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The map label for this gene is ubiE [C]

Identifier: 13472006

GI number: 13472006

Start: 1755739

End: 1756335

Strand: Reverse

Name: ubiE [C]

Synonym: mll2162

Alternate gene names: 13472006

Gene position: 1756335-1755739 (Counterclockwise)

Preceding gene: 13472007

Following gene: 13472000

Centisome position: 24.96

GC content: 62.31

Gene sequence:

>597_bases
ATGACTGGAATGTTTCCCGCCACCTCCATGCCTGACCGCGATTGGTGGGAGGCGCTTTGGCCGGACCCGTCGGGCCTCTT
GCTGTCGTTGGGCGTTGAGCCGGGCATGACAGCTCTGGACCTGTGCTGTGGCGATGGCTATTTCACCGCTCCGCTTGCGA
AAATCGTCAGTGGCCGCGTCTATGCGCTCGACCTCGACCCGGAAATGATCGTGGCGGCCAAGGCCGAGGTGAAGCAGCTC
GGCGTTTCGGTCCTCAAGTGGATTGTCGCGGACGCCAGCGAAGTCGCGGAACTGATCCCCGAAAAAATCGATTTTGCCCT
GATCGCCAATACGTTCCACGGAGTGCCCGATCAGCCGGCCCTCGTCAAAGCGGTCGCCCGTACGCTTAAGCCGCGCGGTC
TGTTTGCGCTTGTCAATTGGCATCGGCTGCCGCGAGAGCAGACGACCGTGCTTGGTCAGCCGCGCGGCCCCAGGACGGAG
ATGCGCATGTCACCCGAAGCGGTGGCGGCGGTTCTGGAGGCTACTGGTTTCCGGCTTCTGCGAATGGTCGATTTGCCGCC
GTATCACTACGGGGCGGTGTTCGAACACAAGGGATGA

Upstream 100 bases:

>100_bases
TGACCGCCATCACTTCGATCCGCCGTCGGCAACGAAAGCGTTGCCTTTGTCGGCCTGCCAGTCAAAGCTGCCCAACAGCG
CAATTCTAGAGCGTCCGCCC

Downstream 100 bases:

>100_bases
TGCGGAAGTTTCCCGGCTCAGACACCGGCGCCTGTTCCAGGACTCCGGATCGGCCGCTACCCCAAAGTGAACGCGCCGAT
GCTGCGGTAGAGGACATAGC

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: SAM-Dependent Methyltransferase; Methyltransferase; Methyltransferase Domain Protein; Methyltransferase UbiE/COQ5 Family; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Methyltransferase Domain Family

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTGMFPATSMPDRDWWEALWPDPSGLLLSLGVEPGMTALDLCCGDGYFTAPLAKIVSGRVYALDLDPEMIVAAKAEVKQL
GVSVLKWIVADASEVAELIPEKIDFALIANTFHGVPDQPALVKAVARTLKPRGLFALVNWHRLPREQTTVLGQPRGPRTE
MRMSPEAVAAVLEATGFRLLRMVDLPPYHYGAVFEHKG

Sequences:

>Translated_198_residues
MTGMFPATSMPDRDWWEALWPDPSGLLLSLGVEPGMTALDLCCGDGYFTAPLAKIVSGRVYALDLDPEMIVAAKAEVKQL
GVSVLKWIVADASEVAELIPEKIDFALIANTFHGVPDQPALVKAVARTLKPRGLFALVNWHRLPREQTTVLGQPRGPRTE
MRMSPEAVAAVLEATGFRLLRMVDLPPYHYGAVFEHKG
>Mature_197_residues
TGMFPATSMPDRDWWEALWPDPSGLLLSLGVEPGMTALDLCCGDGYFTAPLAKIVSGRVYALDLDPEMIVAAKAEVKQLG
VSVLKWIVADASEVAELIPEKIDFALIANTFHGVPDQPALVKAVARTLKPRGLFALVNWHRLPREQTTVLGQPRGPRTEM
RMSPEAVAAVLEATGFRLLRMVDLPPYHYGAVFEHKG

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21678; Mature: 21546

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMFPATSMPDRDWWEALWPDPSGLLLSLGVEPGMTALDLCCGDGYFTAPLAKIVSGRV
CCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHCCCE
YALDLDPEMIVAAKAEVKQLGVSVLKWIVADASEVAELIPEKIDFALIANTFHGVPDQPA
EEEECCCCEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LVKAVARTLKPRGLFALVNWHRLPREQTTVLGQPRGPRTEMRMSPEAVAAVLEATGFRLL
HHHHHHHHCCCCCEEEEEHHHHCCCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEE
RMVDLPPYHYGAVFEHKG
HEECCCCCCCCEEEECCC
>Mature Secondary Structure 
TGMFPATSMPDRDWWEALWPDPSGLLLSLGVEPGMTALDLCCGDGYFTAPLAKIVSGRV
CCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHCCCE
YALDLDPEMIVAAKAEVKQLGVSVLKWIVADASEVAELIPEKIDFALIANTFHGVPDQPA
EEEECCCCEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LVKAVARTLKPRGLFALVNWHRLPREQTTVLGQPRGPRTEMRMSPEAVAAVLEATGFRLL
HHHHHHHHCCCCCEEEEEHHHHCCCHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEE
RMVDLPPYHYGAVFEHKG
HEECCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA