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The map label for this gene is kdgR [H]

Identifier: 126442953

GI number: 126442953

Start: 453365

End: 454132

Strand: Reverse

Name: kdgR [H]

Synonym: BURPS668_A0497

Alternate gene names: 126442953

Gene position: 454132-453365 (Counterclockwise)

Preceding gene: 126443886

Following gene: 126442981

Centisome position: 14.52

GC content: 71.48

Gene sequence:

>768_bases
ATGAACTACATCGTCGACGCGGTCGACAGCGCGCTGAAGCTGTTGAGCTTCGTGGCCGAGCATCCGCACCTCGGCGTGAC
CGAGCTCGCGTCGAAGCTCGGCATCAACAAGTCGCGCACGTACCGGATGCTGTGCACGCTCGAGCTGCACCGCTTCGTCG
TGCAGGACGCGCGCACGTCGACCTACGCGCTCGGGCCGCAGGCGTTCGTGATCGGCGTCGCGGCGGCCCAGCAGAACGCG
CTCGTGCGCGCCGCGCAGCGCCACATGCTCGCGCTCAGCCAGGCGATCAACGAGACCGTCGTGCTGCGCGTGCGCGAAGG
GCTCGAGACGGTCTGCGTCGCGCGCTGCGAGACGACGCACGAGATCCGCACGATCGGCTCGGTCGGCAACCGCCGGCCGG
TCGGCCTCGGCGCGTCGGGCAAGGTGCTGCTCGCGTTCGCGCCCGACGCGGTGCGCAACGAGTATTTCGCGCGCGTGCGC
AAGGCCGCGCAGGGCGATCCGCTGCGGCTCGTCGAGGAGCTCGACGCGATCTCGCGCAAGGGCTACGCGGTGAGCGTCGG
CGAGGTGACGGCGGGCGCGGTCGCGATCGCGGTGCCGGTGCGCGACCTGACGGGCGAGACGCTCGCTTCGGTCAGCGTGG
CGGGGCCGGAGATGCGGATCAGCCGCGTCGAGATTCCCGACTACCTCGAGCGGCTGCAAGCCTGCAGCCACGCGATCTCC
GCCGAACTCGGCTACGTCCCGGCGCGCGCCGCGCCGCAACCCGCATGA

Upstream 100 bases:

>100_bases
GCTTCGCGGCGCTCAAGCGCACCGTCGACGCGTATCTCGACGCGCTCGCCGCCCACGTGCGCGCGCAACTGCCGCCGCCG
CGCGGCGAAGGAGTCTCGCG

Downstream 100 bases:

>100_bases
AAGCCCGCTCCCCCGCCATGCTCGCCGCGCCCGCGCATTGCGCCGACACGCCTCGAACGCCCGATATGCCCGATATGCCC
GATATGCCCGACACGCGCGG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNYIVDAVDSALKLLSFVAEHPHLGVTELASKLGINKSRTYRMLCTLELHRFVVQDARTSTYALGPQAFVIGVAAAQQNA
LVRAAQRHMLALSQAINETVVLRVREGLETVCVARCETTHEIRTIGSVGNRRPVGLGASGKVLLAFAPDAVRNEYFARVR
KAAQGDPLRLVEELDAISRKGYAVSVGEVTAGAVAIAVPVRDLTGETLASVSVAGPEMRISRVEIPDYLERLQACSHAIS
AELGYVPARAAPQPA

Sequences:

>Translated_255_residues
MNYIVDAVDSALKLLSFVAEHPHLGVTELASKLGINKSRTYRMLCTLELHRFVVQDARTSTYALGPQAFVIGVAAAQQNA
LVRAAQRHMLALSQAINETVVLRVREGLETVCVARCETTHEIRTIGSVGNRRPVGLGASGKVLLAFAPDAVRNEYFARVR
KAAQGDPLRLVEELDAISRKGYAVSVGEVTAGAVAIAVPVRDLTGETLASVSVAGPEMRISRVEIPDYLERLQACSHAIS
AELGYVPARAAPQPA
>Mature_255_residues
MNYIVDAVDSALKLLSFVAEHPHLGVTELASKLGINKSRTYRMLCTLELHRFVVQDARTSTYALGPQAFVIGVAAAQQNA
LVRAAQRHMLALSQAINETVVLRVREGLETVCVARCETTHEIRTIGSVGNRRPVGLGASGKVLLAFAPDAVRNEYFARVR
KAAQGDPLRLVEELDAISRKGYAVSVGEVTAGAVAIAVPVRDLTGETLASVSVAGPEMRISRVEIPDYLERLQACSHAIS
AELGYVPARAAPQPA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=249, Percent_Identity=30.9236947791165, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786468, Length=253, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082359, Length=232, Percent_Identity=26.2931034482759, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789999, Length=248, Percent_Identity=28.2258064516129, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786715, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790752, Length=244, Percent_Identity=25.8196721311475, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27336; Mature: 27336

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIVDAVDSALKLLSFVAEHPHLGVTELASKLGINKSRTYRMLCTLELHRFVVQDARTS
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCC
TYALGPQAFVIGVAAAQQNALVRAAQRHMLALSQAINETVVLRVREGLETVCVARCETTH
EEEECCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
EIRTIGSVGNRRPVGLGASGKVLLAFAPDAVRNEYFARVRKAAQGDPLRLVEELDAISRK
HHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GYAVSVGEVTAGAVAIAVPVRDLTGETLASVSVAGPEMRISRVEIPDYLERLQACSHAIS
CCEEEECCCCCCEEEEEEECHHCCCHHHHHEEECCCCEEEEEECCHHHHHHHHHHHHHHH
AELGYVPARAAPQPA
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MNYIVDAVDSALKLLSFVAEHPHLGVTELASKLGINKSRTYRMLCTLELHRFVVQDARTS
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCC
TYALGPQAFVIGVAAAQQNALVRAAQRHMLALSQAINETVVLRVREGLETVCVARCETTH
EEEECCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHH
EIRTIGSVGNRRPVGLGASGKVLLAFAPDAVRNEYFARVRKAAQGDPLRLVEELDAISRK
HHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GYAVSVGEVTAGAVAIAVPVRDLTGETLASVSVAGPEMRISRVEIPDYLERLQACSHAIS
CCEEEECCCCCCEEEEEEECHHCCCHHHHHEEECCCCEEEEEECCHHHHHHHHHHHHHHH
AELGYVPARAAPQPA
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]