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The map label for this gene is frr [H]

Identifier: 126695885

GI number: 126695885

Start: 477351

End: 477872

Strand: Reverse

Name: frr [H]

Synonym: P9301_05471

Alternate gene names: 126695885

Gene position: 477872-477351 (Counterclockwise)

Preceding gene: 126695886

Following gene: 126695884

Centisome position: 29.11

GC content: 31.8

Gene sequence:

>522_bases
ATGAATAAAAGTATTGAAGCCACTCAAAGAAACTTTAATACAATTAGGACTGGCAGAGCTAATGCTTCATTGCTAGACAG
AGTAAGTGTTGAGTATTATGGAGCAGAAACACCAATTAAATCACTTGCCACAATAAGCACTGTTGACTCACAAACGATTT
CAATACAACCATTTGATATTTCATGTTTACAAGCGATTGAGAAATCTATTTCCATGAGTGATTTAGGTATTACTCCAAAT
AACGATGGTAAAGTAATAAGAATAAATGTTCCTCCCTTAACAGAGGAAAGAAGAAAAGAATTCTGTAAATTGGCCTCTAA
ATATGCAGAGGAAGGGAAAGTAGCTTTGAGAAATATCAGAAGAGATGCTGTTGATAAAGAGAAAAAAGACGAAAAAGATG
GTCTTATTTCAATTGACGAATCGAGAGATAATCAATCTGAAATTCAGAAAATTACTGATAAATATATTGCCTTAATAGAA
ACTAAATTGTCTGAAAAAGAAAAGGAAATTCTAAAAGTTTGA

Upstream 100 bases:

>100_bases
AACATTTCTAAAGCTGTTGATGGGGATCCTATAGGTTCATTAATTAGTTAAAGCTTATTTAATTTTTTTTATTATGAAAG
AACAAGAAATTCAAGAAAAT

Downstream 100 bases:

>100_bases
TCGGATTTGACGTCGTAATAATTGGTGGAGGTTTATCAGGATCTTCCACCGCTCTTAACCTATCAAAGAAAGGATATTCA
GTTTTAATTATCGAGAAAGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDISCLQAIEKSISMSDLGITPN
NDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKITDKYIALIE
TKLSEKEKEILKV

Sequences:

>Translated_173_residues
MNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDISCLQAIEKSISMSDLGITPN
NDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKITDKYIALIE
TKLSEKEKEILKV
>Mature_173_residues
MNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDISCLQAIEKSISMSDLGITPN
NDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAVDKEKKDEKDGLISIDESRDNQSEIQKITDKYIALIE
TKLSEKEKEILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=172, Percent_Identity=29.6511627906977, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1786368, Length=172, Percent_Identity=48.8372093023256, Blast_Score=164, Evalue=3e-42,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 19507; Mature: 19507

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDI
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHCCCCEEEECCCCH
SCLQAIEKSISMSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIR
HHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAVDKEKKDEKDGLISIDESRDNQSEIQKITDKYIALIETKLSEKEKEILKV
HHHHCHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKSIEATQRNFNTIRTGRANASLLDRVSVEYYGAETPIKSLATISTVDSQTISIQPFDI
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHCCCCEEEECCCCH
SCLQAIEKSISMSDLGITPNNDGKVIRINVPPLTEERRKEFCKLASKYAEEGKVALRNIR
HHHHHHHHHCCHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAVDKEKKDEKDGLISIDESRDNQSEIQKITDKYIALIETKLSEKEKEILKV
HHHHCHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA