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The map label for this gene is lepB [H]

Identifier: 126695970

GI number: 126695970

Start: 559603

End: 560187

Strand: Reverse

Name: lepB [H]

Synonym: P9301_06321

Alternate gene names: 126695970

Gene position: 560187-559603 (Counterclockwise)

Preceding gene: 126695975

Following gene: 126695969

Centisome position: 34.12

GC content: 31.62

Gene sequence:

>585_bases
ATGTCTACAACTCAAGAAAAAAGAAATTCAATACTAAGGGATTTAAAAAATCTTTTAATCTGGATATCTATAGCTTTAAT
TATACGATGGCAGGTTATAGAGCCAAGATGGATCCCATCCGGTTCCATGCTTCCAACTCTTCAAATACAAGATAAAATTC
TTGTTGAAAAATTAACCCCTAAAATCACATCCAAATCAAATCTTGCAAAATTAAAAAATAAAATAGTTGTTTTTAACGTT
CCGGAACAATTAATTAATGCTGGTTATGAGGCAGATACTGCACTAATAAAAAGAGTAATTGGAACCCCAGGTGACAAGGT
AGAAGTTAGAGACGGTAACCTTTACTTAAATGATATCGCCCAAAGAAATTACTTTTTTGACCAAAATATTAACTATTCTA
TTGGGCCTTTTATTGTTCCAGAAGACTCATTATGGGTGATGGGAGATAATAGAAATAATAGTATGGACTCACATATTTGG
GGGTTTTTACCCTATAAAAAAGTTATTGGTAAAGCTATTTTTAGATATTGGCCTTTTAATAAAATTGGACCTATTCGGTT
CCCTGCCCTTAATAATTTAGATTAA

Upstream 100 bases:

>100_bases
AAAAGTTGTAAACTTCTAAGAAAATTTTGGCATTCAATAGATGATGTCATAATTTACATAAATGCTTTGGGATTTTCCTC
ATAACTGAATTAAATAAAAA

Downstream 100 bases:

>100_bases
TGGGTACTTGATGTTGTAGGGTTTTTATATCTTGAAGCTGTAGAAATGTTTAATCCAGAATTTCTTGCTACTGAAAATAA
TGATCCAAACGATGAAAATG

Product: leader peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSTTQEKRNSILRDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKLTPKITSKSNLAKLKNKIVVFNV
PEQLINAGYEADTALIKRVIGTPGDKVEVRDGNLYLNDIAQRNYFFDQNINYSIGPFIVPEDSLWVMGDNRNNSMDSHIW
GFLPYKKVIGKAIFRYWPFNKIGPIRFPALNNLD

Sequences:

>Translated_194_residues
MSTTQEKRNSILRDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKLTPKITSKSNLAKLKNKIVVFNV
PEQLINAGYEADTALIKRVIGTPGDKVEVRDGNLYLNDIAQRNYFFDQNINYSIGPFIVPEDSLWVMGDNRNNSMDSHIW
GFLPYKKVIGKAIFRYWPFNKIGPIRFPALNNLD
>Mature_193_residues
STTQEKRNSILRDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKLTPKITSKSNLAKLKNKIVVFNVP
EQLINAGYEADTALIKRVIGTPGDKVEVRDGNLYLNDIAQRNYFFDQNINYSIGPFIVPEDSLWVMGDNRNNSMDSHIWG
FLPYKKVIGKAIFRYWPFNKIGPIRFPALNNLD

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22371; Mature: 22240

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTQEKRNSILRDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKLTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEECCCCCCCEEEEHHHHHHHHHHCC
KITSKSNLAKLKNKIVVFNVPEQLINAGYEADTALIKRVIGTPGDKVEVRDGNLYLNDIA
CCCCCHHHHHHHCCEEEEECCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECHH
QRNYFFDQNINYSIGPFIVPEDSLWVMGDNRNNSMDSHIWGFLPYKKVIGKAIFRYWPFN
HCCEEECCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC
KIGPIRFPALNNLD
CCCCEECCCCCCCC
>Mature Secondary Structure 
STTQEKRNSILRDLKNLLIWISIALIIRWQVIEPRWIPSGSMLPTLQIQDKILVEKLTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEECCCCCCCEEEEHHHHHHHHHHCC
KITSKSNLAKLKNKIVVFNVPEQLINAGYEADTALIKRVIGTPGDKVEVRDGNLYLNDIA
CCCCCHHHHHHHCCEEEEECCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCEEEECHH
QRNYFFDQNINYSIGPFIVPEDSLWVMGDNRNNSMDSHIWGFLPYKKVIGKAIFRYWPFN
HCCEEECCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC
KIGPIRFPALNNLD
CCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]