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The map label for this gene is galE [H]

Identifier: 126696753

GI number: 126696753

Start: 1181603

End: 1182595

Strand: Reverse

Name: galE [H]

Synonym: P9301_14151

Alternate gene names: 126696753

Gene position: 1182595-1181603 (Counterclockwise)

Preceding gene: 126696754

Following gene: 126696752

Centisome position: 72.03

GC content: 31.32

Gene sequence:

>993_bases
ATGCATTGTAAAAGAATTGTTGTAACTGGAGGTGCAGGATATATAGGCTCTCATTTTTGCAAGACAGCATTTTTAAAAGG
GCATAAAACTTTTGTAATTGATAATTTAATTACAGGCAATTATGATTTTATAAAATGGGGAGAATTCTACAAATTAGATA
TAAGAGAAGAGAGCTCTTTTAAGGAGTTATTGTTAAAAATTAAACCAGATTATTTAGTTCATTTTGCCGCTTCTGCTTAT
GTAAGTGAATCAATATTTAAACCTCTTGATTATATTTCTAATAATATTGATGGAATGAGATCAGTTTGTAAGATATGCTC
AGAAATTAAAATACCTATTGTATTCTCCTCTTCTTGTTCAGTATATGGTGAAGCAAAAAATGTTCCAATTAATGAGTCAG
AACCACTTAATCCTTTAAGTCCTTATGGTGAAACAAAACTATTTTGCGAGAAAATATTGAAGTGGTGCTCAAATGCTTAT
GGTTTGCGATGGGTATCTCTAAGGTATTTCAATGCCGCAGGAGCGGATGAAGACCTTGAAATAGGTGAAAAACATGATCC
TGAAACACATATAATTCCCTTGGCTATAAGGGCCTTAGGTGATTCTGGCGAAACGCTAAAAATATTCGGAAGAGATTATG
ATACTTTTGATGGAACAGCTGTAAGAGATTTTATTCATGTTATGGATTTGGCTTCTGCCCACTTAAAAGCAATAGAATAT
TTAGCTGAAGGTGGAATGTCAAACATTTTTAATTTAGGAAGTGGTAATGGAACAAGTATTAAATCAATTATTAATGGATT
AGAGAATATTTCATCAAAGCAGGTCAAATTAAAATACTGTGAAAGAAGAGAGGAAGACCCATCCTGTTTATTTGCTGATA
TATCTAAAGCAAAAAGTATTTTGAATTGGCAACCAGAATTTTCAAACTTAGATAATATTCTTAGATCAGCATGGAAATGG
CATAAAAAATTAAATGTAAATTTCTCAAAATGA

Upstream 100 bases:

>100_bases
GTTTTTTTCTAACTAAATTGATGATTTCTTTAATTACAAGGTTTATTTATAGACAAATTTCAATTAATATGAAGAATCTT
AAAATGAAAAAAGATTTAAA

Downstream 100 bases:

>100_bases
TCTTTTATAAGTAGATTTTTTATCAGGTTATATTGTAGTTTAAATAATAATATCTGAGCTTTTGTGAAATTTGAAAAGCT
ATTAGTTTATGGTCCTGGAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MHCKRIVVTGGAGYIGSHFCKTAFLKGHKTFVIDNLITGNYDFIKWGEFYKLDIREESSFKELLLKIKPDYLVHFAASAY
VSESIFKPLDYISNNIDGMRSVCKICSEIKIPIVFSSSCSVYGEAKNVPINESEPLNPLSPYGETKLFCEKILKWCSNAY
GLRWVSLRYFNAAGADEDLEIGEKHDPETHIIPLAIRALGDSGETLKIFGRDYDTFDGTAVRDFIHVMDLASAHLKAIEY
LAEGGMSNIFNLGSGNGTSIKSIINGLENISSKQVKLKYCERREEDPSCLFADISKAKSILNWQPEFSNLDNILRSAWKW
HKKLNVNFSK

Sequences:

