Click here to switch to the map view.

The map label for this gene is rpe

Identifier: 13358019

GI number: 13358019

Start: 519367

End: 520026

Strand: Direct

Name: rpe

Synonym: UU456

Alternate gene names: 13358019

Gene position: 519367-520026 (Clockwise)

Preceding gene: 13358018

Following gene: 13358028

Centisome position: 69.09

GC content: 23.18

Gene sequence:

>660_bases
ATGAATAAGCAACTAGTTCCATCCCTTTTAGCATTTGATAAAAAATATCCTTATGAACAATTAAAGATCTTTAAAAAGCA
TCATCTTCAAACAATACATTATGATGTTATGGATCTAACATATGTTAATAACACTGCTTTTGAAACTGAACATTTAGAAT
GGCTACTAAAAAATGATTTTTTAGTACACATTCATCTAATGGTTATTAACCCTTTAGAAAAAATTAAACAATATTTTATA
TATAAACCAACTCGCATATCTTTTCATTTTGAAATGAATGATTATCAAACTAATTTATTAATCATTAATGAAATTAAAAA
ACATCATGTTTTAGCAGGGATTGCAATTCATCCTTGTTTATCACTAAACGATTATGCTTCTTATTTAAAAGAAGTTGATT
ATATTACTTTTATGTCGGTTATTCCAGGTAAGGGTGGACAAATTTTTTTAGAAGAAAGTTTATTAAAACTAAAAAAATTA
TATGAATATAAAATTAAAAATAATTTCAAATTTAAGATTGAAATTGATGGTGGTATTACTTTAGAAGTTATTAAAAAAAT
CAATATTCCAATTGATTTTTTTGTAAGCGGTTCTTATTTAGTGAAAAATATTGAAAAACTAGAGCAAACTGTTAACGAAT
TTAATCAACTTGTTAATTAA

Upstream 100 bases:

>100_bases
AAGCTTTTAGTCAAATTGAAAACGAACATAAAATTAAAGTTTACGATAAACGTTTAGCTAATAATAGTAATTTAAAAGGT
TGAATCATAAATAATCTATA

Downstream 100 bases:

>100_bases
TATTAATTCTTAATTAATTTTAGTAACTATTTTATTTAAAAACCATTTCTTATAGTAATTGAAATGTACTAATTAATAAA
AAAACACCACTGCAGGTGTT

Product: d-ribulose-5-phosphate 3 epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MNKQLVPSLLAFDKKYPYEQLKIFKKHHLQTIHYDVMDLTYVNNTAFETEHLEWLLKNDFLVHIHLMVINPLEKIKQYFI
YKPTRISFHFEMNDYQTNLLIINEIKKHHVLAGIAIHPCLSLNDYASYLKEVDYITFMSVIPGKGGQIFLEESLLKLKKL
YEYKIKNNFKFKIEIDGGITLEVIKKINIPIDFFVSGSYLVKNIEKLEQTVNEFNQLVN

Sequences:

>Translated_219_residues
MNKQLVPSLLAFDKKYPYEQLKIFKKHHLQTIHYDVMDLTYVNNTAFETEHLEWLLKNDFLVHIHLMVINPLEKIKQYFI
YKPTRISFHFEMNDYQTNLLIINEIKKHHVLAGIAIHPCLSLNDYASYLKEVDYITFMSVIPGKGGQIFLEESLLKLKKL
YEYKIKNNFKFKIEIDGGITLEVIKKINIPIDFFVSGSYLVKNIEKLEQTVNEFNQLVN
>Mature_219_residues
MNKQLVPSLLAFDKKYPYEQLKIFKKHHLQTIHYDVMDLTYVNNTAFETEHLEWLLKNDFLVHIHLMVINPLEKIKQYFI
YKPTRISFHFEMNDYQTNLLIINEIKKHHVLAGIAIHPCLSLNDYASYLKEVDYITFMSVIPGKGGQIFLEESLLKLKKL
YEYKIKNNFKFKIEIDGGITLEVIKKINIPIDFFVSGSYLVKNIEKLEQTVNEFNQLVN

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=177, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI219879828, Length=177, Percent_Identity=28.2485875706215, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1789788, Length=200, Percent_Identity=29.5, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790523, Length=199, Percent_Identity=28.643216080402, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17552948, Length=207, Percent_Identity=27.0531400966184, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24586301, Length=216, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25931; Mature: 25931

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQLVPSLLAFDKKYPYEQLKIFKKHHLQTIHYDVMDLTYVNNTAFETEHLEWLLKNDF
CCCCHHHHHHHHCCCCCHHHHHHHHHHCHHEEEEEEEEEEEECCCCCCHHHHHHHHCCCE
LVHIHLMVINPLEKIKQYFIYKPTRISFHFEMNDYQTNLLIINEIKKHHVLAGIAIHPCL
EEEEEEEEECHHHHHHHHHEECCCEEEEEEEECCCEEEEEEEEEHHHHHEEEEHHHCCCC
SLNDYASYLKEVDYITFMSVIPGKGGQIFLEESLLKLKKLYEYKIKNNFKFKIEIDGGIT
CHHHHHHHHHHHHHHHEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCE
LEVIKKINIPIDFFVSGSYLVKNIEKLEQTVNEFNQLVN
EEEHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKQLVPSLLAFDKKYPYEQLKIFKKHHLQTIHYDVMDLTYVNNTAFETEHLEWLLKNDF
CCCCHHHHHHHHCCCCCHHHHHHHHHHCHHEEEEEEEEEEEECCCCCCHHHHHHHHCCCE
LVHIHLMVINPLEKIKQYFIYKPTRISFHFEMNDYQTNLLIINEIKKHHVLAGIAIHPCL
EEEEEEEEECHHHHHHHHHEECCCEEEEEEEECCCEEEEEEEEEHHHHHEEEEHHHCCCC
SLNDYASYLKEVDYITFMSVIPGKGGQIFLEESLLKLKKLYEYKIKNNFKFKIEIDGGIT
CHHHHHHHHHHHHHHHEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCE
LEVIKKINIPIDFFVSGSYLVKNIEKLEQTVNEFNQLVN
EEEHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]