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The map label for this gene is ruvA

Identifier: 126696254

GI number: 126696254

Start: 788678

End: 789355

Strand: Reverse

Name: ruvA

Synonym: P9301_09161

Alternate gene names: 126696254

Gene position: 789355-788678 (Counterclockwise)

Preceding gene: 126696255

Following gene: 126696253

Centisome position: 48.08

GC content: 25.07

Gene sequence:

>678_bases
TTGATTAGTTGGATAAATGGAGATTTAGTTGATTTATGGCAAACTAATCAAAAATTTTTTGTTTTAATAAATTGTCAAGG
ATTAGGATACGAAATACAAATACTAGAATCCTTTTTTCTCAAATTAAGAAAAAATCAGATATCTACTAAAAACATCACTC
TTTGGGTAAAGCATATAAAAAAAGAAGATTCAGATTTATTATTTGGCTTTACATCAAATGAGCAAAAGAATTTCTTTATT
GAAATTTTAAGTATTCGAGGTGTTGGATCTCAAATTGGTATTGGGATATTAAACAAATTTTCTATTAGTGAAGTTATAAA
TGCAATAAAAACACAAGACAAAAAATTAATATGTTCTGTACCTGGTATAGGACAAAAAATGAGTGAGCGTTTAATTTTAG
AATTAAAAAGTAAATTTAAAAGCGAAATATTATCTGAAGAAGAAAAAAGCAAAGGTGAACTTGAGATTAAGGATCCTGAA
ATAAATAAAATGATAGAAGACCTTCAGTTAACCCTTCAATCATTAAGTTACAAAAACAAAGAAATAAATAACATTTTGCC
AATTATTATTAAAGAAATTGATCTCTTAGGTAAAAAAGAAAATAATTTATCATTTGAAAAACTATTGAAATTAGCTATGC
GTTATCTAGATGAGGATAGTAGTAATATAGCTAGATGA

Upstream 100 bases:

>100_bases
AATTGCATTATCCTCATCTAGAGGGAAAGACAGGTTTTGGGCCGTACCAGCGGGCGGTACTGCAGGAGCTCTAATTGGAT
GTCAGGTGGATGGTGGTTAA

Downstream 100 bases:

>100_bases
CGTAGTATCATAGATTAAAAGAAATAAATTTTATGTCATTAGATACAGCTGAAAAACAGAAGCTGATTGAAAATCATCAA
GTACATCCGACTGATACAGG

Product: putative holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MISWINGDLVDLWQTNQKFFVLINCQGLGYEIQILESFFLKLRKNQISTKNITLWVKHIKKEDSDLLFGFTSNEQKNFFI
EILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSVPGIGQKMSERLILELKSKFKSEILSEEEKSKGELEIKDPE
INKMIEDLQLTLQSLSYKNKEINNILPIIIKEIDLLGKKENNLSFEKLLKLAMRYLDEDSSNIAR

Sequences:

>Translated_225_residues
MISWINGDLVDLWQTNQKFFVLINCQGLGYEIQILESFFLKLRKNQISTKNITLWVKHIKKEDSDLLFGFTSNEQKNFFI
EILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSVPGIGQKMSERLILELKSKFKSEILSEEEKSKGELEIKDPE
INKMIEDLQLTLQSLSYKNKEINNILPIIIKEIDLLGKKENNLSFEKLLKLAMRYLDEDSSNIAR
>Mature_225_residues
MISWINGDLVDLWQTNQKFFVLINCQGLGYEIQILESFFLKLRKNQISTKNITLWVKHIKKEDSDLLFGFTSNEQKNFFI
EILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSVPGIGQKMSERLILELKSKFKSEILSEEEKSKGELEIKDPE
INKMIEDLQLTLQSLSYKNKEINNILPIIIKEIDLLGKKENNLSFEKLLKLAMRYLDEDSSNIAR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=218, Percent_Identity=25.6880733944954, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_PROM0 (A3PCR4)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091140.1
- ProteinModelPortal:   A3PCR4
- SMR:   A3PCR4
- STRING:   A3PCR4
- GeneID:   4912324
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_09161
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   ISWINGD
- ProtClustDB:   CLSK922035
- BioCyc:   PMAR167546:P9301ORF_0933-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278

Pfam domain/function: PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like

EC number: =3.6.4.12

Molecular weight: Translated: 25928; Mature: 25928

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISWINGDLVDLWQTNQKFFVLINCQGLGYEIQILESFFLKLRKNQISTKNITLWVKHIK
CCCCCCCCEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHC
KEDSDLLFGFTSNEQKNFFIEILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSV
CCCCCEEEEECCCCCCEEEEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHCCCCEEEEEC
PGIGQKMSERLILELKSKFKSEILSEEEKSKGELEIKDPEINKMIEDLQLTLQSLSYKNK
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
EINNILPIIIKEIDLLGKKENNLSFEKLLKLAMRYLDEDSSNIAR
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISWINGDLVDLWQTNQKFFVLINCQGLGYEIQILESFFLKLRKNQISTKNITLWVKHIK
CCCCCCCCEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEHHC
KEDSDLLFGFTSNEQKNFFIEILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSV
CCCCCEEEEECCCCCCEEEEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHCCCCEEEEEC
PGIGQKMSERLILELKSKFKSEILSEEEKSKGELEIKDPEINKMIEDLQLTLQSLSYKNK
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
EINNILPIIIKEIDLLGKKENNLSFEKLLKLAMRYLDEDSSNIAR
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA