGCTGGGACATCATCGGCAA
GGAGGCCAACAAGCCGGTCTACAAACTGCTCGGCGGCCAGGTGCACGAGACGCTGCGCTCCTACACCTACCTCTATCCGC
ACACGGGCAGCGTCCATTCGGAGGACGCGCCGGACGGCAGGAATGTCTACAACGACCCAGAACTGGCGGCGGCCTGCGCG
CTCGAATATGTCGAGCAGGGGTTCAATGCCGTCAAGCTCGACCCGGCCGGTCCCTATACCGCCTTCGACGGCCATCAGCC
GCGCCTGCTCGACATCGATGTCTCCACCCGGATGATCAAGGCGATCCGCGAGGCGGTCGGCACCCGCGCCGACATATTGT
TCGGCACGCACGGCCAGTTCACCGCGTCGGGCGCGCTGCGCATGGCCCGCGCCATCGAGCCCTATGATCCCTTGTGGTTC
GAGGAGCCGGTACCGCCCGACATGCCGGAGGTGATGGCGCAGGTCGCCCGCGGTACCTCCATCCCGATCGCCACCGGCGA
ACGGCTGACGACCAAGTTCGAATTCGCCCGCGTCATCGAAAACCGTGCCGCGACCATATTGCAGCCGGATCTCGGCCGCT
CTGGCGGCATCCTCGAAACCAAAAAGATCGCGGCCATGGCCGAGGCCTATCACATCCAGGTCGCGCCGCATTGCTATTGC
GGCCCGATCGTCGGCGCCGCCAACATCCAGCTGGCGGTGACGCTGCCCAACTTCCTCATCCTGGAATCGCTGAAGCAGTG
GGACGGCTTCCACGCCACGCTCTTGAAGAAGAAGATCGAATGGCAGGACGGCAACGTCATCCCGTCGAAGGAACCGGGGC
TGGGCGTCGAGCTCAACGAAGCGGTCTGCGATGCCCATCCCTACACCGGCAAGGATTTGCACCTGCAGATGATGCAGACC
CCGTTGATGCCGTGA

Upstream 100 bases:

>100_bases
TCGACGCCTCGATCTTTCCCGACAACATCACCGGCAACACCAACGCCGCCTCGGTCATGACCGGGTGGAAGGGTGCCGAA
CTGGTTCTGGAGGACCAAAA

Downstream 100 bases:

>100_bases
GCGAGAGCTACGCCTTCATCGGCCTCGGCCATCTCGGCGGCAACCTTGCCCCCAGCCTGATCCGCAACGGTTTTGCGATC
ACCGTCTTCGACCGCGACCC

Product: isomerase

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKITDVKTWVVGNPPPGIGGKYFIFVKLTTDGGVVGYGEAYNATFSAHVTAKMVEDMAERYLVGRDPHDIENFFRRAYSS
GFTQRPDVSGMGCFSALEMACWDIIGKEANKPVYKLLGGQVHETLRSYTYLYPHTGSVHSEDAPDGRNVYNDPELAAACA
LEYVEQGFNAVKLDPAGPYTAFDGHQPRLLDIDVSTRMIKAIREAVGTRADILFGTHGQFTASGALRMARAIEPYDPLWF
EEPVPPDMPEVMAQVARGTSIPIATGERLTTKFEFARVIENRAATILQPDLGRSGGILETKKIAAMAEAYHIQVAPHCYC
GPIVGAANIQLAVTLPNFLILESLKQWDGFHATLLKKKIEWQDGNVIPSKEPGLGVELNEAVCDAHPYTGKDLHLQMMQT
PLMP

Sequences:

>Translated_404_residues
MKITDVKTWVVGNPPPGIGGKYFIFVKLTTDGGVVGYGEAYNATFSAHVTAKMVEDMAERYLVGRDPHDIENFFRRAYSS
GFTQRPDVSGMGCFSALEMACWDIIGKEANKPVYKLLGGQVHETLRSYTYLYPHTGSVHSEDAPDGRNVYNDPELAAACA
LEYVEQGFNAVKLDPAGPYTAFDGHQPRLLDIDVSTRMIKAIREAVGTRADILFGTHGQFTASGALRMARAIEPYDPLWF
EEPVPPDMPEVMAQVARGTSIPIATGERLTTKFEFARVIENRAATILQPDLGRSGGILETKKIAAMAEAYHIQVAPHCYC
GPIVGAANIQLAVTLPNFLILESLKQWDGFHATLLKKKIEWQDGNVIPSKEPGLGVELNEAVCDAHPYTGKDLHLQMMQT
PLMP
>Mature_404_residues
MKITDVKTWVVGNPPPGIGGKYFIFVKLTTDGGVVGYGEAYNATFSAHVTAKMVEDMAERYLVGRDPHDIENFFRRAYSS
GFTQRPDVSGMGCFSALEMACWDIIGKEANKPVYKLLGGQVHETLRSYTYLYPHTGSVHSEDAPDGRNVYNDPELAAACA
LEYVEQGFNAVKLDPAGPYTAFDGHQPRLLDIDVSTRMIKAIREAVGTRADILFGTHGQFTASGALRMARAIEPYDPLWF
EEPVPPDMPEVMAQVARGTSIPIATGERLTTKFEFARVIENRAATILQPDLGRSGGILETKKIAAMAEAYHIQVAPHCYC
GPIVGAANIQLAVTLPNFLILESLKQWDGFHATLLKKKIEWQDGNVIPSKEPGLGVELNEAVCDAHPYTGKDLHLQMMQT
PLMP

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=410, Percent_Identity=21.9512195121951, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI186972148, Length=330, Percent_Identity=23.030303030303, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI48994953, Length=390, Percent_Identity=34.1025641025641, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787864, Length=383, Percent_Identity=26.8929503916449, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI226510960, Length=379, Percent_Identity=25.5936675461741, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 44376; Mature: 44376

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITDVKTWVVGNPPPGIGGKYFIFVKLTTDGGVVGYGEAYNATFSAHVTAKMVEDMAER
CCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCEEECCCCCCCEEEHHHHHHHHHHHHHH
YLVGRDPHDIENFFRRAYSSGFTQRPDVSGMGCFSALEMACWDIIGKEANKPVYKLLGGQ
HHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCHH
VHETLRSYTYLYPHTGSVHSEDAPDGRNVYNDPELAAACALEYVEQGFNAVKLDPAGPYT
HHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCC
AFDGHQPRLLDIDVSTRMIKAIREAVGTRADILFGTHGQFTASGALRMARAIEPYDPLWF
CCCCCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHCCCCCCCCC
EEPVPPDMPEVMAQVARGTSIPIATGERLTTKFEFARVIENRAATILQPDLGRSGGILET
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHH
KKIAAMAEAYHIQVAPHCYCGPIVGAANIQLAVTLPNFLILESLKQWDGFHATLLKKKIE
HHHHHHHHHEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHC
WQDGNVIPSKEPGLGVELNEAVCDAHPYTGKDLHLQMMQTPLMP
CCCCCCCCCCCCCCCEEHHHHHHCCCCCCCCCEEHHHHHCCCCC
>Mature Secondary Structure
MKITDVKTWVVGNPPPGIGGKYFIFVKLTTDGGVVGYGEAYNATFSAHVTAKMVEDMAER
CCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCEEECCCCCCCEEEHHHHHHHHHHHHHH
YLVGRDPHDIENFFRRAYSSGFTQRPDVSGMGCFSALEMACWDIIGKEANKPVYKLLGGQ
HHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCHH
VHETLRSYTYLYPHTGSVHSEDAPDGRNVYNDPELAAACALEYVEQGFNAVKLDPAGPYT
HHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCC
AFDGHQPRLLDIDVSTRMIKAIREAVGTRADILFGTHGQFTASGALRMARAIEPYDPLWF
CCCCCCCEEEEECHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHCCCCCCCCC
EEPVPPDMPEVMAQVARGTSIPIATGERLTTKFEFARVIENRAATILQPDLGRSGGILET
CCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHH
KKIAAMAEAYHIQVAPHCYCGPIVGAANIQLAVTLPNFLILESLKQWDGFHATLLKKKIE
HHHHHHHHHEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHC
WQDGNVIPSKEPGLGVELNEAVCDAHPYTGKDLHLQMMQTPLMP
CCCCCCCCCCCCCCCEEHHHHHHCCCCCCCCCEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA