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The map label for this gene is argD [H]

Identifier: 126696825

GI number: 126696825

Start: 1255658

End: 1256911

Strand: Direct

Name: argD [H]

Synonym: P9301_14871

Alternate gene names: 126696825

Gene position: 1255658-1256911 (Clockwise)

Preceding gene: 126696823

Following gene: 126696826

Centisome position: 76.48

GC content: 34.93

Gene sequence:

>1254_bases
GTGGAATTGGTAGACGCACCGCACTCAAAATGCGGCACCTTCGGGTATGTCGGTTCAAGTCCGACCGCTCCCACTTTGAT
GAATACATATAGTAGATTCGATATATCTTTCAAAAAAGGAAAAGGTTGTTGGCTATGGGACAAAACAGGTAAAAAATATC
TTGATGCAGTCGCTGGTATAGCAACTTGTAGTCTTGGCCATAGCGATAGAGTTTTAAGAAGAAGGCTATCAACTCAACTA
AGAAAGATTCAGCACATTTCCAATCTCTACAACATTGAAGAACAAGAACAATTAAGCAGAACTTTAACAAATATAAGTTG
CGCCAAAAGTGTCTTCTTCTGCAACAGTGGTGCGGAAGCAAATGAATCAGCAATTAAATTAATTAAAAAATATGGTAATA
CAATAAATAAGGGTAAAGAATCGATTATTCTCGCTGCAGAATCCAGCTTTCATGGAAGGACGCTGGCAGCATTGAGTGCT
ACTGGACAGCCCAAATATCAAAAAGGCTTCGAACCATTGATTCAAGGGTTCAAATTTTTTAAATTTAACAATTTTGATTC
GGTAAAAAAATTATTTGAAGAGTGTGAAAATAATAATCAAAAAATTTCAGGCGTTTTAGTTGAACCAATACAAGGTGAAG
GTGGCGTAATTCCTGGAAGCAAAATATTTTTTAAAAGTCTGAGAAATATATGTGATGAATATAATTCTCTCCTAATTTTA
GATGAGGTTCAAAGTGGAGTAGGTCGAACTGGGAAAATGTGGGGTTATGAGAATTTAGGCATTGAACCTGATGGATTCAC
CCTTGCTAAAGGATTAGGAGGAGGTCATGCAATTGGAGCATTATTAGTAAAAGAAAAAGCCAATATTTTTTATCCAGGAG
ATCATGCAAGTACATTTGGGGGTAACCCTTTCGCCTGTAAAGCTGCCCTAACTGTATTAGAAGAAATAAATAGAAGAAAT
CTTATCAATAATGTTTATCTAAGGGGGGAACAATTAAGTGCTGGATTTGAAGAATTATCAAAAAAATTTCCAAATATTAT
TACCGGTAAAAGAGGTTTAGGTTTAATACAAGGTCTTGTAATCAATAAAGATTATGTTGATGCAAAAAAAATTACATTAA
AAGCTTTTGATAAAGGGTTACTGGTGGTTCCGGCAGGAGGAAATGTTGTAAGGATTGTCCCACCATTAGTTATATCTCGA
AGAGAAATTAATATTCTTTTGGATAAGCTAAATTTAATTTTTGGAGAGTTATAG

Upstream 100 bases:

>100_bases
AGCGTTATCTTGATAACTGTTCATTGGCAAAAACAATAGTCAATGAGTTGATTTTTGTTATAATAAAAAAGTTCATTTTT
GCAAAAGCCTTGGGAGCGTG

Downstream 100 bases:

>100_bases
CAATTTAAATTTTGAAAAATGCAAATTTAAAAACTTTTGAATTATTATCACCTAAATATGAAAGGGATAATATCAATTTA
GGCTTATCAAGAATTAAAAA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKTGKKYLDAVAGIATCSLGHSDRVLRRRLSTQL
RKIQHISNLYNIEEQEQLSRTLTNISCAKSVFFCNSGAEANESAIKLIKKYGNTINKGKESIILAAESSFHGRTLAALSA
TGQPKYQKGFEPLIQGFKFFKFNNFDSVKKLFEECENNNQKISGVLVEPIQGEGGVIPGSKIFFKSLRNICDEYNSLLIL
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFYPGDHASTFGGNPFACKAALTVLEEINRRN
LINNVYLRGEQLSAGFEELSKKFPNIITGKRGLGLIQGLVINKDYVDAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISR
REINILLDKLNLIFGEL

Sequences:

>Translated_417_residues
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKTGKKYLDAVAGIATCSLGHSDRVLRRRLSTQL
RKIQHISNLYNIEEQEQLSRTLTNISCAKSVFFCNSGAEANESAIKLIKKYGNTINKGKESIILAAESSFHGRTLAALSA
TGQPKYQKGFEPLIQGFKFFKFNNFDSVKKLFEECENNNQKISGVLVEPIQGEGGVIPGSKIFFKSLRNICDEYNSLLIL
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFYPGDHASTFGGNPFACKAALTVLEEINRRN
LINNVYLRGEQLSAGFEELSKKFPNIITGKRGLGLIQGLVINKDYVDAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISR
REINILLDKLNLIFGEL
>Mature_417_residues
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKTGKKYLDAVAGIATCSLGHSDRVLRRRLSTQL
RKIQHISNLYNIEEQEQLSRTLTNISCAKSVFFCNSGAEANESAIKLIKKYGNTINKGKESIILAAESSFHGRTLAALSA
TGQPKYQKGFEPLIQGFKFFKFNNFDSVKKLFEECENNNQKISGVLVEPIQGEGGVIPGSKIFFKSLRNICDEYNSLLIL
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFYPGDHASTFGGNPFACKAALTVLEEINRRN
LINNVYLRGEQLSAGFEELSKKFPNIITGKRGLGLIQGLVINKDYVDAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISR
REINILLDKLNLIFGEL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=391, Percent_Identity=32.4808184143223, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI284507298, Length=304, Percent_Identity=35.5263157894737, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI13994255, Length=430, Percent_Identity=26.046511627907, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=26.7942583732057, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=26.9879518072289, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442709, Length=355, Percent_Identity=28.169014084507, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI188536080, Length=440, Percent_Identity=24.7727272727273, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI38679950, Length=440, Percent_Identity=24.7727272727273, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI38679946, Length=440, Percent_Identity=24.7727272727273, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=21.7703349282297, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1788044, Length=374, Percent_Identity=42.2459893048128, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI1789759, Length=382, Percent_Identity=35.8638743455497, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI145693181, Length=384, Percent_Identity=34.1145833333333, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=30.7692307692308, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=29.97542997543, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786349, Length=318, Percent_Identity=27.9874213836478, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1786991, Length=402, Percent_Identity=26.1194029850746, Blast_Score=99, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=385, Percent_Identity=33.5064935064935, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI25144274, Length=274, Percent_Identity=36.4963503649635, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=29.2237442922374, Blast_Score=161, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=403, Percent_Identity=27.0471464019851, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=433, Percent_Identity=27.4826789838337, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71981843, Length=166, Percent_Identity=29.5180722891566, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=395, Percent_Identity=39.2405063291139, Blast_Score=248, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=394, Percent_Identity=31.4720812182741, Blast_Score=200, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6321456, Length=433, Percent_Identity=27.0207852193995, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=457, Percent_Identity=24.2888402625821, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=32.7272727272727, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28574759, Length=440, Percent_Identity=28.4090909090909, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI161085790, Length=438, Percent_Identity=27.8538812785388, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281366494, Length=438, Percent_Identity=28.310502283105, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24667139, Length=438, Percent_Identity=28.310502283105, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24667143, Length=438, Percent_Identity=28.310502283105, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356575, Length=415, Percent_Identity=26.5060240963855, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45766; Mature: 45766

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKTGKKYLDAVAGI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCEEEECCCCHHHHHHHHHH
ATCSLGHSDRVLRRRLSTQLRKIQHISNLYNIEEQEQLSRTLTNISCAKSVFFCNSGAEA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCC
NESAIKLIKKYGNTINKGKESIILAAESSFHGRTLAALSATGQPKYQKGFEPLIQGFKFF
CHHHHHHHHHHCCHHCCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHE
KFNNFDSVKKLFEECENNNQKISGVLVEPIQGEGGVIPGSKIFFKSLRNICDEYNSLLIL
ECCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEE
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFYPGDHASTFG
EHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHEECCCCEEECCCCCCCCC
GNPFACKAALTVLEEINRRNLINNVYLRGEQLSAGFEELSKKFPNIITGKRGLGLIQGLV
CCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHCCHHHHHHHCCCHHCCCCCHHHHHHEE
INKDYVDAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISRREINILLDKLNLIFGEL
ECCCCCCHHHEEEEECCCCEEEEECCCCEEEECCCHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELVDAPHSKCGTFGYVGSSPTAPTLMNTYSRFDISFKKGKGCWLWDKTGKKYLDAVAGI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCEEEECCCCHHHHHHHHHH
ATCSLGHSDRVLRRRLSTQLRKIQHISNLYNIEEQEQLSRTLTNISCAKSVFFCNSGAEA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCC
NESAIKLIKKYGNTINKGKESIILAAESSFHGRTLAALSATGQPKYQKGFEPLIQGFKFF
CHHHHHHHHHHCCHHCCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHE
KFNNFDSVKKLFEECENNNQKISGVLVEPIQGEGGVIPGSKIFFKSLRNICDEYNSLLIL
ECCCHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCEEEE
DEVQSGVGRTGKMWGYENLGIEPDGFTLAKGLGGGHAIGALLVKEKANIFYPGDHASTFG
EHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHEECCCCEEECCCCCCCCC
GNPFACKAALTVLEEINRRNLINNVYLRGEQLSAGFEELSKKFPNIITGKRGLGLIQGLV
CCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHCCHHHHHHHCCCHHCCCCCHHHHHHEE
INKDYVDAKKITLKAFDKGLLVVPAGGNVVRIVPPLVISRREINILLDKLNLIFGEL
ECCCCCCHHHEEEEECCCCEEEEECCCCEEEECCCHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]