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The map label for this gene is yfkF [H]

Identifier: 13470992

GI number: 13470992

Start: 675158

End: 676336

Strand: Direct

Name: yfkF [H]

Synonym: mlr0845

Alternate gene names: 13470992

Gene position: 675158-676336 (Clockwise)

Preceding gene: 13470991

Following gene: 13470993

Centisome position: 9.6

GC content: 64.21

Gene sequence:

>1179_bases
ATGACGGTCGATACCCAACCACAGGGCGACGAACGCGTACACTGGCTGCCGATGGTGGCGGCGATCTCGTCAATCAGCGT
CGTCGGCATCGCCATTGGCCTCGGCATGCCACTGCTCAGCGTCATCCTGGAAACGCGCGGCCACTCGGCTTCGATGATCG
GCCTCAACACCGCCGTGGCCGGCCTGGCCTCGATCGCCGGTGCGCCGCTGGCGACACCGCTCGCCATGCGCTTTGGCGTC
GCCTGGACCATGATCGCCATGATTGCCACCGGCGCTCTCGCCTTCGTCGGTTTCCATTTCGCGCCCAATTTCTGGATGTG
GTTCCCGCTGCGCATCGTGCTGCATATCGCGTTGACGGTGCTGTTCATCCTGTCGGAATTCTGGATCAGCACGTCGGCAC
CGCCGCACCGGCGCGGCCTTGTTCTTGGCATCTACGCCACCGTCCTGTCGCTCGGTTTTGCCGCCGGACCGTGGCTGTTC
GCCCATCTCGGCAGCTCCGGCTTCAGGCCGTTCGGCGTCATCATCGCACTGGTCACGCTGGCCGCGATACCGGTGCTGGC
CGCGCGCAATGAAAGCCCCTCCATCGTCGCCGATGGCGAAACCAGCAATTTCCTGCGCTACATCTGGCTGGTGCCGACCG
CGACTTTTGCCGTGCTGGTGTTCGGCGCGGTCGAGACCGGCGGCTTCGCGCTGTTCCCGGTCTATGGCAACCGCATCGGC
TATTCCGAAGCCGACGCCGCATTGCTGCTGACCATGATCGGCCTTGGCAATGTGCTCTTGCAGATTCCGATCGGCATGAT
CAGCGACCGCGTTTCGGACCGGCGTTATCTGCTGCTCGCCTGCGCCACGGTTGGCCTTGCCGGCACGCTGTTCATGCCCT
TCTTTGCGGCGAACTGGCACTTGATGGCAGCGCTTCTGTTCGTCTGGGGCGGTGTCGTCGCGGCCATGTACACGATCGGC
CTCGCCCATCTCGGTTCGCAGCTCTCCGGCCACGAACTGGCGTCGGCCAACGCAGCCTTCGTGCTGTGCTACGGCGTCGG
CATGGTGCTTGGCCCACAGGCGATCGGCATCGGCATGGACAGTTTCGGGCCTTCCGGTTTCGGCTGGTCGCTCGGCCTGT
TCTTCGGCGCCTACATCGCCCTGGTCTGCTTCAGGCTGGTTCGCAAGATCCTTTTGTAG

Upstream 100 bases:

>100_bases
CTTCACCCGCGAACTTCTGTAGAGCAATTCCAGGAAGAGTGTGACGCGGTTTTCCGCCCGGAATTGCGTAAGATCAACGA
GACAGAGTATTCACTATCCC

Downstream 100 bases:

>100_bases
AGCGTCTGGAATAGCGATTCTGTTCGCGTACGCAGCAGCTGCTGACAGAACCGTGTCAGGAGCCACGCGGTAAAAGAGTA
TCCCCAAAACATCGGAAGTT

Product: multidrug-efflux transporter lile protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTVDTQPQGDERVHWLPMVAAISSISVVGIAIGLGMPLLSVILETRGHSASMIGLNTAVAGLASIAGAPLATPLAMRFGV
AWTMIAMIATGALAFVGFHFAPNFWMWFPLRIVLHIALTVLFILSEFWISTSAPPHRRGLVLGIYATVLSLGFAAGPWLF
AHLGSSGFRPFGVIIALVTLAAIPVLAARNESPSIVADGETSNFLRYIWLVPTATFAVLVFGAVETGGFALFPVYGNRIG
YSEADAALLLTMIGLGNVLLQIPIGMISDRVSDRRYLLLACATVGLAGTLFMPFFAANWHLMAALLFVWGGVVAAMYTIG
LAHLGSQLSGHELASANAAFVLCYGVGMVLGPQAIGIGMDSFGPSGFGWSLGLFFGAYIALVCFRLVRKILL

Sequences:

>Translated_392_residues
MTVDTQPQGDERVHWLPMVAAISSISVVGIAIGLGMPLLSVILETRGHSASMIGLNTAVAGLASIAGAPLATPLAMRFGV
AWTMIAMIATGALAFVGFHFAPNFWMWFPLRIVLHIALTVLFILSEFWISTSAPPHRRGLVLGIYATVLSLGFAAGPWLF
AHLGSSGFRPFGVIIALVTLAAIPVLAARNESPSIVADGETSNFLRYIWLVPTATFAVLVFGAVETGGFALFPVYGNRIG
YSEADAALLLTMIGLGNVLLQIPIGMISDRVSDRRYLLLACATVGLAGTLFMPFFAANWHLMAALLFVWGGVVAAMYTIG
LAHLGSQLSGHELASANAAFVLCYGVGMVLGPQAIGIGMDSFGPSGFGWSLGLFFGAYIALVCFRLVRKILL
>Mature_391_residues
TVDTQPQGDERVHWLPMVAAISSISVVGIAIGLGMPLLSVILETRGHSASMIGLNTAVAGLASIAGAPLATPLAMRFGVA
WTMIAMIATGALAFVGFHFAPNFWMWFPLRIVLHIALTVLFILSEFWISTSAPPHRRGLVLGIYATVLSLGFAAGPWLFA
HLGSSGFRPFGVIIALVTLAAIPVLAARNESPSIVADGETSNFLRYIWLVPTATFAVLVFGAVETGGFALFPVYGNRIGY
SEADAALLLTMIGLGNVLLQIPIGMISDRVSDRRYLLLACATVGLAGTLFMPFFAANWHLMAALLFVWGGVVAAMYTIGL
AHLGSQLSGHELASANAAFVLCYGVGMVLGPQAIGIGMDSFGPSGFGWSLGLFFGAYIALVCFRLVRKILL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787126, Length=265, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41419; Mature: 41288

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDTQPQGDERVHWLPMVAAISSISVVGIAIGLGMPLLSVILETRGHSASMIGLNTAVA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
GLASIAGAPLATPLAMRFGVAWTMIAMIATGALAFVGFHFAPNFWMWFPLRIVLHIALTV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LFILSEFWISTSAPPHRRGLVLGIYATVLSLGFAAGPWLFAHLGSSGFRPFGVIIALVTL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHH
AAIPVLAARNESPSIVADGETSNFLRYIWLVPTATFAVLVFGAVETGGFALFPVYGNRIG
HHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
YSEADAALLLTMIGLGNVLLQIPIGMISDRVSDRRYLLLACATVGLAGTLFMPFFAANWH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
LMAALLFVWGGVVAAMYTIGLAHLGSQLSGHELASANAAFVLCYGVGMVLGPQAIGIGMD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHEEHEEHHHHHHCCHHHCCCCC
SFGPSGFGWSLGLFFGAYIALVCFRLVRKILL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TVDTQPQGDERVHWLPMVAAISSISVVGIAIGLGMPLLSVILETRGHSASMIGLNTAVA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
GLASIAGAPLATPLAMRFGVAWTMIAMIATGALAFVGFHFAPNFWMWFPLRIVLHIALTV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LFILSEFWISTSAPPHRRGLVLGIYATVLSLGFAAGPWLFAHLGSSGFRPFGVIIALVTL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHH
AAIPVLAARNESPSIVADGETSNFLRYIWLVPTATFAVLVFGAVETGGFALFPVYGNRIG
HHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
YSEADAALLLTMIGLGNVLLQIPIGMISDRVSDRRYLLLACATVGLAGTLFMPFFAANWH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
LMAALLFVWGGVVAAMYTIGLAHLGSQLSGHELASANAAFVLCYGVGMVLGPQAIGIGMD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHEEHEEHHHHHHCCHHHCCCCC
SFGPSGFGWSLGLFFGAYIALVCFRLVRKILL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]