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The map label for this gene is ffh [H]

Identifier: 126696809

GI number: 126696809

Start: 1237922

End: 1239400

Strand: Reverse

Name: ffh [H]

Synonym: P9301_14711

Alternate gene names: 126696809

Gene position: 1239400-1237922 (Counterclockwise)

Preceding gene: 126696810

Following gene: 126696808

Centisome position: 75.49

GC content: 36.17

Gene sequence:

>1479_bases
ATGTTTGATGAACTCTCGTCACGCTTTGAAGACGCAGTAAAGGGTTTAAGAGGCGAAGCAAAAATTAGTGAAAATAATAT
TAACGATGCCTTGAAGGAGGTAAAAAGAGCACTCCTTGATGCAGATGTAAGTTTGTCCGTAGTTAAAGAGTTTATAACAG
ATGTTAAAGATAAAGCTATTGGAGAAGAAGTAGTTAGAGGTGTAAACCCTGGTCAAAAATTTATAGAAGTTGTAAATAAA
GAATTGATTAAAATTATGGGGAATGAAAATTCTCCATTAAACGAAAATGAAAATAGTCCTACAGTCATTTTGATGGCTGG
ACTTCAGGGAGCGGGTAAAACAACTGCAACAGGAAAATTAGGACTTTATTTAAAGGAAAAAGATAAAAAAGTTCTTTTGG
TTGCTGCAGATATTTATCGACCAGCTGCTGTAGAGCAGCTTAAAACATTGGGAAGTCAATATGAATTAGAAGTTTTTTCA
GCTAAAGAAAAAAATAGCAAACCAGAAGAAATAGCAAAGGAAGCATTGAATTTTGCTAACGAAAATGATTTTAATTCGAT
AATTATTGATACCGCAGGAAGACTACAAATTGATGATTCCATGATGAGTGAAATGGTTCGAATAAAAGAAGTTTCTAATC
CTGATGAGGTTTTGCTTGTTGTTGATTCAATGATTGGGCAAGAAGCTGCAGACTTAACAAAGTCATTTCATGAAAAAGTA
GGAATCACAGGGGCGATATTAACTAAGTTGGATGGTGACTCAAGAGGCGGAGCTGCTTTATCAATAAGAAAAATAAGTGG
TAAACCAATCAAATTTATAGGTGTAGGTGAAAAAATAGAAGCTCTTCAACCATTTCATCCAGAGAGAATGGCTAGCAGAA
TTTTAGGGATGGGCGATGTATTGACACTTGTTGAAAAAGCACAAAAAGAAGTTGAACTTGCTGATGCAGAAGCGATGCAA
AAGAAACTTCAAGAAGCGACTTTCGACTTTAATGATTTTGTAAAGCAAATGAGATTAATTAAAAGAATGGGTTCACTTGG
TGGATTGATTAAATTGATTCCTGGAATGAATAAAATAGATGATGGGATGATAAAAGATGGAGAAGATCAACTTAAGAAAA
TAGAATCTATGATCTCGTCAATGACTCTTGAGGAGAAACAAAAACCCGAAGTTCTTGCCGCTCAACCTTCAAGAAGACAA
AGGATCGCCCAAGGTAGCGGCTATGAAGCAAAGGATGTAGATAAAGTATTAGCTGATTTTCAAAGAATGAGAGGTTTTAT
GAAACAAATGTCTAATGGAGGAATGCCAGGAATGGGAGGAATGCCAGGAATGGGAGGAATGCCAGGAATGGGAGGAATGC
CAGGAATGGGAGGAATGCCAGGAATGGGAGGAATGCCAGGAATGGGAGGTGTGAGTGGTAACAAGCCAATGAAAAAACAA
AAAAATAATAAAAAGAAAAAAGGTTTTGCCGATTTATAG

Upstream 100 bases:

>100_bases
TAGGGTTTTCAAATAAATCATGGAAATTGGTTGATTTCGTGAGCGGCTTGTAATTACAAACTTCAAGATCATCTATAATA
ATTAAAATTACTTTTTAATA

Downstream 100 bases:

>100_bases
TTTCTATATTTTTACCTTTAAATGATATTATTATAAAAAATGCATTAATTTAAGATGATTAAATTGCGCCTTAAGCGCTT
TGGAAAGAAAAAAGAGGCAA

Product: signal recognition particle protein (SRP54)

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFITDVKDKAIGEEVVRGVNPGQKFIEVVNK
ELIKIMGNENSPLNENENSPTVILMAGLQGAGKTTATGKLGLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYELEVFS
AKEKNSKPEEIAKEALNFANENDFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
GITGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEAMQ
KKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKIDDGMIKDGEDQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYEAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGVSGNKPMKKQ
KNNKKKKGFADL

Sequences:

>Translated_492_residues
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFITDVKDKAIGEEVVRGVNPGQKFIEVVNK
ELIKIMGNENSPLNENENSPTVILMAGLQGAGKTTATGKLGLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYELEVFS
AKEKNSKPEEIAKEALNFANENDFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
GITGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEAMQ
KKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKIDDGMIKDGEDQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYEAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGVSGNKPMKKQ
KNNKKKKGFADL
>Mature_492_residues
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFITDVKDKAIGEEVVRGVNPGQKFIEVVNK
ELIKIMGNENSPLNENENSPTVILMAGLQGAGKTTATGKLGLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYELEVFS
AKEKNSKPEEIAKEALNFANENDFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
GITGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDVLTLVEKAQKEVELADAEAMQ
KKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKIDDGMIKDGEDQLKKIESMISSMTLEEKQKPEVLAAQPSRRQ
RIAQGSGYEAKDVDKVLADFQRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGVSGNKPMKKQ
KNNKKKKGFADL

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=443, Percent_Identity=35.2144469525959, Blast_Score=251, Evalue=8e-67,
Organism=Homo sapiens, GI226371618, Length=385, Percent_Identity=35.3246753246753, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=41.5094339622642, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI295424842, Length=315, Percent_Identity=25.7142857142857, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI23308697, Length=315, Percent_Identity=25.7142857142857, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1788963, Length=427, Percent_Identity=48.9461358313817, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=36.6533864541833, Blast_Score=156, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17539958, Length=432, Percent_Identity=29.8611111111111, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI193206261, Length=299, Percent_Identity=29.7658862876254, Blast_Score=124, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325345, Length=477, Percent_Identity=33.1236897274633, Blast_Score=250, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6320498, Length=325, Percent_Identity=23.6923076923077, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17647949, Length=442, Percent_Identity=31.2217194570136, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24641198, Length=303, Percent_Identity=27.3927392739274, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53423; Mature: 53423

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFITDVKDKAI
CCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEEVVRGVNPGQKFIEVVNKELIKIMGNENSPLNENENSPTVILMAGLQGAGKTTATGKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
GLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYELEVFSAKEKNSKPEEIAKEALNFAN
EEEEECCCCEEEEEEHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCC
ENDFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
CCCCCEEEEECCCCEEECHHHHHHHHHHHHCCCCCCEEEHHHHHHCHHHHHHHHHHHHHH
GITGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDV
CCCHHHHEECCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHH
LTLVEKAQKEVELADAEAMQKKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
DGMIKDGEDQLKKIESMISSMTLEEKQKPEVLAAQPSRRQRIAQGSGYEAKDVDKVLADF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHH
QRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGVSGNKPMKKQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KNNKKKKGFADL
HCCCCCCCCCCC
>Mature Secondary Structure
MFDELSSRFEDAVKGLRGEAKISENNINDALKEVKRALLDADVSLSVVKEFITDVKDKAI
CCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEEVVRGVNPGQKFIEVVNKELIKIMGNENSPLNENENSPTVILMAGLQGAGKTTATGKL
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCE
GLYLKEKDKKVLLVAADIYRPAAVEQLKTLGSQYELEVFSAKEKNSKPEEIAKEALNFAN
EEEEECCCCEEEEEEHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCC
ENDFNSIIIDTAGRLQIDDSMMSEMVRIKEVSNPDEVLLVVDSMIGQEAADLTKSFHEKV
CCCCCEEEEECCCCEEECHHHHHHHHHHHHCCCCCCEEEHHHHHHCHHHHHHHHHHHHHH
GITGAILTKLDGDSRGGAALSIRKISGKPIKFIGVGEKIEALQPFHPERMASRILGMGDV
CCCHHHHEECCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHH
LTLVEKAQKEVELADAEAMQKKLQEATFDFNDFVKQMRLIKRMGSLGGLIKLIPGMNKID
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
DGMIKDGEDQLKKIESMISSMTLEEKQKPEVLAAQPSRRQRIAQGSGYEAKDVDKVLADF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHH
QRMRGFMKQMSNGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGMPGMGGVSGNKPMKKQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
KNNKKKKGFADL
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]