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The map label for this gene is murA

Identifier: 126696823

GI number: 126696823

Start: 1253753

End: 1255123

Strand: Direct

Name: murA

Synonym: P9301_14851

Alternate gene names: 126696823

Gene position: 1253753-1255123 (Clockwise)

Preceding gene: 126696818

Following gene: 126696825

Centisome position: 76.36

GC content: 34.14

Gene sequence:

>1371_bases
ATGATTTGCGGTAGCAAAAATAAGTCATATCTTAAATCACAAAATTTAAAGATTTTTGGCCAAGGCAAATTAAATGGAAT
CGTTGAAATAAGTGGTGCGAAGAATTCGGCCTTAGTTTTACTTGCTGCATCATTACTAACTAATGAAAGAATAGTTCTTC
AGAATGTTCCTCGCCTCACTGACATTGAAAAAATGGCTAATATCCTTAGAAATTTAGGGGTTAAAATAGTAGAAAAAAAC
AATAGATTAGAGTTAGATTCACAAAATATTTCTATTAAAGAACTTCCATATGAACTTGTTAATGGACTAAGAGCAAGTTT
CTTTTGTATCGGTCCACTATTAAGTAAATTTGGAGAAGCTAAAGTCCCTTTGCCTGGAGGGTGCAATATTGGTTCAAGGC
CAATAGATGAGCACATTAATGGGCTTAAAGCACTAGGAGCGGAAATTCTTATTGAAGAAGAAATTGTCAAAGCAAATATA
AAAGGAGATAAAAGCAGATTAATTGGTACCCATATCAAATTAAAGTGCCCAAGCGTAGGAGCTACTGAAACTTTAATAAT
GGCCGCATCATTAGCAGAGGGAAGAACTACGATTGAGAATGCTGCAAGAGAACCTGAAATTCAGGATCTATGCCAAATGC
TAAATAAAATGGGGGCAAAAATTTACGACTCTGGCAAAGAAAAAATAATTATTGATGGTGTTAATGAGCTGTGTGGTTGT
AGTCATAAAGTAATTCCAGATCGAATAGAGGCTGGCACTTTTTTAATAGCTGCTGCTGCGACTTCCTCTTCGATAACAAT
ATCTCCTGTAATTCCTAATCATCTTGAAGCTGTCACGAATAAGCTTCAAGAGAGCGGAAGTAAAATTACGATTAAAGGTA
ATTCAATTACAATCAACTGTAATAAGATCAAAGGGGTAGATATTGAAACAGCTCCTTTTCCAGGATTTCCAACTGATTTG
CAAGCACCATTTACAACTTTAATGGCAATCGCAAATGGTGAATCAAAGATAACAGAAACAATTTTCGAAAATAGAATGAA
CCATGTTCATTTACTTAACAAAATGGGGGCGAATATAAAATTAAACAAAAACATAGCTCACATCAAAGGTGTTAAAAAAT
TTAAGGGGATGGATCTAGTTGGATCTGATTTGAGGACTTCAGCTGCATTAATAATTGCTGGGATTATAGCTGAAGGAACT
AGTACAATTTCTGGTTTAGAGCATTTGGATAGAGGTTATGAAAATTTTGAATCAAAACTAAAAATATTGGGTATAAAAAT
TACCAGAGAGTTTAACAAAAAAACTTTGAAAAATAAGGAATTTAAGACGAGTTCAGACCCAGCAGATATTCCTCGATATA
AAGCAGCCTAA

Upstream 100 bases:

>100_bases
AAAAAAATATATTTTCACTTTTAATTAATATTCAAGACGTTACATAGGGTGGACTTACTAATTTTCGTTTGTCATCATGA
ATCTAATAAATTAAGTCTTA

Downstream 100 bases:

>100_bases
ATTACAAAAAGCTTGAAAACTATATAAATGTTTAAACGTAAGCAATATTAATGAGTGAAATGCAGCCTAAAAATATGATA
AACAACACTAAAAAGCGACT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MICGSKNKSYLKSQNLKIFGQGKLNGIVEISGAKNSALVLLAASLLTNERIVLQNVPRLTDIEKMANILRNLGVKIVEKN
NRLELDSQNISIKELPYELVNGLRASFFCIGPLLSKFGEAKVPLPGGCNIGSRPIDEHINGLKALGAEILIEEEIVKANI
KGDKSRLIGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCQMLNKMGAKIYDSGKEKIIIDGVNELCGC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVTNKLQESGSKITIKGNSITINCNKIKGVDIETAPFPGFPTDL
QAPFTTLMAIANGESKITETIFENRMNHVHLLNKMGANIKLNKNIAHIKGVKKFKGMDLVGSDLRTSAALIIAGIIAEGT
STISGLEHLDRGYENFESKLKILGIKITREFNKKTLKNKEFKTSSDPADIPRYKAA

Sequences:

