Click here to switch to the map view.

The map label for this gene is trx

Identifier: 13358154

GI number: 13358154

Start: 737806

End: 738126

Strand: Reverse

Name: trx

Synonym: UU589

Alternate gene names: 13358154

Gene position: 738126-737806 (Counterclockwise)

Preceding gene: 13358155

Following gene: 13358153

Centisome position: 98.19

GC content: 23.99

Gene sequence:

>321_bases
ATGTTAATTAAATTAGAAAGTAACCAAAATTTAAATGAATTATTAAAGGAAAATCATTCTAAACCAATATTAATTGATTT
TTATGCGGATTGATGCCCTCCATGTCGTATGCTTATTCCAGTATTAGATTCAATTGAAAAAAAACATGGTGATGAATTTA
CTATTATTAAAATAAATGTTGATCATTTTCCAGAATTATCAACACAATATCAAGTCAAATCAATCCCTGCTTTATTTTAC
TTAAAAAATGGAGATATTAAAGCGACAAGTTTAGGATTTATTGATGAAAATTCTTTAGTTAATAAATTACGATCAATTTA
A

Upstream 100 bases:

>100_bases
GGTTATCCTGAATGTAATTTTATTCGTAATTTAGATGAATCAAACAATGATAAAAACGATTTTAATCAATAATAATATAA
TATTAAAAAGAGGAAAATTT

Downstream 100 bases:

>100_bases
TAATTTAAATTCATTAGTTTTAACTATTGCATTATTGCTTATTATTTAATATAATAAATAAGTTATATACATAAAGCAAT
AATTGTTTTGGAAACATACT

Product: thioredoxin

Products: NA

Alternate protein names: Trx-1; Thioredoxin-M [H]

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MLIKLESNQNLNELLKENHSKPILIDFYADWCPPCRMLIPVLDSIEKKHGDEFTIIKINVDHFPELSTQYQVKSIPALFY
LKNGDIKATSLGFIDENSLVNKLRSI

Sequences:

>Translated_106_residues
MLIKLESNQNLNELLKENHSKPILIDFYAD*CPPCRMLIPVLDSIEKKHGDEFTIIKINVDHFPELSTQYQVKSIPALFY
LKNGDIKATSLGFIDENSLVNKLRSI
>Mature_106_residues
MLIKLESNQNLNELLKENHSKPILIDFYAD*CPPCRMLIPVLDSIEKKHGDEFTIIKINVDHFPELSTQYQVKSIPALFY
LKNGDIKATSLGFIDENSLVNKLRSI

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=98, Percent_Identity=33.6734693877551, Blast_Score=74, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639826, Length=86, Percent_Identity=31.3953488372093, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12012; Mature: 12012

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKLESNQNLNELLKENHSKPILIDFYADCPPCRMLIPVLDSIEKKHGDEFTIIKINVD
CEEEECCCCCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
HFPELSTQYQVKSIPALFYLKNGDIKATSLGFIDENSLVNKLRSI
CCCCCCCCEEECCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MLIKLESNQNLNELLKENHSKPILIDFYADCPPCRMLIPVLDSIEKKHGDEFTIIKINVD
CEEEECCCCCHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
HFPELSTQYQVKSIPALFYLKNGDIKATSLGFIDENSLVNKLRSI
CCCCCCCCEEECCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2492995 [H]