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The map label for this gene is hcaT [H]

Identifier: 13470961

GI number: 13470961

Start: 635286

End: 636551

Strand: Reverse

Name: hcaT [H]

Synonym: mll0804

Alternate gene names: 13470961

Gene position: 636551-635286 (Counterclockwise)

Preceding gene: 13470962

Following gene: 13470959

Centisome position: 9.05

GC content: 63.98

Gene sequence:

>1266_bases
ATGTCCCTCCCGCCGCTTTCGCCAGAACAGCTCGTCAAGCCGCGCCACTTCGAACTGCGCATGAGCCTGATCTTCGGCAC
ATTGTTCATCTCGCTCGGCACGCATCTGCCCTATTTCCCGCTGTGGCTGCAGGCCAAGGGGTTTCACGCCGAGCAGATCG
CCGTCATTCTGGCAGCGCCCATGTTCCTGCGCGTGGTGACAACGCCGCTGCTGACGACGCTCGCCGATCGGGCGAGGGAC
CGCGCCAATGTCTACGTCGCGCTGGTGGCAGCCTCCCTGCTGCTCTCGGCGGGCTATTTCCTCACCCCGACCTACGCGAT
GGTGCTGGCTGTGTCGCTGGGGCTGACCATTGTCTGGACGCCGCATTCGCCGATTGCCGATTCGCTGGCGCTTTCGGGCG
TGCGCCGCTTCGGCTCGAACTATGCAAGCATGCGCAAATGGGGATCGATCTGCTATCTCTGCGCCAATGTCGCGGGCGGC
TTCATCTTGGCGGCCACCGGTCCCCAGGCAGTGCCGGTGATCATAGTCCTTGCCCTTGCCGCGGCGCTCGTCGCCGGGCT
GCTGGCGCCGCGCATGGGCCGGCCGCGCAAGGCCTCGCCACTGTCGGCCGCGGAAATCCAGCACGCGGCGCCGAGCCTGT
TCAATGCCTATTTCCTCTACTTCACCTTTGGCGTCGGCATCATCACCGCCAGCCACGCCTTCCTTTACGGTTTCGTTTCC
ATCTACTGGAAATCGATCGGCATCAGCGATTCCGTCGTCGGCCTGCTGTGGGCCTGGGGCGTGGTGTCCGAAGTCTGCAT
GTTCCTGCTTTTCAACCGCATTTTCGCCTCCGTGTCGGTCGTCAAGGTGATGGTGATCGCCGGCATCGGCTCGATCGTGC
GCTGGATACTCTTTCCGCTGGTGTGGCCGCTCGGCCTTGGCATCGCCGGCTTCTTCGCCGTGCAGTCGCTGCATTCGGTG
TCTGTCGCCATGGTGCTCATCGGCCTGCAGAAAATGATCGCCGAGACAGTCTCCGAAGAGCGCACGGGGGCAGCGCAAGG
CATCGCCTATTTCTTCAACGGCTTCTTCATGGCCGCCGTTACGCTGGCTTCCGGCCCGCTCTATGACCGTCTCGGCGTCG
ATGGTTTCCTGGTGATGATCCCGATCGCGATCGTCGGCCTAGTGCTGATCGGACTTGCCGCGCGCTCAGCCCCAAAGCGC
CCGGTCGGGAGGGGAGACGAGCGAACCCTGGTAGACGAGGCCCGGCACACGGTCGCGGGCAAGTAG

Upstream 100 bases:

>100_bases
GGCAATCGATTGGTCCAGCCGGTTTCGCCAGGTTTTCTGCCATGTTAAGGGATCGATCCACGTCGCTAGCCAATTGAGCG
CGGCGTTATTGGATCGATTC

Downstream 100 bases:

>100_bases
CAACGGACCGTCAAGGTCGACGAAATCGGCGTCCTGGGCGAGCAGCACCGCCGGAGCCATGGCAAGCGAAGTGCCGACCA
TGCAGCCGACCATGATGCCA

Product: transporter of 3-phenylpropionic acid

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSLPPLSPEQLVKPRHFELRMSLIFGTLFISLGTHLPYFPLWLQAKGFHAEQIAVILAAPMFLRVVTTPLLTTLADRARD
RANVYVALVAASLLLSAGYFLTPTYAMVLAVSLGLTIVWTPHSPIADSLALSGVRRFGSNYASMRKWGSICYLCANVAGG
FILAATGPQAVPVIIVLALAAALVAGLLAPRMGRPRKASPLSAAEIQHAAPSLFNAYFLYFTFGVGIITASHAFLYGFVS
IYWKSIGISDSVVGLLWAWGVVSEVCMFLLFNRIFASVSVVKVMVIAGIGSIVRWILFPLVWPLGLGIAGFFAVQSLHSV
SVAMVLIGLQKMIAETVSEERTGAAQGIAYFFNGFFMAAVTLASGPLYDRLGVDGFLVMIPIAIVGLVLIGLAARSAPKR
PVGRGDERTLVDEARHTVAGK

