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The map label for this gene is yusZ [H]

Identifier: 13471868

GI number: 13471868

Start: 1626440

End: 1627333

Strand: Reverse

Name: yusZ [H]

Synonym: mll1982

Alternate gene names: 13471868

Gene position: 1627333-1626440 (Counterclockwise)

Preceding gene: 13471869

Following gene: 13471867

Centisome position: 23.13

GC content: 68.68

Gene sequence:

>894_bases
ATGAAACGGACAATCCTGATCACCGGCGCCTCCAGCGGTTTTGGCGCGATGACTGCGCGGGCGCTCGCAAGAGCCGGCCA
CACAGTCTTTGCCTCGATGCGTGATCCCTCGGCACGCGGTGGTGCGGCGGCAGCCGAAATGGAGGCGCTTGCGCGTGACG
AGGGCGTGGTGCTCAAGCCCATCGCGCTCGACGTCACCTCCGATGGCTCTGCAGAAGCGGCGATCCGGCGGATCCTCGGC
GAAGCCGGCCGGCTCGACGTGCTGATCCACAATGCCGGGCATATGGGGTTCGGGCCGGCCGAGGCGTTTTCGCCCGAACA
GCTGACGCAGCTCTATGACGTCAATGTCGTCGGCACGCAGCGCGTCAATCGGGCTGCCCTGCCGCATATGCGGTCTCTCG
GCCGGGCGCAGATGATCTGGGTCGGTTCGAGCAGCACGCGCGGCGGCACGCCGCCCTTCCTGGCCCCCTATTTCGCGGCC
AAGGCCGGCATGGACGCGCTGGCGCAGAGCTATGCGCTGGAACTCGCCCGCTTCGGCATCGAAACGACGATCGTGGTGCC
GGGCGCCTTCACCAAGGGCACGGAGCATTTCCACCACGCGGCGGCACCCGCCGATGCCGAGCGCGCCGGCGCCTATTGGT
CCGGTCCCTATGCCGGTGCCGACCAGCAGGCGCTGAAGGGGCTGGCGTCGCTGGAACCGGCGGATGCCGATCCGGCCGAG
GTCGCCGAGGCAATCGTCGACCTCGTCGCCATGCCGCATGGCAGCCGCCCGCTGCGCGTTCATATCGATCCCTCCGACGA
TGGCGCCGCGATCGTCAACGGCGTTGCCGACCGCGTGCGCGCGCAACTCCTGGAGCGGATCGGCCTTGCCGACCTGCTCC
ATCCCAAAGCCTGA

Upstream 100 bases:

>100_bases
ACATTGCCGGCGTCGTGTCGTTCCTGGCCGGGCCGGACAGTGGCTGGGTCAACGGACAGATCATCCGCGCCAATGGCGGC
GTGATCTGAGGGAGGCCGAG

Downstream 100 bases:

>100_bases
AAACCCAACCCCAACAGAAAAGGAAACCATCATGCCATTCGCCAACATCAAGCTGCCGCAGGCCGCTCTCTCCAAGGCGC
AGAAAGAAGACCTCATCCAT

Product: short chain oxidoreductase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKRTILITGASSGFGAMTARALARAGHTVFASMRDPSARGGAAAAEMEALARDEGVVLKPIALDVTSDGSAEAAIRRILG
EAGRLDVLIHNAGHMGFGPAEAFSPEQLTQLYDVNVVGTQRVNRAALPHMRSLGRAQMIWVGSSSTRGGTPPFLAPYFAA
KAGMDALAQSYALELARFGIETTIVVPGAFTKGTEHFHHAAAPADAERAGAYWSGPYAGADQQALKGLASLEPADADPAE
VAEAIVDLVAMPHGSRPLRVHIDPSDDGAAIVNGVADRVRAQLLERIGLADLLHPKA

Sequences:

>Translated_297_residues
MKRTILITGASSGFGAMTARALARAGHTVFASMRDPSARGGAAAAEMEALARDEGVVLKPIALDVTSDGSAEAAIRRILG
EAGRLDVLIHNAGHMGFGPAEAFSPEQLTQLYDVNVVGTQRVNRAALPHMRSLGRAQMIWVGSSSTRGGTPPFLAPYFAA
KAGMDALAQSYALELARFGIETTIVVPGAFTKGTEHFHHAAAPADAERAGAYWSGPYAGADQQALKGLASLEPADADPAE
VAEAIVDLVAMPHGSRPLRVHIDPSDDGAAIVNGVADRVRAQLLERIGLADLLHPKA
>Mature_297_residues
MKRTILITGASSGFGAMTARALARAGHTVFASMRDPSARGGAAAAEMEALARDEGVVLKPIALDVTSDGSAEAAIRRILG
EAGRLDVLIHNAGHMGFGPAEAFSPEQLTQLYDVNVVGTQRVNRAALPHMRSLGRAQMIWVGSSSTRGGTPPFLAPYFAA
KAGMDALAQSYALELARFGIETTIVVPGAFTKGTEHFHHAAAPADAERAGAYWSGPYAGADQQALKGLASLEPADADPAE
VAEAIVDLVAMPHGSRPLRVHIDPSDDGAAIVNGVADRVRAQLLERIGLADLLHPKA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=263, Percent_Identity=29.6577946768061, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI223718074, Length=192, Percent_Identity=37.5, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI22507405, Length=195, Percent_Identity=31.7948717948718, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI44680136, Length=213, Percent_Identity=30.5164319248826, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI44680133, Length=213, Percent_Identity=30.5164319248826, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI17738292, Length=213, Percent_Identity=30.5164319248826, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI119392083, Length=196, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI150247226, Length=192, Percent_Identity=30.7291666666667, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI19743808, Length=195, Percent_Identity=30.2564102564103, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=30.8510638297872, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4504503, Length=195, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=209, Percent_Identity=29.6650717703349, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786701, Length=227, Percent_Identity=25.9911894273128, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787335, Length=208, Percent_Identity=29.3269230769231, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=251, Percent_Identity=25.8964143426295, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788459, Length=208, Percent_Identity=27.8846153846154, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786812, Length=188, Percent_Identity=28.1914893617021, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=210, Percent_Identity=29.5238095238095, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534660, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=184, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17557780, Length=194, Percent_Identity=30.4123711340206, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=251, Percent_Identity=27.8884462151394, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=200, Percent_Identity=31, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=27.2277227722772, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=30.8080808080808, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=207, Percent_Identity=26.5700483091787, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=30.5220883534137, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24651139, Length=246, Percent_Identity=28.0487804878049, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571526, Length=198, Percent_Identity=30.3030303030303, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643142, Length=186, Percent_Identity=30.6451612903226, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644339, Length=209, Percent_Identity=31.1004784688995, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356301, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30925; Mature: 30925

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTILITGASSGFGAMTARALARAGHTVFASMRDPSARGGAAAAEMEALARDEGVVLKP
CCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEE
IALDVTSDGSAEAAIRRILGEAGRLDVLIHNAGHMGFGPAEAFSPEQLTQLYDVNVVGTQ
EEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHCCCHHHHHHHHCCEEECHH
RVNRAALPHMRSLGRAQMIWVGSSSTRGGTPPFLAPYFAAKAGMDALAQSYALELARFGI
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETTIVVPGAFTKGTEHFHHAAAPADAERAGAYWSGPYAGADQQALKGLASLEPADADPAE
EEEEEECCCCCCCHHHHHHHCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHH
VAEAIVDLVAMPHGSRPLRVHIDPSDDGAAIVNGVADRVRAQLLERIGLADLLHPKA
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCC
>Mature Secondary Structure
MKRTILITGASSGFGAMTARALARAGHTVFASMRDPSARGGAAAAEMEALARDEGVVLKP
CCEEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEE
IALDVTSDGSAEAAIRRILGEAGRLDVLIHNAGHMGFGPAEAFSPEQLTQLYDVNVVGTQ
EEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHCCCHHHHHHHHCCEEECHH
RVNRAALPHMRSLGRAQMIWVGSSSTRGGTPPFLAPYFAAKAGMDALAQSYALELARFGI
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETTIVVPGAFTKGTEHFHHAAAPADAERAGAYWSGPYAGADQQALKGLASLEPADADPAE
EEEEEECCCCCCCHHHHHHHCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHH
VAEAIVDLVAMPHGSRPLRVHIDPSDDGAAIVNGVADRVRAQLLERIGLADLLHPKA
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]