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The map label for this gene is pncA [C]

Identifier: 126696001

GI number: 126696001

Start: 589405

End: 589974

Strand: Reverse

Name: pncA [C]

Synonym: P9301_06631

Alternate gene names: 126696001

Gene position: 589974-589405 (Counterclockwise)

Preceding gene: 126696003

Following gene: 126696000

Centisome position: 35.93

GC content: 28.07

Gene sequence:

>570_bases
ATGATGAATGATCAAGAAATCTCTTTTGATAAATTATCATCGAAAGTAAACGCCTTGATAATTATTGATATTCAGGAAAA
AATAATAAGACCAATTTTTAATAAGGATTCAATAATCAAAAACATTAAAAAGCTTACAAATGCTTACCAAATTTTAGAAG
AAAACATATTTATATCTGAACAGAACCCAATCAAATTGGGAGTAACGATACCTGAATTATCACCAATAGCAGAATTTAGA
AAATTTGAAAAAATGGAATTCAGCCTAGCTAAAATAGAAGATTTTTTAAAAGAACTTAAAGATAAGAAAATTACTAATTT
GATAGTTTGTGGGATCGAAACGCATATTTGTATTCAACAAACAGTCTTAGATTGTTTACAAAAAGGATTTGAAGTTACTC
TCATATCAGATTCCATGGGAAGTCGAAGTAGAGTAGATCATGAAATAGCCTTACAAAGAATGACTCAGAGTGGGGCGATC
TTAACAACAACTGAATCAATAATTTTTGAATTATGCAAAACTGCGGATAGAGAAGAATTTAAAGAAATTAGAAACATAAT
AATGAGTTAA

Upstream 100 bases:

>100_bases
TTCTCAATAATAACTCTAGATGAGAGTAATACAACTTATTGATTTAAAATGTTTACTAAAGTTCTTCAAAATATTATGTT
AAATGTATCTTTATACATAA

Downstream 100 bases:

>100_bases
AGAAAAATAAAGACTGGCTTGTTGTTTTGAGATAATTTAAAATTTTATTAAAGATAAAATTTAAGGGTTTATTTGAATAT
GAAATTAGTTACTGAAAACT

Product: isochorismatase hydrolase family protein

Products: NA

Alternate protein names: Isochorismatase Family Protein; Isochorismatase Superfamily Hydrolase; Isochorismatase Hydrolase Family Protein; Nicotinamidase-Like Amidase; Amidase; Isochorismatase Family Hydrolase; Isochorismatase Domain-Containing; Hydrolase; Hydrolase Isochorismatase Family; Amidohydrolase; Hydrolase Isochorismatase; Amidase Related Nicotinamidase; YcaC Like Amidohydrolase; Isochorismatase Family; Nicotinamidase; YcaC-Related Amidohydrolase; Isochorismatase Domain-Containing A; Isochorismatase Hydrolase Family; Nicotinamidase-Related Amidase

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MMNDQEISFDKLSSKVNALIIIDIQEKIIRPIFNKDSIIKNIKKLTNAYQILEENIFISEQNPIKLGVTIPELSPIAEFR
KFEKMEFSLAKIEDFLKELKDKKITNLIVCGIETHICIQQTVLDCLQKGFEVTLISDSMGSRSRVDHEIALQRMTQSGAI
LTTTESIIFELCKTADREEFKEIRNIIMS

Sequences:

>Translated_189_residues
MMNDQEISFDKLSSKVNALIIIDIQEKIIRPIFNKDSIIKNIKKLTNAYQILEENIFISEQNPIKLGVTIPELSPIAEFR
KFEKMEFSLAKIEDFLKELKDKKITNLIVCGIETHICIQQTVLDCLQKGFEVTLISDSMGSRSRVDHEIALQRMTQSGAI
LTTTESIIFELCKTADREEFKEIRNIIMS
>Mature_189_residues
MMNDQEISFDKLSSKVNALIIIDIQEKIIRPIFNKDSIIKNIKKLTNAYQILEENIFISEQNPIKLGVTIPELSPIAEFR
KFEKMEFSLAKIEDFLKELKDKKITNLIVCGIETHICIQQTVLDCLQKGFEVTLISDSMGSRSRVDHEIALQRMTQSGAI
LTTTESIIFELCKTADREEFKEIRNIIMS

Specific function: Unknown

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI209969695, Length=187, Percent_Identity=33.6898395721925, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI13376007, Length=203, Percent_Identity=31.5270935960591, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI103471987, Length=185, Percent_Identity=31.8918918918919, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540156, Length=192, Percent_Identity=36.4583333333333, Blast_Score=116, Evalue=9e-27,
Organism=Drosophila melanogaster, GI19922924, Length=180, Percent_Identity=32.2222222222222, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357489, Length=172, Percent_Identity=31.3953488372093, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21728; Mature: 21728

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNDQEISFDKLSSKVNALIIIDIQEKIIRPIFNKDSIIKNIKKLTNAYQILEENIFISE
CCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEECC
QNPIKLGVTIPELSPIAEFRKFEKMEFSLAKIEDFLKELKDKKITNLIVCGIETHICIQQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
TVLDCLQKGFEVTLISDSMGSRSRVDHEIALQRMTQSGAILTTTESIIFELCKTADREEF
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHH
KEIRNIIMS
HHHHHHHCC
>Mature Secondary Structure
MMNDQEISFDKLSSKVNALIIIDIQEKIIRPIFNKDSIIKNIKKLTNAYQILEENIFISE
CCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCEEECC
QNPIKLGVTIPELSPIAEFRKFEKMEFSLAKIEDFLKELKDKKITNLIVCGIETHICIQQ
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHH
TVLDCLQKGFEVTLISDSMGSRSRVDHEIALQRMTQSGAILTTTESIIFELCKTADREEF
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHH
KEIRNIIMS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA