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The map label for this gene is pntA-2 [H]

Identifier: 126696674

GI number: 126696674

Start: 1117675

End: 1117968

Strand: Reverse

Name: pntA-2 [H]

Synonym: P9301_13361

Alternate gene names: 126696674

Gene position: 1117968-1117675 (Counterclockwise)

Preceding gene: 126696675

Following gene: 126696673

Centisome position: 68.09

GC content: 36.05

Gene sequence:

>294_bases
ATGTCTTTTATAAGTCTTCTTTGGGTTCTTTTACTAGGTAGTTTATTAGGTCTTGAGTTAATTGGAAAAGTTCCTCCTAC
TCTTCACACACCTCTAATGAGTGGAGCAAATGCAATTTCAGGAATAACAATGCTTGCAGCCTTGACTTTAATTGTAAAAG
CAGAAGGTAACGTACCACTTTTAATCATTGGTTCAGTTTCTCTTGGATTTGCTCTTTTCAACGTTGTAGGTGGTTTCTTT
GTAACTGATCGAATGCTCGCGATGTTTAGTCGTAAACCATCAAATAAGAAGTAA

Upstream 100 bases:

>100_bases
TAAATTAGATAAAGAGGATGAACTCATTTCTGGATGTTTATTAAGCGATGAAGGAGTTGTTCTTCAAAATAAAGTTTTTG
AAAATTGAGGTTTTAAAATT

Downstream 100 bases:

>100_bases
TTTTTAACATGAATCTACCTGTAATCATTAAATTCGTTATTGACCTTCTAGCAGTACTTTTACTGGCTTTGGGAATAAAA
GGATTGTCAAAAGTAAAATC

Product: putative nicotinamide nucleotide transhydrogenase, subunit alpha 2 (A2)

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha; Pyridine nucleotide transhydrogenase subunit alpha [H]

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSFISLLWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIVKAEGNVPLLIIGSVSLGFALFNVVGGFF
VTDRMLAMFSRKPSNKK

Sequences:

>Translated_97_residues
MSFISLLWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIVKAEGNVPLLIIGSVSLGFALFNVVGGFF
VTDRMLAMFSRKPSNKK
>Mature_96_residues
SFISLLWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIVKAEGNVPLLIIGSVSLGFALFNVVGGFFV
TDRMLAMFSRKPSNKK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR016040
- InterPro:   IPR004571 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10242; Mature: 10110

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFISLLWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIVKAEGNVPL
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCE
LIIGSVSLGFALFNVVGGFFVTDRMLAMFSRKPSNKK
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SFISLLWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIVKAEGNVPL
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCE
LIIGSVSLGFALFNVVGGFFVTDRMLAMFSRKPSNKK
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]