>Translated_456_residues
MICGSKNKSYLKSQNLKIFGQGKLNGIVEISGAKNSALVLLAASLLTNERIVLQNVPRLTDIEKMANILRNLGVKIVEKN
NRLELDSQNISIKELPYELVNGLRASFFCIGPLLSKFGEAKVPLPGGCNIGSRPIDEHINGLKALGAEILIEEEIVKANI
KGDKSRLIGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCQMLNKMGAKIYDSGKEKIIIDGVNELCGC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVTNKLQESGSKITIKGNSITINCNKIKGVDIETAPFPGFPTDL
QAPFTTLMAIANGESKITETIFENRMNHVHLLNKMGANIKLNKNIAHIKGVKKFKGMDLVGSDLRTSAALIIAGIIAEGT
STISGLEHLDRGYENFESKLKILGIKITREFNKKTLKNKEFKTSSDPADIPRYKAA
>Mature_456_residues
MICGSKNKSYLKSQNLKIFGQGKLNGIVEISGAKNSALVLLAASLLTNERIVLQNVPRLTDIEKMANILRNLGVKIVEKN
NRLELDSQNISIKELPYELVNGLRASFFCIGPLLSKFGEAKVPLPGGCNIGSRPIDEHINGLKALGAEILIEEEIVKANI
KGDKSRLIGTHIKLKCPSVGATETLIMAASLAEGRTTIENAAREPEIQDLCQMLNKMGAKIYDSGKEKIIIDGVNELCGC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVTNKLQESGSKITIKGNSITINCNKIKGVDIETAPFPGFPTDL
QAPFTTLMAIANGESKITETIFENRMNHVHLLNKMGANIKLNKNIAHIKGVKKFKGMDLVGSDLRTSAALIIAGIIAEGT
STISGLEHLDRGYENFESKLKILGIKITREFNKKTLKNKEFKTSSDPADIPRYKAA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=416, Percent_Identity=46.875, Blast_Score=380, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_PROM0 (A3PED3)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091709.1
- ProteinModelPortal:   A3PED3
- SMR:   A3PED3
- STRING:   A3PED3
- GeneID:   4911941
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_14851
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   NRFMHLE
- ProtClustDB:   PRK09369
- BioCyc:   PMAR167546:P9301ORF_1509-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 49387; Mature: 49387

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICGSKNKSYLKSQNLKIFGQGKLNGIVEISGAKNSALVLLAASLLTNERIVLQNVPRLT
CCCCCCCCHHHHCCCEEEEECCCCCEEEEECCCCCCCHHEEEHHHHCCCEEEECCCCCCC
DIEKMANILRNLGVKIVEKNNRLELDSQNISIKELPYELVNGLRASFFCIGPLLSKFGEA
CHHHHHHHHHHCCEEEEECCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
KVPLPGGCNIGSRPIDEHINGLKALGAEILIEEEIVKANIKGDKSRLIGTHIKLKCPSVG
CCCCCCCCCCCCCCHHHHHHHHHHHCHHHEEHHHHHHCCCCCCCHHEEEEEEEEECCCCC
ATETLIMAASLAEGRTTIENAAREPEIQDLCQMLNKMGAKIYDSGKEKIIIDGVNELCGC
CHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVTNKLQESGSKITIKGNSITINC
CCCCCCCHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEE
NKIKGVDIETAPFPGFPTDLQAPFTTLMAIANGESKITETIFENRMNHVHLLNKMGANIK
CEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCEE
LNKNIAHIKGVKKFKGMDLVGSDLRTSAALIIAGIIAEGTSTISGLEHLDRGYENFESKL
ECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCE
KILGIKITREFNKKTLKNKEFKTSSDPADIPRYKAA
EEEEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MICGSKNKSYLKSQNLKIFGQGKLNGIVEISGAKNSALVLLAASLLTNERIVLQNVPRLT
CCCCCCCCHHHHCCCEEEEECCCCCEEEEECCCCCCCHHEEEHHHHCCCEEEECCCCCCC
DIEKMANILRNLGVKIVEKNNRLELDSQNISIKELPYELVNGLRASFFCIGPLLSKFGEA
CHHHHHHHHHHCCEEEEECCCCEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
KVPLPGGCNIGSRPIDEHINGLKALGAEILIEEEIVKANIKGDKSRLIGTHIKLKCPSVG
CCCCCCCCCCCCCCHHHHHHHHHHHCHHHEEHHHHHHCCCCCCCHHEEEEEEEEECCCCC
ATETLIMAASLAEGRTTIENAAREPEIQDLCQMLNKMGAKIYDSGKEKIIIDGVNELCGC
CHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCEEEEECCHHHCCC
SHKVIPDRIEAGTFLIAAAATSSSITISPVIPNHLEAVTNKLQESGSKITIKGNSITINC
CCCCCCCHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEECCEEEEEE
NKIKGVDIETAPFPGFPTDLQAPFTTLMAIANGESKITETIFENRMNHVHLLNKMGANIK
CEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCEE
LNKNIAHIKGVKKFKGMDLVGSDLRTSAALIIAGIIAEGTSTISGLEHLDRGYENFESKL
ECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCE
KILGIKITREFNKKTLKNKEFKTSSDPADIPRYKAA
EEEEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA