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The map label for this gene is gcvT [H]

Identifier: 13471340

GI number: 13471340

Start: 1083670

End: 1086117

Strand: Direct

Name: gcvT [H]

Synonym: mlr1283

Alternate gene names: 13471340

Gene position: 1083670-1086117 (Clockwise)

Preceding gene: 13471339

Following gene: 13471352

Centisome position: 15.4

GC content: 63.64

Gene sequence:

>2448_bases
ATGACCAGGACCATCCCCACCAAGGCCCGCGCGGTGATCATCGGCGGCGGCGTTTCCGGCTGTTCGGTCGCCTACCATCT
GGCCAAGCTCGGCTGGACCGATATCGTGCTCCTGGAACGCAAGCAGCTGACCTCGGGCACGACCTGGCATGCTGCCGGCC
TGATCGGTCAGTTGCGCGGCTCGCAGAACATGACGCGGCTGGCGAAATATTCGGCCGACCTCTACGTCAAGCTGGAAGCC
GAGACCGAGGTCGGCACCGGCATGCGCCAGGTCGGCTCGATCACGGTCGCGCTGACCGAGGAGCGCAAGCACGAGATCTA
CCGGCAGGCGTCGCTGGCGCGTGCCTTCGACGTCGATGTGCGCGAGATTTCGCCGAATGAAGTCAAAGAGATGTATCCGC
ATCTCAATGTATCAGACGTCGTCGGCGCCGTGCATCTGCCGCTCGACGGCCAGTGCGACCCCGCCAACATCGCCATGGCG
CTGGCCAAAGGCGCACGCCAGCGCGGCGCCACCATCGTCGAGAATGTGAAGGTCACCAAGGTCCACACCAGGGATGGTCG
CGTTACAGGCGTGTCCTGGGCGCAGGGTGACGAACAAGGCATGATCGAGGCCGACATTGTCGTCAACTGCGCCGGCATGT
GGGCGCGTGAATTGGGCGCCCAGAACGGCGTCACCATCCCGCTGCACGCCTGCGAGCATTTTTATCTCGTCACCGAGCCG
ATCCCCGGCCTCAGCCGACTGCCGGTGCTGCGTGTACCGGACGAGTGCGCCTACTACAAGGAAGACGCCGGCAAGATGAT
GCTCGGCGCCTTCGAGCCGGTGGCCAAGCCATGGGGCATGGACGGCATCCGCGAGGATTTCTGCTTCGACCAGTTGCCCG
AAGATATGGACCATTTCGAACCGATCCTCGAAATGGGTGTCAACCGCATGCCGATGCTGGCGACCGCCGGCATCCACACC
TTCTTCAACGGCCCCGAAAGTTTCACGCCGGACGACCGCTACTATCTCGGCGAGGCGCCGGAACTGCGGGGCTACTGGAT
GGCGACCGGCTACAATTCGATCGGCATCGTCTCCTCCGGCGGCGCCGGCATGGCGCTGGCGCAGTGGATCAACGATGGCG
AAGCGCCGTTCGACCTCTGGGAAGTCGACATCCGCCGCGCCCAGCCGTTCCAGAAGAACCGCCGCTATCTCAAACAGCGC
GTCTCCGAAACGCTCGGACTGCTTTACGCCGACCATTTCCCCTATCGGCAGATGGCGACATCGCGTGGCGTGCGCCGCTC
GCCCCTGCATGAGCACCTGAAGGCGCGCGGTGCCGTGTTCGGCGAGGTCGCCGGCTGGGAGCGCGCCAACTGGTTCGCAC
GGGAGGGCCAGGAGCGCGAGTACCGCTATTCCTGGAAGCGGCAGAACTGGTTCGACAACCAGCGCGAGGAGCATCTGGCG
GTCCGCAACAAGGTCGGTCTGTTCGACATGACCTCGTTCGGCAAGATCCGCGTCGAGGGTCGCGATGCCTGCGCTTTCCT
GCAAAGGCTGTGCGCCAACGACATGGACGTGGCGCCGGGCAAGATCATCTACACGCAAATGCTCAACCAGCGCGGCGGCA
TCGAGAGCGATCTCACCGTGTCCAGGCTTTCGGATACGGCCTACTTCCTCGTTGTGCCCGGTGCCACGCTGCAGCGCGAT
CTGGCTTGGCTGCGCCGGCATGTCGGTGAAGAGTTCGTGGTCATCACCGATGTTACGGCGGCTGAAAGCGTGCTCTGCCT
GATGGGTCCGGATGCGCGAAAGCTGATCCAGAAAGTCAGTCCCAACGATTTCTCCAACGAGAACAACCCGTTCGGCACGT
TCCAGGAGATCGAGATCGGCATGGGGCTGGCCCGCGCCCACCGCGTCACCTATGTCGGCGAACTCGGCTGGGAGCTCTAT
GTCTCGACCGACCAGGCGGCACATATCTTCGAGGCGATCGACGAGGCCGGCGCCGATGTCGGCCTGAAACTCTGCGGCCT
GCACACGCTGGATTCCTGCCGTATCGAAAAGGCTTTCCGGCATTTCGGCCACGACATCACCGACGAGGACAATGTGCTGG
AAGCAGGCCTCGGCTTCGCGGTGAAGACGGCCAAGGGTGATTTCATCGGTCGCGATGCCGTGCTGAAGAAGAAAGACGCC
GGATTGAACCGCCGGCTGGTCCAGTTCCGGCTGAAAGACCCGCAGCCCCTGCTCTTCCACAATGAAGCCATCCTGCGCGA
CGGTAGGATCGTCGGCCCGATCACCTCGGGCAATTACGGCCACCACCTCGGCGGCGCCATTGGGCTCGGCTATGTGCCGT
GCCCGGGCGAGAGCGAGGCGGATGTGCTGGCCTCATCCTACGAGATCGAGATCGCCGGCGAACGGTTTGCGGCGGAGGCC
TCGCTGAAGCCGATGTATGATCCGAAGGCGGAAAGGGTGAAGATGTAG

Upstream 100 bases:

>100_bases
CCGGCCACATCCGCATCAGCCTCTGCCAGCCGGAGCCCGTACTGCAGGAGGCCGCCGCTCGGCTGCGCCGTTTTGCTTCC
ACCTATCGCCGCGAGGCCGC

Downstream 100 bases:

>100_bases
CCCTCCACCTTCTCCGCTTGTGGGAGAAGGTGGATCGGCGCGTAGCGCCGAGACGGATGAGCGACTATCTGAGGTGTCAA
GTTGCATTTGCGAATTCGTT

Product: sarcosine dehydrogenase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MTRTIPTKARAVIIGGGVSGCSVAYHLAKLGWTDIVLLERKQLTSGTTWHAAGLIGQLRGSQNMTRLAKYSADLYVKLEA
ETEVGTGMRQVGSITVALTEERKHEIYRQASLARAFDVDVREISPNEVKEMYPHLNVSDVVGAVHLPLDGQCDPANIAMA
LAKGARQRGATIVENVKVTKVHTRDGRVTGVSWAQGDEQGMIEADIVVNCAGMWARELGAQNGVTIPLHACEHFYLVTEP
IPGLSRLPVLRVPDECAYYKEDAGKMMLGAFEPVAKPWGMDGIREDFCFDQLPEDMDHFEPILEMGVNRMPMLATAGIHT
FFNGPESFTPDDRYYLGEAPELRGYWMATGYNSIGIVSSGGAGMALAQWINDGEAPFDLWEVDIRRAQPFQKNRRYLKQR
VSETLGLLYADHFPYRQMATSRGVRRSPLHEHLKARGAVFGEVAGWERANWFAREGQEREYRYSWKRQNWFDNQREEHLA
VRNKVGLFDMTSFGKIRVEGRDACAFLQRLCANDMDVAPGKIIYTQMLNQRGGIESDLTVSRLSDTAYFLVVPGATLQRD
LAWLRRHVGEEFVVITDVTAAESVLCLMGPDARKLIQKVSPNDFSNENNPFGTFQEIEIGMGLARAHRVTYVGELGWELY
VSTDQAAHIFEAIDEAGADVGLKLCGLHTLDSCRIEKAFRHFGHDITDEDNVLEAGLGFAVKTAKGDFIGRDAVLKKKDA
GLNRRLVQFRLKDPQPLLFHNEAILRDGRIVGPITSGNYGHHLGGAIGLGYVPCPGESEADVLASSYEIEIAGERFAAEA
SLKPMYDPKAERVKM

