Click here to switch to the map view.

The map label for this gene is trpS [H]

Identifier: 126695962

GI number: 126695962

Start: 552544

End: 553560

Strand: Reverse

Name: trpS [H]

Synonym: P9301_06241

Alternate gene names: 126695962

Gene position: 553560-552544 (Counterclockwise)

Preceding gene: 126695963

Following gene: 126695961

Centisome position: 33.72

GC content: 32.15

Gene sequence:

>1017_bases
ATGGCAAATAAAAAAAGAATTCTTTCGGGAGTTCAACCAACTGGTGATTTACATATTGGGAATTGGCTTGGGGCCATAAA
TAATTGGGTTACGCTTCAAGAGCAATATGAAACATTTCTATGTGTAGTTGATTTGCACGCAATAACAGCCTCATATAATC
CCAAAGAATTATCTAAAAACACTTTCTCTACAGCGGCTTTATACGTCGCTTGTGGGATAGATCCCAATATATGCTCAATT
TTTGTCCAAAGTCAGATTTCAGCGCATTCAGAACTTTGTTGGATATTAAATTGCATGACCCCAATAAATTGGATGGAAAG
AATGATTCAATTTAAAGAAAAATCCATACAACAAGGTAATAATGTATCTATTGGATTATTTGACTATCCAATACTTATGG
CTGCAGACATCCTTCTTTATGATGCTGACTTCGTACCAGTAGGTGAGGATCAAAAACAACATCTTGAACTTGCGAGAGAT
ATTGCACAACAGAGAATTAATGCCAGATTTAGTAAGGATAAAAATATTTTAAAGATCCCTCAACCAATCATCATGAAGAA
TGGTTCAAAAATAATGAGTTTAATTGATGGTTCAAAAAAGATGAGTAAAAGTGATCCTAATGAGGGCAGTCGCATTAACT
TATTAGATCCTCCTGAAATAATCACAAAAAAAATCAAAAGAGCAAAAAGTGATAGTTCTATTGGAATTGAATTTAACAAC
CCTGAGAGACCAGAATCTAAAAATCTTATGATGATTTATTCAATATTGTCTGGCAAAGAAATTTCTCAATGTGAAAATGA
ATTCTTAGAGACTGGATGGGGGACATTTAAAAAATTAATTACCGAACAACTTATTGAATCACTAGAACCTATTCAGAAAA
AATATAAATTATTAATGAATGATCCCTATCAACTAAGTAAAATCCTTAATGAAGGGAAGGAAAAAGCTGAAGATTTAGCG
AATCAGACTTTAAAAAGAGTTAAATCAAAATTGGGATTTTTTGAAATGGAGAAATAA

Upstream 100 bases:

>100_bases
AATTCTTATGAAGAAAAGACAAAAACAGCACCTGATCCTTTTGCGAGACCTGTAAAAAGTGCATCAACTGAAGAGATCCA
ATCTAGCGAAGTAGAAGAGG

Downstream 100 bases:

>100_bases
ATTATGCCAATAATTACCTTGCCTGATGGTTCAAAGAAGGTTTTCGAAAAATCTGTAACTATTTTAGAAATTGCCCAGAG
TATAGGCGCTGGATTAGCTA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MANKKRILSGVQPTGDLHIGNWLGAINNWVTLQEQYETFLCVVDLHAITASYNPKELSKNTFSTAALYVACGIDPNICSI
FVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYDADFVPVGEDQKQHLELARD
IAQQRINARFSKDKNILKIPQPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
PERPESKNLMMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLMNDPYQLSKILNEGKEKAEDLA
NQTLKRVKSKLGFFEMEK

Sequences:

>Translated_338_residues
MANKKRILSGVQPTGDLHIGNWLGAINNWVTLQEQYETFLCVVDLHAITASYNPKELSKNTFSTAALYVACGIDPNICSI
FVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYDADFVPVGEDQKQHLELARD
IAQQRINARFSKDKNILKIPQPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
PERPESKNLMMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLMNDPYQLSKILNEGKEKAEDLA
NQTLKRVKSKLGFFEMEK
>Mature_337_residues
ANKKRILSGVQPTGDLHIGNWLGAINNWVTLQEQYETFLCVVDLHAITASYNPKELSKNTFSTAALYVACGIDPNICSIF
VQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGNNVSIGLFDYPILMAADILLYDADFVPVGEDQKQHLELARDI
AQQRINARFSKDKNILKIPQPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNNP
ERPESKNLMMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLMNDPYQLSKILNEGKEKAEDLAN
QTLKRVKSKLGFFEMEK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=36.9369369369369, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI41352700, Length=162, Percent_Identity=48.7654320987654, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=44.9848024316109, Blast_Score=300, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI71982800, Length=337, Percent_Identity=33.8278931750742, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI71982793, Length=337, Percent_Identity=33.8278931750742, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=37.6436781609195, Blast_Score=202, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=40.5405405405405, Blast_Score=253, Evalue=9e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38397; Mature: 38266

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKKRILSGVQPTGDLHIGNWLGAINNWVTLQEQYETFLCVVDLHAITASYNPKELSKN
CCCHHHHHCCCCCCCCEEHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
TFSTAALYVACGIDPNICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGN
HHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
NVSIGLFDYPILMAADILLYDADFVPVGEDQKQHLELARDIAQQRINARFSKDKNILKIP
CEEEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
QPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
CHHHHCCCHHHHHHHCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECC
PERPESKNLMMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLMN
CCCCCCCCEEEEEEHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPYQLSKILNEGKEKAEDLANQTLKRVKSKLGFFEMEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
ANKKRILSGVQPTGDLHIGNWLGAINNWVTLQEQYETFLCVVDLHAITASYNPKELSKN
CCHHHHHCCCCCCCCEEHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
TFSTAALYVACGIDPNICSIFVQSQISAHSELCWILNCMTPINWMERMIQFKEKSIQQGN
HHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
NVSIGLFDYPILMAADILLYDADFVPVGEDQKQHLELARDIAQQRINARFSKDKNILKIP
CEEEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
QPIIMKNGSKIMSLIDGSKKMSKSDPNEGSRINLLDPPEIITKKIKRAKSDSSIGIEFNN
CHHHHCCCHHHHHHHCCCHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCEEEEECC
PERPESKNLMMIYSILSGKEISQCENEFLETGWGTFKKLITEQLIESLEPIQKKYKLLMN
CCCCCCCCEEEEEEHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPYQLSKILNEGKEKAEDLANQTLKRVKSKLGFFEMEK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]