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The map label for this gene is mscS [C]

Identifier: 126696000

GI number: 126696000

Start: 588295

End: 589326

Strand: Reverse

Name: mscS [C]

Synonym: P9301_06621

Alternate gene names: 126696000

Gene position: 589326-588295 (Counterclockwise)

Preceding gene: 126696001

Following gene: 126695998

Centisome position: 35.89

GC content: 29.55

Gene sequence:

>1032_bases
ATGAAATTAGTTACTGAAAACTTCCTTCTGGCAATATCTATTTTTTTCATTGGAACTTTATTGTCGATAATAATTTCAAA
AGTTTCAAAAATATTTTTTAAAAAGATTTCCAAAAGAACAAAAACAAATTTCGATGATTTTATTTTTGAGGTGATCTCTG
GAATCATAAAACCTATAGGTTTCCTCCTATCATTTTATTTTTCAATTGACTATTTTTTTGCTGATGAAATAACTTTCATC
TCTGTCATATTGAATATTTTGAAATTATTTATATTAATAATCATCATAAAAGCTCTCAACAAAGTTTTAATAAGATCTTT
AACAGAAACGACCTCGAAAATTAATGATTCCTCAATTAGTTCGATGGTATCTTCACTAACCCCATTGATAAAAGCATTAA
CATGGACTATTGGCTCAATTTTTTTCTTACAAAATATAGGTGTTCAAATGACTGCTATTTGGGCTTTACTAAGTGCAGGA
GGTATTGGAGCAGGACTAGCTTTGAAAGATCCAGTTCAGGAGTTCTTTGAATATATAACAATTTTGCTTGATAAACCTTT
TCAAAAAGGTGAGTTTATAAAATCTGATGGAGTCCTCGGAATGGTTGAGAGAGTTGGAGTAAGATCATCAAGGATAAGAA
GTATTAATGGAGAAGTAATAGTAATGAGTAATAGCGCCCTAACAAATGGAATAATTTCAAATTACGCACAAATGGAAAAA
AGAAGGTTAGTACATAAATTGGGAGTAGTTTATGAAACCTCTCCAAAACTTATGAAATTGATTCCAATAATAATTAAAAA
AATAGTTGAAGAGACAAAAGATGCTTCTTTTGATAGATGTCATTTCACAGATTTCGGAGACTTCAGTCTTAATTTCGAAC
TTGTTTATTACATCCCAACAAATAATTATCTCGCCGCAATGGAAGCGCAACAATCTATAAATTTAAGAATTATTGAGGAA
TTTGCGTTTAATAATATAGAGTTTGCATTCCCAACACAAACCTTAAATATTGAAAGTAACAAAGCCAAATGA

Upstream 100 bases:

>100_bases
TAGAAACATAATAATGAGTTAAAGAAAAATAAAGACTGGCTTGTTGTTTTGAGATAATTTAAAATTTTATTAAAGATAAA
ATTTAAGGGTTTATTTGAAT

Downstream 100 bases:

>100_bases
TCTACAAATCTCTTCACTTAAAATCCAGAGTTTTGAAGCTAACTCAGAATTATTTGCCTCATCACTAACCTTACTTTCAA
CTAATTTATGTTTCTTAAAA

Product: small mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKLVTENFLLAISIFFIGTLLSIIISKVSKIFFKKISKRTKTNFDDFIFEVISGIIKPIGFLLSFYFSIDYFFADEITFI
SVILNILKLFILIIIIKALNKVLIRSLTETTSKINDSSISSMVSSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPTNNYLAAMEAQQSINLRIIEE
FAFNNIEFAFPTQTLNIESNKAK

Sequences:

>Translated_343_residues
MKLVTENFLLAISIFFIGTLLSIIISKVSKIFFKKISKRTKTNFDDFIFEVISGIIKPIGFLLSFYFSIDYFFADEITFI
SVILNILKLFILIIIIKALNKVLIRSLTETTSKINDSSISSMVSSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPTNNYLAAMEAQQSINLRIIEE
FAFNNIEFAFPTQTLNIESNKAK
>Mature_343_residues
MKLVTENFLLAISIFFIGTLLSIIISKVSKIFFKKISKRTKTNFDDFIFEVISGIIKPIGFLLSFYFSIDYFFADEITFI
SVILNILKLFILIIIIKALNKVLIRSLTETTSKINDSSISSMVSSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAG
GIGAGLALKDPVQEFFEYITILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPTNNYLAAMEAQQSINLRIIEE
FAFNNIEFAFPTQTLNIESNKAK

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1787591, Length=270, Percent_Identity=26.6666666666667, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789291, Length=282, Percent_Identity=25.886524822695, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 38709; Mature: 38709

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVTENFLLAISIFFIGTLLSIIISKVSKIFFKKISKRTKTNFDDFIFEVISGIIKPIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLSFYFSIDYFFADEITFISVILNILKLFILIIIIKALNKVLIRSLTETTSKINDSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SMVSSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAGGIGAGLALKDPVQEFFEYIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
HHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECC
NNYLAAMEAQQSINLRIIEEFAFNNIEFAFPTQTLNIESNKAK
CCEEEEEHHHHCCCCEEEHHHHCCCCEEECCCEEEECCCCCCC
>Mature Secondary Structure
MKLVTENFLLAISIFFIGTLLSIIISKVSKIFFKKISKRTKTNFDDFIFEVISGIIKPIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLLSFYFSIDYFFADEITFISVILNILKLFILIIIIKALNKVLIRSLTETTSKINDSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SMVSSLTPLIKALTWTIGSIFFLQNIGVQMTAIWALLSAGGIGAGLALKDPVQEFFEYIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ILLDKPFQKGEFIKSDGVLGMVERVGVRSSRIRSINGEVIVMSNSALTNGIISNYAQMEK
HHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
RRLVHKLGVVYETSPKLMKLIPIIIKKIVEETKDASFDRCHFTDFGDFSLNFELVYYIPT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECC
NNYLAAMEAQQSINLRIIEEFAFNNIEFAFPTQTLNIESNKAK
CCEEEEEHHHHCCCCEEEHHHHCCCCEEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]