Sequences:

>Translated_815_residues
MTRTIPTKARAVIIGGGVSGCSVAYHLAKLGWTDIVLLERKQLTSGTTWHAAGLIGQLRGSQNMTRLAKYSADLYVKLEA
ETEVGTGMRQVGSITVALTEERKHEIYRQASLARAFDVDVREISPNEVKEMYPHLNVSDVVGAVHLPLDGQCDPANIAMA
LAKGARQRGATIVENVKVTKVHTRDGRVTGVSWAQGDEQGMIEADIVVNCAGMWARELGAQNGVTIPLHACEHFYLVTEP
IPGLSRLPVLRVPDECAYYKEDAGKMMLGAFEPVAKPWGMDGIREDFCFDQLPEDMDHFEPILEMGVNRMPMLATAGIHT
FFNGPESFTPDDRYYLGEAPELRGYWMATGYNSIGIVSSGGAGMALAQWINDGEAPFDLWEVDIRRAQPFQKNRRYLKQR
VSETLGLLYADHFPYRQMATSRGVRRSPLHEHLKARGAVFGEVAGWERANWFAREGQEREYRYSWKRQNWFDNQREEHLA
VRNKVGLFDMTSFGKIRVEGRDACAFLQRLCANDMDVAPGKIIYTQMLNQRGGIESDLTVSRLSDTAYFLVVPGATLQRD
LAWLRRHVGEEFVVITDVTAAESVLCLMGPDARKLIQKVSPNDFSNENNPFGTFQEIEIGMGLARAHRVTYVGELGWELY
VSTDQAAHIFEAIDEAGADVGLKLCGLHTLDSCRIEKAFRHFGHDITDEDNVLEAGLGFAVKTAKGDFIGRDAVLKKKDA
GLNRRLVQFRLKDPQPLLFHNEAILRDGRIVGPITSGNYGHHLGGAIGLGYVPCPGESEADVLASSYEIEIAGERFAAEA
SLKPMYDPKAERVKM
>Mature_814_residues
TRTIPTKARAVIIGGGVSGCSVAYHLAKLGWTDIVLLERKQLTSGTTWHAAGLIGQLRGSQNMTRLAKYSADLYVKLEAE
TEVGTGMRQVGSITVALTEERKHEIYRQASLARAFDVDVREISPNEVKEMYPHLNVSDVVGAVHLPLDGQCDPANIAMAL
AKGARQRGATIVENVKVTKVHTRDGRVTGVSWAQGDEQGMIEADIVVNCAGMWARELGAQNGVTIPLHACEHFYLVTEPI
PGLSRLPVLRVPDECAYYKEDAGKMMLGAFEPVAKPWGMDGIREDFCFDQLPEDMDHFEPILEMGVNRMPMLATAGIHTF
FNGPESFTPDDRYYLGEAPELRGYWMATGYNSIGIVSSGGAGMALAQWINDGEAPFDLWEVDIRRAQPFQKNRRYLKQRV
SETLGLLYADHFPYRQMATSRGVRRSPLHEHLKARGAVFGEVAGWERANWFAREGQEREYRYSWKRQNWFDNQREEHLAV
RNKVGLFDMTSFGKIRVEGRDACAFLQRLCANDMDVAPGKIIYTQMLNQRGGIESDLTVSRLSDTAYFLVVPGATLQRDL
AWLRRHVGEEFVVITDVTAAESVLCLMGPDARKLIQKVSPNDFSNENNPFGTFQEIEIGMGLARAHRVTYVGELGWELYV
STDQAAHIFEAIDEAGADVGLKLCGLHTLDSCRIEKAFRHFGHDITDEDNVLEAGLGFAVKTAKGDFIGRDAVLKKKDAG
LNRRLVQFRLKDPQPLLFHNEAILRDGRIVGPITSGNYGHHLGGAIGLGYVPCPGESEADVLASSYEIEIAGERFAAEAS
LKPMYDPKAERVKM

