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The map label for this gene is lrp [H]

Identifier: 13472305

GI number: 13472305

Start: 2070271

End: 2070750

Strand: Direct

Name: lrp [H]

Synonym: mlr2554

Alternate gene names: 13472305

Gene position: 2070271-2070750 (Clockwise)

Preceding gene: 13472302

Following gene: 13472306

Centisome position: 29.42

GC content: 65.83

Gene sequence:

>480_bases
ATGCCCCTGAAAGCCGACCTCGACGCCATCGACTGGAAGATCCTGCGCGAGCTGCAAGCGGATGGGCGCATGACCAATGT
CGAGCTGTCGAACCGCGTCGGCATTTCGGCCCCGCCCTGCCTGCGCAGGGTCAAGCGGCTGGAGGAGGCCGGCATCATCC
GCGGCTACCGCGCGCTGCTCAATGCCCCGGCGCTCGGCCTCGATGTCGTCGCCTTCTGCTTGGTCGGTCTGCATCACCAG
GCCGATGCCGAACTGCGCACCTTCGCCGAGCGCACGCGCGGCTGGCCGATCGTGCGCGATGCCTGGATGGTCTCGGGCGA
ATCCGATTTCCTGCTGCACTGCCTGGCAAGCGACCTCGGCGCCTTCCAGACCTTCGTCATCGAGGAACTGACCTCGACGC
CGAATGTCGACACCGTGCGCACCGCGCTCACCATCCGCCGCGTCAAGGATGAAGGCCTGGTTTCTTTCGAACGATCCTGA

Upstream 100 bases:

>100_bases
TCGTTACCGTTCAAAAATCGCATTGATGAGGGCTGGCGCCAACACAAAAGTCGTTTAATTACAAAATCGCGAAAGATTCT
TGCGCCGAGCTGAGACCGCC

Downstream 100 bases:

>100_bases
GGTCGCGCGAGCGCGTGAACGCTGGCGAATTCCTGGCCTTCGCCACACCGGCGCCGCGTTGGTATTCGACAGACGCTGAT
GTACAAGGCTGGACGGCTCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MPLKADLDAIDWKILRELQADGRMTNVELSNRVGISAPPCLRRVKRLEEAGIIRGYRALLNAPALGLDVVAFCLVGLHHQ
ADAELRTFAERTRGWPIVRDAWMVSGESDFLLHCLASDLGAFQTFVIEELTSTPNVDTVRTALTIRRVKDEGLVSFERS

Sequences:

>Translated_159_residues
MPLKADLDAIDWKILRELQADGRMTNVELSNRVGISAPPCLRRVKRLEEAGIIRGYRALLNAPALGLDVVAFCLVGLHHQ
ADAELRTFAERTRGWPIVRDAWMVSGESDFLLHCLASDLGAFQTFVIEELTSTPNVDTVRTALTIRRVKDEGLVSFERS
>Mature_158_residues
PLKADLDAIDWKILRELQADGRMTNVELSNRVGISAPPCLRRVKRLEEAGIIRGYRALLNAPALGLDVVAFCLVGLHHQA
DAELRTFAERTRGWPIVRDAWMVSGESDFLLHCLASDLGAFQTFVIEELTSTPNVDTVRTALTIRRVKDEGLVSFERS

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=145, Percent_Identity=40.6896551724138, Blast_Score=111, Evalue=2e-26,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17744; Mature: 17612

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKADLDAIDWKILRELQADGRMTNVELSNRVGISAPPCLRRVKRLEEAGIIRGYRALL
CCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAPALGLDVVAFCLVGLHHQADAELRTFAERTRGWPIVRDAWMVSGESDFLLHCLASDLG
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHEEECCCCHHHHHHHHHHHH
AFQTFVIEELTSTPNVDTVRTALTIRRVKDEGLVSFERS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
PLKADLDAIDWKILRELQADGRMTNVELSNRVGISAPPCLRRVKRLEEAGIIRGYRALL
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NAPALGLDVVAFCLVGLHHQADAELRTFAERTRGWPIVRDAWMVSGESDFLLHCLASDLG
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEHHHEEECCCCHHHHHHHHHHHH
AFQTFVIEELTSTPNVDTVRTALTIRRVKDEGLVSFERS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]