BacMap

Definition	Burkholderia mallei NCTC 10247 chromosome II, complete genome.
Accession	NC_009079
Length	2,352,693

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The map label for this gene is ucpA [C]

Identifier: 126447398

GI number: 126447398

Start: 2210057

End: 2210812

Strand: Reverse

Name: ucpA [C]

Synonym: BMA10247_A2278

Alternate gene names: 126447398

Gene position: 2210812-2210057 (Counterclockwise)

Preceding gene: 126446881

Following gene: 126445622

Centisome position: 93.97

GC content: 72.09

Gene sequence:

>756_bases
GTGTCCCAGCTATCCTCCGATCCAATCTCCGGCGCGTCGCTCGCCGGCCGGACCGCGTTCGTCACGGGCGGCGGGCGCGG
CCTCGGTGCCGCGATCTGCGGCGAGCTCGCGCGCGCCGGCGCGCACGTCGTCGTCGCCGATCTCGACGAAGCGCGCGCGC
GCGGCGTCGCCGAGCGGCTTGCGCGGGACGGCGCGCGCGCGGTGCCGCTCGGCGTCGACGTCGGCGACGAGACGTCGGTG
CGCCACGCATTCGACGCGGCGCGCGAATCGCTCGGCGACATCGACGTGATCGTCAACAACGCGGCGATCGACGTGACGGC
CGCGATCGACGACGTGAGCGTCGACGCCTGGCGGCAGGTGCTGACGACGAACCTGTTCGGGCCGTACCTGCTGTGTCACG
CCGCCGTGCCGATGATGAAGGCGCGCGGCCGCGGGCACATCGTCAACATCGCGTCGACCGCGGCCAAGCGCGCGTGGCCG
AATGCGTCCGCGTATCACGCGACGAAGTGGGGGCTGCTCGGCCTGTCGCATGCATTGCACGCGGAGCTGCGCCCGTCGGG
CGTGCATGTGTCGGCGATCGTCGCGGGCGGCATGCGCACGCCGTTCCTGCTCGATCGCTTTCCCGACATCGACGCCGATA
CGTTGCAGCCGCCCGAGCACGTCGCGGCGGCCGTGCGCTTCGTGCTCACGCAGCCGCCGGGCACGGTGATTCCCGAGGTG
ATGGTGCTGCCCGTGAAGGAAACGTCATGGCCGTGA

Upstream 100 bases:

>100_bases
GCTCGCGCCGCGCCGGGCACGCAAATCGCTGGAAGGGGAACGCAGCCGCTTGTCTCGGCAAGCATTCGATTCCTCGACTC
ACAGGACTCAAGGAGCGCAC

Downstream 100 bases:

>100_bases
CCGACGCGCGCGCGGCGCCGTGCTGCTCGACAAGGACGGCACGCTGCTCGAAAACGTGCCGTACAACGTCGATCCCGCGC
GGATGCGGCTCGCGCGCGGC

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSQLSSDPISGASLAGRTAFVTGGGRGLGAAICGELARAGAHVVVADLDEARARGVAERLARDGARAVPLGVDVGDETSV
RHAFDAARESLGDIDVIVNNAAIDVTAAIDDVSVDAWRQVLTTNLFGPYLLCHAAVPMMKARGRGHIVNIASTAAKRAWP
NASAYHATKWGLLGLSHALHAELRPSGVHVSAIVAGGMRTPFLLDRFPDIDADTLQPPEHVAAAVRFVLTQPPGTVIPEV
MVLPVKETSWP

Sequences:

>Translated_251_residues
MSQLSSDPISGASLAGRTAFVTGGGRGLGAAICGELARAGAHVVVADLDEARARGVAERLARDGARAVPLGVDVGDETSV
RHAFDAARESLGDIDVIVNNAAIDVTAAIDDVSVDAWRQVLTTNLFGPYLLCHAAVPMMKARGRGHIVNIASTAAKRAWP
NASAYHATKWGLLGLSHALHAELRPSGVHVSAIVAGGMRTPFLLDRFPDIDADTLQPPEHVAAAVRFVLTQPPGTVIPEV
MVLPVKETSWP
>Mature_250_residues
SQLSSDPISGASLAGRTAFVTGGGRGLGAAICGELARAGAHVVVADLDEARARGVAERLARDGARAVPLGVDVGDETSVR
HAFDAARESLGDIDVIVNNAAIDVTAAIDDVSVDAWRQVLTTNLFGPYLLCHAAVPMMKARGRGHIVNIASTAAKRAWPN
ASAYHATKWGLLGLSHALHAELRPSGVHVSAIVAGGMRTPFLLDRFPDIDADTLQPPEHVAAAVRFVLTQPPGTVIPEVM
VLPVKETSWP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=30.2904564315353, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI19923817, Length=235, Percent_Identity=29.3617021276596, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI109715829, Length=253, Percent_Identity=30.0395256916996, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=28.2608695652174, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=31.0526315789474, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=31.0526315789474, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=32.0441988950276, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI20149619, Length=222, Percent_Identity=29.2792792792793, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI40254992, Length=221, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI15277342, Length=235, Percent_Identity=28.936170212766, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=29.4820717131474, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI210032110, Length=198, Percent_Identity=24.2424242424242, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI40254986, Length=184, Percent_Identity=31.5217391304348, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI142976729, Length=234, Percent_Identity=23.9316239316239, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4504505, Length=222, Percent_Identity=33.7837837837838, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=31.1004784688995, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4502601, Length=153, Percent_Identity=35.2941176470588, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI44680136, Length=228, Percent_Identity=26.7543859649123, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI44680133, Length=228, Percent_Identity=26.7543859649123, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI17738292, Length=228, Percent_Identity=26.7543859649123, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI7657478, Length=213, Percent_Identity=29.1079812206573, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI59889578, Length=168, Percent_Identity=30.3571428571429, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI32455239, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031765, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI223718074, Length=200, Percent_Identity=32, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226371731, Length=194, Percent_Identity=29.8969072164948, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4502599, Length=154, Percent_Identity=32.4675324675325, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI83715985, Length=189, Percent_Identity=30.1587301587302, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=36.8932038834951, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31542939, Length=231, Percent_Identity=26.4069264069264, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI10190704, Length=184, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI126723750, Length=193, Percent_Identity=29.5336787564767, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI157739938, Length=196, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI209862901, Length=215, Percent_Identity=28.3720930232558, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI19923983, Length=215, Percent_Identity=28.3720930232558, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI25282469, Length=269, Percent_Identity=23.0483271375465, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI40548397, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010158, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010156, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22758144, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=35.0785340314136, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=27.8481012658228, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=31.9148936170213, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=27.1276595744681, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=192, Percent_Identity=30.2083333333333, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789057, Length=210, Percent_Identity=30.4761904761905, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786701, Length=260, Percent_Identity=28.4615384615385, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787905, Length=226, Percent_Identity=28.7610619469027, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789208, Length=214, Percent_Identity=28.5046728971963, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787820, Length=241, Percent_Identity=27.8008298755187, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367175, Length=233, Percent_Identity=29.1845493562232, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786812, Length=190, Percent_Identity=27.3684210526316, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=30.3664921465969, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=224, Percent_Identity=31.6964285714286, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=27.0408163265306, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17564282, Length=243, Percent_Identity=24.6913580246914, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=210, Percent_Identity=31.9047619047619, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17558628, Length=190, Percent_Identity=32.1052631578947, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=171, Percent_Identity=27.4853801169591, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=28.2786885245902, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=168, Percent_Identity=27.9761904761905, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=209, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17507613, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=215, Percent_Identity=29.7674418604651, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=225, Percent_Identity=27.5555555555556, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534660, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=227, Percent_Identity=29.9559471365639, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=251, Percent_Identity=24.7011952191235, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=197, Percent_Identity=26.3959390862944, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=208, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=175, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=254, Percent_Identity=24.0157480314961, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=219, Percent_Identity=26.9406392694064, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=32.8205128205128, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641232, Length=244, Percent_Identity=30.327868852459, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21358495, Length=246, Percent_Identity=28.0487804878049, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI116007236, Length=243, Percent_Identity=30.8641975308642, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571526, Length=186, Percent_Identity=31.1827956989247, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355631, Length=242, Percent_Identity=31.404958677686, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=25.4166666666667, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281364892, Length=178, Percent_Identity=30.8988764044944, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=29.3193717277487, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644339, Length=185, Percent_Identity=28.6486486486486, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281364494, Length=245, Percent_Identity=28.9795918367347, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17737361, Length=197, Percent_Identity=29.9492385786802, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=227, Percent_Identity=29.0748898678414, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356301, Length=194, Percent_Identity=29.8969072164948, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=31.1827956989247, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI23397609, Length=181, Percent_Identity=30.939226519337, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28571387, Length=242, Percent_Identity=27.6859504132231, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649181, Length=192, Percent_Identity=28.6458333333333, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=28.4153005464481, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641388, Length=249, Percent_Identity=30.1204819277108, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=28.4153005464481, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI18859837, Length=213, Percent_Identity=31.924882629108, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584748, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161076933, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007234, Length=242, Percent_Identity=28.5123966942149, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643142, Length=183, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584752, Length=181, Percent_Identity=28.1767955801105, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581726, Length=175, Percent_Identity=26.2857142857143, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24663911, Length=246, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24665243, Length=214, Percent_Identity=27.1028037383178, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI221331218, Length=210, Percent_Identity=27.6190476190476, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26222; Mature: 26091

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLSSDPISGASLAGRTAFVTGGGRGLGAAICGELARAGAHVVVADLDEARARGVAERL
CCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
ARDGARAVPLGVDVGDETSVRHAFDAARESLGDIDVIVNNAAIDVTAAIDDVSVDAWRQV
HHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCEEEEEEECCCCCHHHHHHH
LTTNLFGPYLLCHAAVPMMKARGRGHIVNIASTAAKRAWPNASAYHATKWGLLGLSHALH
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AELRPSGVHVSAIVAGGMRTPFLLDRFPDIDADTLQPPEHVAAAVRFVLTQPPGTVIPEV
CCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
MVLPVKETSWP
EEEECCCCCCC
>Mature Secondary Structure 
SQLSSDPISGASLAGRTAFVTGGGRGLGAAICGELARAGAHVVVADLDEARARGVAERL
CCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHH
ARDGARAVPLGVDVGDETSVRHAFDAARESLGDIDVIVNNAAIDVTAAIDDVSVDAWRQV
HHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCEEEEEEECCCCCHHHHHHH
LTTNLFGPYLLCHAAVPMMKARGRGHIVNIASTAAKRAWPNASAYHATKWGLLGLSHALH
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AELRPSGVHVSAIVAGGMRTPFLLDRFPDIDADTLQPPEHVAAAVRFVLTQPPGTVIPEV
CCCCCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
MVLPVKETSWP
EEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]