>Translated_330_residues
MHCKRIVVTGGAGYIGSHFCKTAFLKGHKTFVIDNLITGNYDFIKWGEFYKLDIREESSFKELLLKIKPDYLVHFAASAY
VSESIFKPLDYISNNIDGMRSVCKICSEIKIPIVFSSSCSVYGEAKNVPINESEPLNPLSPYGETKLFCEKILKWCSNAY
GLRWVSLRYFNAAGADEDLEIGEKHDPETHIIPLAIRALGDSGETLKIFGRDYDTFDGTAVRDFIHVMDLASAHLKAIEY
LAEGGMSNIFNLGSGNGTSIKSIINGLENISSKQVKLKYCERREEDPSCLFADISKAKSILNWQPEFSNLDNILRSAWKW
HKKLNVNFSK
>Mature_330_residues
MHCKRIVVTGGAGYIGSHFCKTAFLKGHKTFVIDNLITGNYDFIKWGEFYKLDIREESSFKELLLKIKPDYLVHFAASAY
VSESIFKPLDYISNNIDGMRSVCKICSEIKIPIVFSSSCSVYGEAKNVPINESEPLNPLSPYGETKLFCEKILKWCSNAY
GLRWVSLRYFNAAGADEDLEIGEKHDPETHIIPLAIRALGDSGETLKIFGRDYDTFDGTAVRDFIHVMDLASAHLKAIEY
LAEGGMSNIFNLGSGNGTSIKSIINGLENISSKQVKLKYCERREEDPSCLFADISKAKSILNWQPEFSNLDNILRSAWKW
HKKLNVNFSK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=34.2028985507246, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=34.2028985507246, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=34.2028985507246, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=24.025974025974, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI7657641, Length=338, Percent_Identity=23.6686390532544, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=37.5375375375375, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1790049, Length=268, Percent_Identity=27.6119402985075, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994969, Length=351, Percent_Identity=22.5071225071225, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=353, Percent_Identity=33.4277620396601, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71982038, Length=355, Percent_Identity=33.2394366197183, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17539532, Length=333, Percent_Identity=23.1231231231231, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17568069, Length=331, Percent_Identity=25.0755287009063, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=339, Percent_Identity=35.693215339233, Blast_Score=183, Evalue=3e-47,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=34.8837209302326, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=23.9482200647249, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37184; Mature: 37184

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCKRIVVTGGAGYIGSHFCKTAFLKGHKTFVIDNLITGNYDFIKWGEFYKLDIREESSF
CCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECEECCCCCEEECCCEEEEEECCCCCH
KELLLKIKPDYLVHFAASAYVSESIFKPLDYISNNIDGMRSVCKICSEIKIPIVFSSSCS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCC
VYGEAKNVPINESEPLNPLSPYGETKLFCEKILKWCSNAYGLRWVSLRYFNAAGADEDLE
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCC
IGEKHDPETHIIPLAIRALGDSGETLKIFGRDYDTFDGTAVRDFIHVMDLASAHLKAIEY
CCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LAEGGMSNIFNLGSGNGTSIKSIINGLENISSKQVKLKYCERREEDPSCLFADISKAKSI
HHHCCCHHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
LNWQPEFSNLDNILRSAWKWHKKLNVNFSK
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHCKRIVVTGGAGYIGSHFCKTAFLKGHKTFVIDNLITGNYDFIKWGEFYKLDIREESSF
CCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECEECCCCCEEECCCEEEEEECCCCCH
KELLLKIKPDYLVHFAASAYVSESIFKPLDYISNNIDGMRSVCKICSEIKIPIVFSSSCS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCC
VYGEAKNVPINESEPLNPLSPYGETKLFCEKILKWCSNAYGLRWVSLRYFNAAGADEDLE
EEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCC
IGEKHDPETHIIPLAIRALGDSGETLKIFGRDYDTFDGTAVRDFIHVMDLASAHLKAIEY
CCCCCCCCCEEEEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LAEGGMSNIFNLGSGNGTSIKSIINGLENISSKQVKLKYCERREEDPSCLFADISKAKSI
HHHCCCHHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
LNWQPEFSNLDNILRSAWKWHKKLNVNFSK
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787800; 11481431; 8544814 [H]