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The map label for this gene is accB [H]

Identifier: 126446269

GI number: 126446269

Start: 2090196

End: 2090438

Strand: Direct

Name: accB [H]

Synonym: BMA10247_A2157

Alternate gene names: 126446269

Gene position: 2090196-2090438 (Clockwise)

Preceding gene: 126446983

Following gene: 126447049

Centisome position: 88.84

GC content: 69.55

Gene sequence:

>243_bases
ATGGCACAACACGAAATCGTCAGCCCGCTGCCCGGGACGTTCTACCGGCGCCCGTCGCCCGACGCGGCTCCTTTCGTCGA
CGTCGGCTCGACGCTCGCGCCCGGCGCGGTGGTCGGGATCGTCGAAGTGATGAAGCAGTTCACCGAGATCGAGACGGCGG
CCGCGGGCCGCGTCGTCGAGATTCTGGTCGACGACGGCGAGCCCGTCGACGCGGGCCAGGTGCTGATGCGCACGGAGGAG
TGA

Upstream 100 bases:

>100_bases
ACCCGCGATGCGCTCACCGCGCACGGCATCCGCATCGCCGCGCCGGCGACGGCCGAGGCCAACGGAATTCGTATCGATGA
AGCTTGAGGATCCCCACGAG

Downstream 100 bases:

>100_bases
GCGCGATGAACGACCTCGATTCGACCCACGCTTCGTTTTACCGGCCGTCCCGGATCGGTACGGTGCTCGTCGCCAATCGC
GGCGAGATCGCGGTGCGCGT

Product: hypothetical protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MAQHEIVSPLPGTFYRRPSPDAAPFVDVGSTLAPGAVVGIVEVMKQFTEIETAAAGRVVEILVDDGEPVDAGQVLMRTEE

Sequences:

>Translated_80_residues
MAQHEIVSPLPGTFYRRPSPDAAPFVDVGSTLAPGAVVGIVEVMKQFTEIETAAAGRVVEILVDDGEPVDAGQVLMRTEE
>Mature_79_residues
AQHEIVSPLPGTFYRRPSPDAAPFVDVGSTLAPGAVVGIVEVMKQFTEIETAAAGRVVEILVDDGEPVDAGQVLMRTEE

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=67, Percent_Identity=47.7611940298507, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 8480; Mature: 8349

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQHEIVSPLPGTFYRRPSPDAAPFVDVGSTLAPGAVVGIVEVMKQFTEIETAAAGRVVE
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
ILVDDGEPVDAGQVLMRTEE
EEECCCCCCCCCCEEEECCC
>Mature Secondary Structure 
AQHEIVSPLPGTFYRRPSPDAAPFVDVGSTLAPGAVVGIVEVMKQFTEIETAAAGRVVE
CCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
ILVDDGEPVDAGQVLMRTEE
EEECCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592499; 8969508; 9384377 [H]