Sequences:

>Translated_421_residues
MSLPPLSPEQLVKPRHFELRMSLIFGTLFISLGTHLPYFPLWLQAKGFHAEQIAVILAAPMFLRVVTTPLLTTLADRARD
RANVYVALVAASLLLSAGYFLTPTYAMVLAVSLGLTIVWTPHSPIADSLALSGVRRFGSNYASMRKWGSICYLCANVAGG
FILAATGPQAVPVIIVLALAAALVAGLLAPRMGRPRKASPLSAAEIQHAAPSLFNAYFLYFTFGVGIITASHAFLYGFVS
IYWKSIGISDSVVGLLWAWGVVSEVCMFLLFNRIFASVSVVKVMVIAGIGSIVRWILFPLVWPLGLGIAGFFAVQSLHSV
SVAMVLIGLQKMIAETVSEERTGAAQGIAYFFNGFFMAAVTLASGPLYDRLGVDGFLVMIPIAIVGLVLIGLAARSAPKR
PVGRGDERTLVDEARHTVAGK
>Mature_420_residues
SLPPLSPEQLVKPRHFELRMSLIFGTLFISLGTHLPYFPLWLQAKGFHAEQIAVILAAPMFLRVVTTPLLTTLADRARDR
ANVYVALVAASLLLSAGYFLTPTYAMVLAVSLGLTIVWTPHSPIADSLALSGVRRFGSNYASMRKWGSICYLCANVAGGF
ILAATGPQAVPVIIVLALAAALVAGLLAPRMGRPRKASPLSAAEIQHAAPSLFNAYFLYFTFGVGIITASHAFLYGFVSI
YWKSIGISDSVVGLLWAWGVVSEVCMFLLFNRIFASVSVVKVMVIAGIGSIVRWILFPLVWPLGLGIAGFFAVQSLHSVS
VAMVLIGLQKMIAETVSEERTGAAQGIAYFFNGFFMAAVTLASGPLYDRLGVDGFLVMIPIAIVGLVLIGLAARSAPKRP
VGRGDERTLVDEARHTVAGK

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=379, Percent_Identity=26.9129287598945, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 45113; Mature: 44982

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPPLSPEQLVKPRHFELRMSLIFGTLFISLGTHLPYFPLWLQAKGFHAEQIAVILAAP
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCHHHHHHHHHHH
MFLRVVTTPLLTTLADRARDRANVYVALVAASLLLSAGYFLTPTYAMVLAVSLGLTIVWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEC
PHSPIADSLALSGVRRFGSNYASMRKWGSICYLCANVAGGFILAATGPQAVPVIIVLALA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHH
AALVAGLLAPRMGRPRKASPLSAAEIQHAAPSLFNAYFLYFTFGVGIITASHAFLYGFVS
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYWKSIGISDSVVGLLWAWGVVSEVCMFLLFNRIFASVSVVKVMVIAGIGSIVRWILFPL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWPLGLGIAGFFAVQSLHSVSVAMVLIGLQKMIAETVSEERTGAAQGIAYFFNGFFMAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TLASGPLYDRLGVDGFLVMIPIAIVGLVLIGLAARSAPKRPVGRGDERTLVDEARHTVAG
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
SLPPLSPEQLVKPRHFELRMSLIFGTLFISLGTHLPYFPLWLQAKGFHAEQIAVILAAP
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEECCCCHHHHHHHHHHH
MFLRVVTTPLLTTLADRARDRANVYVALVAASLLLSAGYFLTPTYAMVLAVSLGLTIVWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCEEEEEC
PHSPIADSLALSGVRRFGSNYASMRKWGSICYLCANVAGGFILAATGPQAVPVIIVLALA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHH
AALVAGLLAPRMGRPRKASPLSAAEIQHAAPSLFNAYFLYFTFGVGIITASHAFLYGFVS
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYWKSIGISDSVVGLLWAWGVVSEVCMFLLFNRIFASVSVVKVMVIAGIGSIVRWILFPL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWPLGLGIAGFFAVQSLHSVSVAMVLIGLQKMIAETVSEERTGAAQGIAYFFNGFFMAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
TLASGPLYDRLGVDGFLVMIPIAIVGLVLIGLAARSAPKRPVGRGDERTLVDEARHTVAG
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]