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The map label for this gene is rfbB [C]

Identifier: 126696749

GI number: 126696749

Start: 1178122

End: 1179129

Strand: Reverse

Name: rfbB [C]

Synonym: P9301_14111

Alternate gene names: 126696749

Gene position: 1179129-1178122 (Counterclockwise)

Preceding gene: 126696750

Following gene: 126696748

Centisome position: 71.82

GC content: 29.76

Gene sequence:

>1008_bases
ATGAATAAAAATAGAAAAGTATTAGTTACTGGTGCAGATGGCTTTATAGGATCTCATTTAACGGAAATGCTTGTTAGAAA
AGGGTACGAAGTTAATGCTTTCTGTCTATACAATTCATTTGGATTGAAAGGTTGGTTGGATTTTGTTGCGCCTGAAATAA
AAAATAATATAAATTATATTTTTGGGGATATTAGAAATTATGACTCCATTTCAAAAGCAGTAAAATCAAATAATTTTGTT
TTTCATTTGGCAGCATTAATTGGAATTCCATATAGTTATACTTCTCCGTCAAGCTATGTTGATACTAATATCAAAGGAAC
TTTAAATGTTTTAGAAGCTTGTCGAAAATTTGATATTGAAAAACTCATCCATACATCAACTTCTGAAACTTACGGTTCTG
CTCAATATGTTCCAATTAATGAAGAACATCCATTAGTAGCTCAATCCCCATATGCCGCAACAAAGATTGCAGCAGACCAA
TTAGCTTTAAGTTTCTTTAAAAGTTTTAATACTCCAGTATCTATTTTAAGACCATTTAATACATATGGTCCTCGACAGAG
TTGCCGAGCTGTAATACCTTCTATAATTCTGCAAATCCTTGAAAAAAAGGAATTTATATCATTAGGATCTTTAATGCCAA
CAAGGGATTTCAATTACGTAAGTGATACCTGTGAAGCCTTTGAAAAGATTTGTATAAGTAATAAAACTACTGGACAAATT
TTAAATGCAGCAAGCGAATATGAAATTTCTATAGCTGATACAGTTAAAGAAATTTCAAAAATAATGAACTCTAAAATTTC
AATTATAAGTGACCAAAAAAGATTAAGGCCAGATAAATCTGAGGTAAATAGACTTTTTGGTGATAGTTCAAGGCTTCAAG
AACTTTCAAATTGGAAGCCAAAATATAAGGGTTTAGATGGATTTAGGGAAGGTATTAAAAAAACAATTGATTGGTTTATA
AATAATAGAAATAACACCCTTTATTCTGATAATAATTTTTCTTTATGA

Upstream 100 bases:

>100_bases
TTAAACCAAAAAATGTTTCATATCCTATTTTGTTTCTTCTCTCAGATCAAGCAAAAGGTATATCTGGTCAGAATTTAATA
GTTGATGATGGGTGGTCTTT

Downstream 100 bases:

>100_bases
CGAATATTATTTTTTGCAATGAGATTGTAGATGCAATAGAAAATGTAGTAAGAAAACCAAATCAAAGCAACGATATTTTG
TTGCATGAGCCATATTTTAA

Product: nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNKNRKVLVTGADGFIGSHLTEMLVRKGYEVNAFCLYNSFGLKGWLDFVAPEIKNNINYIFGDIRNYDSISKAVKSNNFV
FHLAALIGIPYSYTSPSSYVDTNIKGTLNVLEACRKFDIEKLIHTSTSETYGSAQYVPINEEHPLVAQSPYAATKIAADQ
LALSFFKSFNTPVSILRPFNTYGPRQSCRAVIPSIILQILEKKEFISLGSLMPTRDFNYVSDTCEAFEKICISNKTTGQI
LNAASEYEISIADTVKEISKIMNSKISIISDQKRLRPDKSEVNRLFGDSSRLQELSNWKPKYKGLDGFREGIKKTIDWFI
NNRNNTLYSDNNFSL

Sequences:

>Translated_335_residues
MNKNRKVLVTGADGFIGSHLTEMLVRKGYEVNAFCLYNSFGLKGWLDFVAPEIKNNINYIFGDIRNYDSISKAVKSNNFV
FHLAALIGIPYSYTSPSSYVDTNIKGTLNVLEACRKFDIEKLIHTSTSETYGSAQYVPINEEHPLVAQSPYAATKIAADQ
LALSFFKSFNTPVSILRPFNTYGPRQSCRAVIPSIILQILEKKEFISLGSLMPTRDFNYVSDTCEAFEKICISNKTTGQI
LNAASEYEISIADTVKEISKIMNSKISIISDQKRLRPDKSEVNRLFGDSSRLQELSNWKPKYKGLDGFREGIKKTIDWFI
NNRNNTLYSDNNFSL
>Mature_335_residues
MNKNRKVLVTGADGFIGSHLTEMLVRKGYEVNAFCLYNSFGLKGWLDFVAPEIKNNINYIFGDIRNYDSISKAVKSNNFV
FHLAALIGIPYSYTSPSSYVDTNIKGTLNVLEACRKFDIEKLIHTSTSETYGSAQYVPINEEHPLVAQSPYAATKIAADQ
LALSFFKSFNTPVSILRPFNTYGPRQSCRAVIPSIILQILEKKEFISLGSLMPTRDFNYVSDTCEAFEKICISNKTTGQI
LNAASEYEISIADTVKEISKIMNSKISIISDQKRLRPDKSEVNRLFGDSSRLQELSNWKPKYKGLDGFREGIKKTIDWFI
NNRNNTLYSDNNFSL

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=30.4477611940298, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI42516563, Length=345, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI4504031, Length=355, Percent_Identity=26.4788732394366, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI56237023, Length=335, Percent_Identity=25.3731343283582, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI56118217, Length=335, Percent_Identity=25.3731343283582, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI189083684, Length=335, Percent_Identity=25.3731343283582, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI193211614, Length=231, Percent_Identity=26.8398268398268, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI8393516, Length=231, Percent_Identity=26.8398268398268, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4504507, Length=187, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI218563686, Length=165, Percent_Identity=29.6969696969697, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI218563684, Length=165, Percent_Identity=29.6969696969697, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788353, Length=356, Percent_Identity=27.8089887640449, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI48994969, Length=343, Percent_Identity=25.6559766763848, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786974, Length=359, Percent_Identity=24.5125348189415, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788366, Length=339, Percent_Identity=26.2536873156342, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788589, Length=273, Percent_Identity=27.4725274725275, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788365, Length=346, Percent_Identity=21.9653179190751, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568069, Length=331, Percent_Identity=27.190332326284, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17539532, Length=327, Percent_Identity=26.605504587156, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17507723, Length=330, Percent_Identity=24.2424242424242, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115532424, Length=326, Percent_Identity=25.4601226993865, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17539422, Length=330, Percent_Identity=24.2424242424242, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI133901790, Length=330, Percent_Identity=24.2424242424242, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI133901788, Length=330, Percent_Identity=24.2424242424242, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI133901786, Length=330, Percent_Identity=24.2424242424242, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17539424, Length=330, Percent_Identity=24.2424242424242, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71982038, Length=351, Percent_Identity=24.7863247863248, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982035, Length=351, Percent_Identity=24.7863247863248, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71987463, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=191, Percent_Identity=31.9371727748691, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356223, Length=339, Percent_Identity=30.0884955752212, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24158427, Length=330, Percent_Identity=23.6363636363636, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19923002, Length=349, Percent_Identity=26.647564469914, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37826; Mature: 37826

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNRKVLVTGADGFIGSHLTEMLVRKGYEVNAFCLYNSFGLKGWLDFVAPEIKNNINYI
CCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEE
FGDIRNYDSISKAVKSNNFVFHLAALIGIPYSYTSPSSYVDTNIKGTLNVLEACRKFDIE
ECCCCCHHHHHHHHHCCCHHEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KLIHTSTSETYGSAQYVPINEEHPLVAQSPYAATKIAADQLALSFFKSFNTPVSILRPFN
HHHHCCCCCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
TYGPRQSCRAVIPSIILQILEKKEFISLGSLMPTRDFNYVSDTCEAFEKICISNKTTGQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LNAASEYEISIADTVKEISKIMNSKISIISDQKRLRPDKSEVNRLFGDSSRLQELSNWKP
HHCCCCCEEEHHHHHHHHHHHHCCHHHEECCHHHCCCCHHHHHHHHCCHHHHHHHHCCCC
KYKGLDGFREGIKKTIDWFINNRNNTLYSDNNFSL
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure
MNKNRKVLVTGADGFIGSHLTEMLVRKGYEVNAFCLYNSFGLKGWLDFVAPEIKNNINYI
CCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEE
FGDIRNYDSISKAVKSNNFVFHLAALIGIPYSYTSPSSYVDTNIKGTLNVLEACRKFDIE
ECCCCCHHHHHHHHHCCCHHEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KLIHTSTSETYGSAQYVPINEEHPLVAQSPYAATKIAADQLALSFFKSFNTPVSILRPFN
HHHHCCCCCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
TYGPRQSCRAVIPSIILQILEKKEFISLGSLMPTRDFNYVSDTCEAFEKICISNKTTGQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
LNAASEYEISIADTVKEISKIMNSKISIISDQKRLRPDKSEVNRLFGDSSRLQELSNWKP
HHCCCCCEEEHHHHHHHHHHHHCCHHHEECCHHHCCCCHHHHHHHHCCHHHHHHHHCCCC
KYKGLDGFREGIKKTIDWFINNRNNTLYSDNNFSL
CCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]