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=863, Percent_Identity=37.0799536500579, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI21361378, Length=863, Percent_Identity=37.0799536500579, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI194306651, Length=825, Percent_Identity=37.5757575757576, Blast_Score=501, Evalue=1e-141,
Organism=Homo sapiens, GI24797151, Length=818, Percent_Identity=34.3520782396088, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI44662838, Length=359, Percent_Identity=26.7409470752089, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI257796258, Length=359, Percent_Identity=26.7409470752089, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI257796256, Length=291, Percent_Identity=27.1477663230241, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI257796254, Length=356, Percent_Identity=24.1573033707865, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789272, Length=325, Percent_Identity=29.2307692307692, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1787438, Length=316, Percent_Identity=25.6329113924051, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563613, Length=833, Percent_Identity=33.0132052821128, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71994045, Length=831, Percent_Identity=29.0012033694344, Blast_Score=295, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI71994052, Length=838, Percent_Identity=28.7589498806683, Blast_Score=292, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI17560118, Length=362, Percent_Identity=25.414364640884, Blast_Score=88, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320222, Length=243, Percent_Identity=26.3374485596708, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28571104, Length=845, Percent_Identity=34.5562130177515, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI20130091, Length=860, Percent_Identity=32.6744186046512, Blast_Score=428, Evalue=1e-120,
Organism=Drosophila melanogaster, GI20129441, Length=337, Percent_Identity=29.3768545994065, Blast_Score=117, Evalue=4e-26,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 90557; Mature: 90426

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTIPTKARAVIIGGGVSGCSVAYHLAKLGWTDIVLLERKQLTSGTTWHAAGLIGQLRG
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHHHHHHHCC
SQNMTRLAKYSADLYVKLEAETEVGTGMRQVGSITVALTEERKHEIYRQASLARAFDVDV
CCHHHHHHHCCCEEEEEEEECCCCCCCHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCH
REISPNEVKEMYPHLNVSDVVGAVHLPLDGQCDPANIAMALAKGARQRGATIVENVKVTK
HCCCHHHHHHHCCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCEECCCEEEEE
VHTRDGRVTGVSWAQGDEQGMIEADIVVNCAGMWARELGAQNGVTIPLHACEHFYLVTEP
EECCCCEEEEEEECCCCCCCCEEEEEEEEEHHHHHHHHCCCCCCEEEEECCCEEEEEECC
IPGLSRLPVLRVPDECAYYKEDAGKMMLGAFEPVAKPWGMDGIREDFCFDQLPEDMDHFE
CCCCCCCCEEECCHHHHHHHHCCCCEEEECCCHHCCCCCCCCCHHHHHHHHCCHHHHHHH
PILEMGVNRMPMLATAGIHTFFNGPESFTPDDRYYLGEAPELRGYWMATGYNSIGIVSSG
HHHHHCCCCCCCHHHHCHHHHCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCEEEEECC
GAGMALAQWINDGEAPFDLWEVDIRRAQPFQKNRRYLKQRVSETLGLLYADHFPYRQMAT
CCCHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SRGVRRSPLHEHLKARGAVFGEVAGWERANWFAREGQEREYRYSWKRQNWFDNQREEHLA
HCCCCCCHHHHHHHHCCCEEEHHCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHH
VRNKVGLFDMTSFGKIRVEGRDACAFLQRLCANDMDVAPGKIIYTQMLNQRGGIESDLTV
HHHCCCEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
SRLSDTAYFLVVPGATLQRDLAWLRRHVGEEFVVITDVTAAESVLCLMGPDARKLIQKVS
EECCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHCEEEEECCCHHHHHHHCC
PNDFSNENNPFGTFQEIEIGMGLARAHRVTYVGELGWELYVSTDQAAHIFEAIDEAGADV
CCCCCCCCCCCCCHHHHHHCCCHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHCCCCC
GLKLCGLHTLDSCRIEKAFRHFGHDITDEDNVLEAGLGFAVKTAKGDFIGRDAVLKKKDA
CEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCCCHHHCCCCC
GLNRRLVQFRLKDPQPLLFHNEAILRDGRIVGPITSGNYGHHLGGAIGLGYVPCPGESEA
CCCCEEEEEEECCCCCEEEECCHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCCH
DVLASSYEIEIAGERFAAEASLKPMYDPKAERVKM
HHHHCCEEEEECCCHHCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TRTIPTKARAVIIGGGVSGCSVAYHLAKLGWTDIVLLERKQLTSGTTWHAAGLIGQLRG
CCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCHHHHHHHHHCC
SQNMTRLAKYSADLYVKLEAETEVGTGMRQVGSITVALTEERKHEIYRQASLARAFDVDV
CCHHHHHHHCCCEEEEEEEECCCCCCCHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCH
REISPNEVKEMYPHLNVSDVVGAVHLPLDGQCDPANIAMALAKGARQRGATIVENVKVTK
HCCCHHHHHHHCCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCEECCCEEEEE
VHTRDGRVTGVSWAQGDEQGMIEADIVVNCAGMWARELGAQNGVTIPLHACEHFYLVTEP
EECCCCEEEEEEECCCCCCCCEEEEEEEEEHHHHHHHHCCCCCCEEEEECCCEEEEEECC
IPGLSRLPVLRVPDECAYYKEDAGKMMLGAFEPVAKPWGMDGIREDFCFDQLPEDMDHFE
CCCCCCCCEEECCHHHHHHHHCCCCEEEECCCHHCCCCCCCCCHHHHHHHHCCHHHHHHH
PILEMGVNRMPMLATAGIHTFFNGPESFTPDDRYYLGEAPELRGYWMATGYNSIGIVSSG
HHHHHCCCCCCCHHHHCHHHHCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCEEEEECC
GAGMALAQWINDGEAPFDLWEVDIRRAQPFQKNRRYLKQRVSETLGLLYADHFPYRQMAT
CCCHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SRGVRRSPLHEHLKARGAVFGEVAGWERANWFAREGQEREYRYSWKRQNWFDNQREEHLA
HCCCCCCHHHHHHHHCCCEEEHHCCCCHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHH
VRNKVGLFDMTSFGKIRVEGRDACAFLQRLCANDMDVAPGKIIYTQMLNQRGGIESDLTV
HHHCCCEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
SRLSDTAYFLVVPGATLQRDLAWLRRHVGEEFVVITDVTAAESVLCLMGPDARKLIQKVS
EECCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECHHHHCEEEEECCCHHHHHHHCC
PNDFSNENNPFGTFQEIEIGMGLARAHRVTYVGELGWELYVSTDQAAHIFEAIDEAGADV
CCCCCCCCCCCCCHHHHHHCCCHHHHHHEEEEECCCEEEEEECCHHHHHHHHHHHCCCCC
GLKLCGLHTLDSCRIEKAFRHFGHDITDEDNVLEAGLGFAVKTAKGDFIGRDAVLKKKDA
CEEEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEECCCCCCCCCHHHCCCCC
GLNRRLVQFRLKDPQPLLFHNEAILRDGRIVGPITSGNYGHHLGGAIGLGYVPCPGESEA
CCCCEEEEEEECCCCCEEEECCHHHCCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCCH
DVLASSYEIEIAGERFAAEASLKPMYDPKAERVKM
HHHHCCEEEEECCCHHCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA