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The map label for this gene is ubiA [H]

Identifier: 126695819

GI number: 126695819

Start: 420638

End: 421546

Strand: Reverse

Name: ubiA [H]

Synonym: P9301_04811

Alternate gene names: 126695819

Gene position: 421546-420638 (Counterclockwise)

Preceding gene: 126695821

Following gene: 126695818

Centisome position: 25.67

GC content: 31.46

Gene sequence:

>909_bases
ATGAAATATACAATAGATCATATGCAAAACAAAAATCGACAAATTAAATTAAGTACTTTTTTTGAATTATTAAGGTGGAA
TAAGCCGACTGGCAGAATGATCTTACTTATTCCTGCTGGATGGAGTTTATATTTAACCCCAGAAGCAAATCCAAAATTTT
TAATGTTGCTAAGAATAATACTGGGAGGACTACTAGTAAGTGGATTAGGCTGCGTGGTTAACGATATTTGGGACAAAAAA
ATTGATCAAAGAGTTGTTAGGACAAAAAATAGACCTCTAGCTGCAAATAAAATCGGTCTTAAAACAGCTTATTCAATTCT
TTTCTTTTTAATTTTATGTAGCTTCTTTTTAACTTTGTCACTACCTCAGCCTGGAAGAACCCTTTCTATTTCACTTGCTT
TTGTAGCTTTACCAATTATCTTAATTTATCCTTCTGCCAAAAGATGGTTTAAATATCCTCAATTAATCTTATCCATATGC
TGGGGTTTTGCAGTCTTAATTCCCTGGGCCGCAAATGAAGGCAATTTAAATAGTATTGTTTTATTATTTTGCTGGCTAGC
TACCATTTTTTGGACTTTTGGCTTCGACACGATTTATGCTTTAGCAGATAAAAAATATGATATCAAAATTGGAATAAATA
GTTCCGCTGTTAACCTCCAGAACAATACAAGAATAACTATTCAAATTTGCTATTTTTTAACTTCTTGTTTTCTCGCATTA
TGCGGATTTATTAATCAAATGGATTTTATTTTTTGGCCAATTTGGCTTACAACGTCAATCTTAATGCAGAGAGATATACT
GAAAGTATTTCCTGAGGAAAAGCAATCAATAAAAAATATTGGGAATCACTTCAAAAATCAATCAATTTATGGAGGGGTCC
TTTTATTAGGAATTATTATTGCCTCATAA

Upstream 100 bases:

>100_bases
TTTTATAAGACGAAGATATCTTTAATCCATTAATAAATATACCCAACATTGATTATTAAATAATAGAAATCATTTAATCC
TAGTAAGATTATTTAAAGTT

Downstream 100 bases:

>100_bases
ATTCTAAATATGTTTTTTAGATTAAAAAAAGGAGATCTAATAGATATTTTAGCTCCGGGCTCCTTTATTGATGAAGACGA
AAATTTTCAAAAAGGTATAG

Product: prenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKYTIDHMQNKNRQIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPEANPKFLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQRVVRTKNRPLAANKIGLKTAYSILFFLILCSFFLTLSLPQPGRTLSISLAFVALPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSCFLAL
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAS

Sequences:

>Translated_302_residues
MKYTIDHMQNKNRQIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPEANPKFLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQRVVRTKNRPLAANKIGLKTAYSILFFLILCSFFLTLSLPQPGRTLSISLAFVALPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSCFLAL
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAS
>Mature_302_residues
MKYTIDHMQNKNRQIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPEANPKFLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQRVVRTKNRPLAANKIGLKTAYSILFFLILCSFFLTLSLPQPGRTLSISLAFVALPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSCFLAL
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=231, Percent_Identity=32.034632034632, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1790473, Length=298, Percent_Identity=32.2147651006711, Blast_Score=137, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17553718, Length=288, Percent_Identity=30.2083333333333, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32565247, Length=289, Percent_Identity=30.7958477508651, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17553720, Length=345, Percent_Identity=26.3768115942029, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32565245, Length=143, Percent_Identity=34.2657342657343, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32565243, Length=143, Percent_Identity=34.2657342657343, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324370, Length=228, Percent_Identity=32.0175438596491, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21355567, Length=285, Percent_Identity=28.0701754385965, Blast_Score=127, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34517; Mature: 34517

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTIDHMQNKNRQIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPEANPKFLMLLRII
CCEEHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHH
LGGLLVSGLGCVVNDIWDKKIDQRVVRTKNRPLAANKIGLKTAYSILFFLILCSFFLTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
LPQPGRTLSISLAFVALPIILIYPSAKRWFKYPQLILSICWGFAVLIPWAANEGNLNSIV
CCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSCFLAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEEEHHHHHHHHHHHH
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIII
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AS
CC
>Mature Secondary Structure
MKYTIDHMQNKNRQIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPEANPKFLMLLRII
CCEEHHHHCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHH
LGGLLVSGLGCVVNDIWDKKIDQRVVRTKNRPLAANKIGLKTAYSILFFLILCSFFLTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
LPQPGRTLSISLAFVALPIILIYPSAKRWFKYPQLILSICWGFAVLIPWAANEGNLNSIV
CCCCCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSCFLAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEEEHHHHHHHHHHHH
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIII
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA