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The map label for this gene is clpC [H]

Identifier: 126696533

GI number: 126696533

Start: 1008419

End: 1010944

Strand: Reverse

Name: clpC [H]

Synonym: P9301_11951

Alternate gene names: 126696533

Gene position: 1010944-1008419 (Counterclockwise)

Preceding gene: 126696534

Following gene: 126696532

Centisome position: 61.57

GC content: 36.18

Gene sequence:

>2526_bases
ATGTTCGAAAGATTTACAGAAAAGGCTATAAAAGTCATTATGCTTGCTCAAGAGGAAGCTCGAAGACTTGGTCATAATTT
TGTTGGAACTGAACAAATTCTTTTGGGGTTAATTGGAGAAGGAACTGGGGTAGCAGCAAAAGTACTTAAATCACTTGGAG
TCAATTTAAAAGATTCAAGGATAGAGGTGGAAAAGATAATTGGTAGAGGTTCAGGATTTGTAGCTGTAGAAATACCTTTT
ACTCCCAGAGCTAAAAGAGTTTTGGAACTATCTTTGGAAGAGGCTCGTCAACTTGGCCACAATTACATTGGTACAGAACA
TTTATTGTTAGGTTTAATAAGAGAAGGTGAAGGTGTGGCTGCAAGAGTTCTTGAAAATCTTAATATTGACCTCACAAAAG
TTAGAACTCAAGTTATAAGGATGCTTGGTGAAACCGCCGAAGTTGGCACCGGGGGTAGCTCAAACAAGGGCAACTTAAAA
ACTGCTACCCTTGATGAATTCGGAACAAATTTAACAAAATTAGCAAGTGAATCAAAATTAGATCCAGTCGTTGGTCGCCA
TTCAGAAATAGATCGTGTCGTTCAAATACTAGGTAGGAGGACAAAAAATAATCCTGTTCTTATTGGGGAGCCAGGTGTAG
GTAAAACAGCTATCGCAGAAGGTTTAGCTCAAAGAATACAAACTGGCGATATTCCAGACATACTTGAAGATAAAAGAGTT
TTGACCCTTGATATAGGTCTTTTGGTAGCAGGAACAAAATATAGAGGTGAATTTGAAGAAAGGTTAAAAAAAATTATGGA
AGAAATTAAATCAGCGGGTAACGTCATTCTTGTCATAGATGAAGTGCATACTTTAATTGGTGCTGGAGCTGCTGAAGGAG
CTATAGATGCAGCAAATATACTTAAGCCAGCATTAGCTAGAGGGGAACTTCAATGTATTGGAGCAACAACTCTAGACGAA
TATAGAAAACATATTGAAAGAGATGCTGCTTTAGAAAGAAGATTCCAGCCTGTAATGGTTGGGGAACCATCCATAGAAGA
TACAATCGAAATTTTAAAAGGTCTCAGAGAGCGTTACGAACAACATCATCGACTAAAAATTACTGATGATGCCCTAGAGG
CCGCCGCTCATTTAGGTGATCGTTACATATCTGATAGGTTTTTACCTGATAAGGCTATTGACCTTATCGATGAGGCTGGA
AGTAGGGTGCGTTTAATAAACTCTAAACTTCCGCCTGAAGCAAAACAAATAGATAGAGAATTAAGACAAATCCAAAAACA
GAAGGAAGAATCTGTAAGAGACCAAAATTTTGATCAGGCTGGGCAATTACGCGAAAAAGAGATGGAATTGTCTGCAAAAA
TTAAAGAGGTTTTGGATAATAAGAAAGAATCTACAGCTGTAGATCAAACTGATCCTGATAATTCTGCAAAAAGTGATTCT
AAACTTTTACAAAGTCCTCTTGTCAGTGAAGAGGATGTAGCTCATATTGTGGCTTCATGGACAGGTGTTCCTGTTCAAAA
ATTAACAGAAACAGAATCAGTCAAGCTTCTCAATATGGAGGAAACACTTCACCAAAGACTGATTGGACAAGATGAAGCTG
TAAAGGCTGTGTCAAGAGCTATAAGAAGAGCAAGAGTTGGATTAAAAAATCCTAATAGACCCATAGCAAGTTTTATCTTT
TCTGGACCTACTGGTGTTGGTAAAACTGAATTGACTAAATCATTGGCTTCATATTTCTTCGGTAGTGAAGAAGCAATGAT
CAGATTAGATATGTCAGAATTCATGGAAAGACATACAGTTAGTAAACTTATAGGCTCTCCTCCTGGCTATGTTGGTTTTA
ATGAAGGTGGTCAGCTTACTGAAGCTGTTAGAAGACGCCCTTACACCGTTGTTTTATTTGATGAAGTTGAAAAGGCGCAT
CCAGATGTTTTTAACTTATTATTGCAACTACTTGAAGACGGAAGATTAACTGACTCCAAAGGGAGAACTGTAGATTTTAA
AAATACATTATTAATAATGACCTCTAATATCGGTTCAAAAGTTATCGAAAAAGGTGGTGGTGGACTAGGTTTTGAATTCT
CAGGTGATTCAGTTGAAGATAGCCAATATAATAGAATTAAATCACTAGTTAATGAAGAACTTAAGCAATACTTTAGGCCT
GAATTTTTAAATAGACTTGATGAAATAATTGTATTTAGACAATTAACTAAAAATGAAGTTAAAGAAATTGCTGAAATAAT
GTTGCAAGAAGTTTTTATCCGACTACAAGATAAAGGTATTAAATTAAATGTCACCGATGCTTTTAAAGAAAGACTTGTTG
AAGAAGGTTACAATCCTTCATACGGAGCGAGACCTTTAAGAAGGGCAGTTATGCGTTTACTAGAAGATAGTTTGGCTGAA
GAAGTTCTTTCTGGAAGAATTAAAGACGGAGATAATGCTTTAGTTGATATAGATGATAATAAAAAAGTTACTATAAATAT
TTCTTCTGAAGAATCTTCTCAAGAGCTAGCAGGTGCTAACTTCTAA

Upstream 100 bases:

>100_bases
TTAATTTGATAAATTATACTTTTGGGTATTCACAAAAGCTCATTCTGAACACAAAATTGACATATTACTGGTAGGTTATT
AATAGGAATTTAATCTTCTA

Downstream 100 bases:

>100_bases
TTATTCAAAGTAAATATGCAGTCTATCTCTCCAGAAACAATATACAGGGGAAATTCTGCTTGGGAAAAATCTTTACCTCA
GATTACTAAATTAACTAAAA

Product: ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 841; Mature: 841

Protein sequence:

>841_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLNIDLTKVRTQVIRMLGETAEVGTGGSSNKGNLK
TATLDEFGTNLTKLASESKLDPVVGRHSEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQTGDIPDILEDKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEAG
SRVRLINSKLPPEAKQIDRELRQIQKQKEESVRDQNFDQAGQLREKEMELSAKIKEVLDNKKESTAVDQTDPDNSAKSDS
KLLQSPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRAIRRARVGLKNPNRPIASFIF
SGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAH
PDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFRP
EFLNRLDEIIVFRQLTKNEVKEIAEIMLQEVFIRLQDKGIKLNVTDAFKERLVEEGYNPSYGARPLRRAVMRLLEDSLAE
EVLSGRIKDGDNALVDIDDNKKVTINISSEESSQELAGANF

Sequences:

