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The map label for this gene is fumA [C]

Identifier: 126698587

GI number: 126698587

Start: 1172153

End: 1172992

Strand: Direct

Name: fumA [C]

Synonym: CD1003

Alternate gene names: 126698587

Gene position: 1172153-1172992 (Clockwise)

Preceding gene: 126698586

Following gene: 126698588

Centisome position: 27.32

GC content: 32.86

Gene sequence:

>840_bases
TTGAGAAAAATAAAATCTGAACAAATCGTCGAGCAGGTAAAAAAACTTTGTATAGAAGCGAGCCTATATTTAGGAGAAGA
TGTTTTAAGTTGTATAAAAGAAAAAGCGAAAAGCGAAAAGAGTGAAGTTGGAAAAAATATATTGAATATATTAGTTGAAA
ATGCTGAAATAGCTAAAGAAAAAAATATACCAATATGCCAAGATACTGGTATGGCTGTATTTTTTGTTGAAATAGGACAA
GAAGTTTTAATTGAAGGAGACACACTTACTGATGCTATAAATGAGGGAGTAAGACAAGGGTATGAAGAAGGCTACTTAAG
AAAATCTGTTGTAAGTCCAATTAACAGAGTAAATACAAAAGATAATACACCTGCTGTTATTCATTATGATATGGTAAAAG
GTGATAAAATTAAAATAGAATTTGCAGCTAAGGGATTTGGAAGCGAAAATATGAGTAAGATGAAAATGTTAAAGCCATCA
GATGGATTGGAAGGAATTAAAAAATTCATAATAGATACAGTTTCAGAAGCTGGACCTAACCCATGCCCTCCTATGGTAAT
TGGAGTTGGTATAGGTGGGACTGTGGACAAATGTGCTCAAATAGCTAAAAAGGCACTTTTTAGAGAACTAGGTGAATTTA
ATAAGGACGAAAATATAGCAAAACTTGAAAGTGAACTATTAACAGCTATTAATAAACTTGGTATAGGACCTCAAGGCTTA
GGTGGTACTACAACAGCTTTGGGATTAAACATAGAGACTTTTCCTACACACATAGCAGGTCTACCTGTTGTTGTAAATAT
AAACTGCCATGCATCAAGACATAAGAAGGTAGTAATTTAG

Upstream 100 bases:

>100_bases
ATGTGTAATTGGTATAAAAATATTGAGAAATTTTAAAAACAATGGTAAAGTGTAAGTATAATCACGAATATTTTTTATAA
AGTAATGGAGGGATGTTCGC

Downstream 100 bases:

>100_bases
GAGGAAAATAAAATGATAAAAATAACTACACCTGTAAATGAAATTGATATAGCAAAATTAAATTGTGGAGATACAATTAG
TTTGAGTGGTATACTTTATA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVGKNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQ
EVLIEGDTLTDAINEGVRQGYEEGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDENIAKLESELLTAINKLGIGPQGL
GGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKKVVI

Sequences:

>Translated_279_residues
MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVGKNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQ
EVLIEGDTLTDAINEGVRQGYEEGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDENIAKLESELLTAINKLGIGPQGL
GGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKKVVI
>Mature_279_residues
MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVGKNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQ
EVLIEGDTLTDAINEGVRQGYEEGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDENIAKLESELLTAINKLGIGPQGL
GGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKKVVI

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=276, Percent_Identity=32.2463768115942, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790564, Length=257, Percent_Identity=32.6848249027237, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787897, Length=257, Percent_Identity=32.295719844358, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30278; Mature: 30278

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVGKNILNILVENAEIAKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYEEGYLRKSVVSPINRVNTK
CCCCCCCCCCCEEEEEECCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPSDGLEGIKKFIIDTVSEAGPN
CCCCEEEEEEEECCCEEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDENIAKLESELLTAINKLGIGPQGL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKKVVI
CCCCCEEECCCHHHHHHHCCCCEEEEEECCCCCCCEECC
>Mature Secondary Structure
MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVGKNILNILVENAEIAKE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYEEGYLRKSVVSPINRVNTK
CCCCCCCCCCCEEEEEECCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPSDGLEGIKKFIIDTVSEAGPN
CCCCEEEEEEEECCCEEEEEEEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
PCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDENIAKLESELLTAINKLGIGPQGL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
GGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKKVVI
CCCCCEEECCCHHHHHHHCCCCEEEEEECCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]