>Translated_841_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLNIDLTKVRTQVIRMLGETAEVGTGGSSNKGNLK
TATLDEFGTNLTKLASESKLDPVVGRHSEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQTGDIPDILEDKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEAG
SRVRLINSKLPPEAKQIDRELRQIQKQKEESVRDQNFDQAGQLREKEMELSAKIKEVLDNKKESTAVDQTDPDNSAKSDS
KLLQSPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRAIRRARVGLKNPNRPIASFIF
SGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAH
PDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFRP
EFLNRLDEIIVFRQLTKNEVKEIAEIMLQEVFIRLQDKGIKLNVTDAFKERLVEEGYNPSYGARPLRRAVMRLLEDSLAE
EVLSGRIKDGDNALVDIDDNKKVTINISSEESSQELAGANF
>Mature_841_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSRIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLNIDLTKVRTQVIRMLGETAEVGTGGSSNKGNLK
TATLDEFGTNLTKLASESKLDPVVGRHSEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQTGDIPDILEDKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYEQHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEAG
SRVRLINSKLPPEAKQIDRELRQIQKQKEESVRDQNFDQAGQLREKEMELSAKIKEVLDNKKESTAVDQTDPDNSAKSDS
KLLQSPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRAIRRARVGLKNPNRPIASFIF
SGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAH
PDVFNLLLQLLEDGRLTDSKGRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFRP
EFLNRLDEIIVFRQLTKNEVKEIAEIMLQEVFIRLQDKGIKLNVTDAFKERLVEEGYNPSYGARPLRRAVMRLLEDSLAE
EVLSGRIKDGDNALVDIDDNKKVTINISSEESSQELAGANF

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=324, Percent_Identity=37.037037037037, Blast_Score=204, Evalue=4e-52,
Organism=Escherichia coli, GI1788943, Length=881, Percent_Identity=46.1975028376845, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=822, Percent_Identity=36.7396593673966, Blast_Score=505, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6320464, Length=709, Percent_Identity=48.2369534555712, Blast_Score=636, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=892, Percent_Identity=36.322869955157, Blast_Score=543, Evalue=1e-155,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93386; Mature: 93386

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50151 UVR ; PS00036 BZIP_BASIC ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLNIDLTKVRTQVIRMLGETAEVGTGGSSNKGNLKTATLDEFGTNLTKLASESKL
HHHHHHCCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHCCC
DPVVGRHSEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQTGDIPDILEDKRV
CCHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHCCCEE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYE
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
QHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEAGSRVRLINSKLPPEAKQIDRE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LRQIQKQKEESVRDQNFDQAGQLREKEMELSAKIKEVLDNKKESTAVDQTDPDNSAKSDS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHH
KLLQSPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRA
HHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHHHH
IRRARVGLKNPNRPIASFIFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTV
HHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHH
SKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAHPDVFNLLLQLLEDGRLTDSK
HHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCCC
GRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFRP
CCEEEECCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCH
EFLNRLDEIIVFRQLTKNEVKEIAEIMLQEVFIRLQDKGIKLNVTDAFKERLVEEGYNPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCC
YGARPLRRAVMRLLEDSLAEEVLSGRIKDGDNALVDIDDNKKVTINISSEESSQELAGAN
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHCCCC
F
C
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSLGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLNIDLTKVRTQVIRMLGETAEVGTGGSSNKGNLKTATLDEFGTNLTKLASESKL
HHHHHHCCCHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEHHHHCCHHHHHHHHCCC
DPVVGRHSEIDRVVQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQTGDIPDILEDKRV
CCHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHCCCEE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIEDTIEILKGLRERYE
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHH
QHHRLKITDDALEAAAHLGDRYISDRFLPDKAIDLIDEAGSRVRLINSKLPPEAKQIDRE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LRQIQKQKEESVRDQNFDQAGQLREKEMELSAKIKEVLDNKKESTAVDQTDPDNSAKSDS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHH
KLLQSPLVSEEDVAHIVASWTGVPVQKLTETESVKLLNMEETLHQRLIGQDEAVKAVSRA
HHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHHCCCHHHHHHHHHH
IRRARVGLKNPNRPIASFIFSGPTGVGKTELTKSLASYFFGSEEAMIRLDMSEFMERHTV
HHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHH
SKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEVEKAHPDVFNLLLQLLEDGRLTDSK
HHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHHCCCCCCCC
GRTVDFKNTLLIMTSNIGSKVIEKGGGGLGFEFSGDSVEDSQYNRIKSLVNEELKQYFRP
CCEEEECCEEEEEECCCCHHHHHCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCH
EFLNRLDEIIVFRQLTKNEVKEIAEIMLQEVFIRLQDKGIKLNVTDAFKERLVEEGYNPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCC
YGARPLRRAVMRLLEDSLAEEVLSGRIKDGDNALVDIDDNKKVTINISSEESSQELAGAN
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]