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The map label for this gene is narQ [H]

Identifier: 126207946

GI number: 126207946

Start: 533862

End: 535577

Strand: Direct

Name: narQ [H]

Synonym: APL_0462

Alternate gene names: 126207946

Gene position: 533862-535577 (Clockwise)

Preceding gene: 126207945

Following gene: 126207947

Centisome position: 23.47

GC content: 40.85

Gene sequence:

>1716_bases
ATGAATAAACCGGTTAATTATTCTAAATATTCCATCGCTCGTCGTATCGGATTCTATTTTCTGGTGATGATTGCTTTTGC
CTCTTTAATCAGCGGCATTTCACTCAGTATTATGTGGAGTAATAAATCGGATGCGGGGCTGATTAATGTCTCCGGTTCGT
TGCGAATGCAGAGTTACCGTTTTCTTTATGAAATGGAACATCATCCGCAATCTATTCCGGCTCGTCTAGCCGAATATCGC
CAAAGTTTAAATTCGCCGGAGATTCAAAACTCTTTAGAACATAAGTGTTTATTGCCGAAAGAGGTTACGGAGGCTTATGC
CAAGTTGCAAAAAAACTGGCTGGAAATGGAGTCTTTTATCGTTAAGCGGGATAGAAACGCCTATGAAGCCAACATAGAAG
GCTATGCGAATCAAGTGAATAATTTTGTTTGGCAGTTACAGGAATTTGTCGAACTGAAATTAAAAGTGGCAATCGGCGTA
ATTGCCGTGTCGATGTTACTGATTATTGCGTTAGCCTATTTCGGCGTATGGTACACCCGTAAACGTATTATTACTCCGCT
TAATCAATTGGTCACGGCAAGCCGACAAGTGAAAAACGAAGATTTTGATCATATCCGATTGGCGGTGGACGATCCTAACG
AACTCGGTCTTCTTTCGTCCGCTTTTACGCAGATGGCAAGCGAGCTGGCTAAACTTTACGCTTCTTTGGAAGAAAAAGTG
GAAGATAAAACGCGACGTTTAATGGCGGTTAATCGCTCGTTATTGGTACTTTTCCAATGTTCTCAATTACTAACCGCCAA
ACCGGTCAATCAAAGCGTACTATTTAAAGTATTACAAACGATTTTGGATAACGAACAATTACGCGGTATCGAAATTCAGG
TCTATGGTGCGGATTATTGGAACGTAACTATTGATAATGCGCCGGAACAAGATTGGCAGTTTAATGAAATTGCAATTGAA
AATGAAAAACTGGCTTTATTACGTTGGAAACCGTCATTACTTTGTCCGGATGAACGCCTAATTCAAAACGTATCGGAAAT
GATCGGACGTAGTCTTTATGTATTGCAGGTACAAAAGCAGCAACAACAATTGCTGTTAATGGAAGAACGTTCGATTATTG
CACGAGAGCTGCACGATTCGCTGGCACAATCTTTAACTTTTTTCAAAATTCAAGTCAGTTTATTAAAACGTAACGGCGAA
GTTAAACAGGATTGGGATAAACAAAAAGCAATTTTAAATGATTTTGAAAAAGCCTTAAATGAAGCTTATAGCCAATTGCG
TGAGTTACTTTCAACCTTTCGCTTAACCATTGAAGAAGCGAATCTGACCCATGCGTTAGAACGAGTATTGGATTCGTTAC
GCATTCGAACATCGGCTCAAATTCGTCTGAATTGTAAATTGCCTTCGCAAATTTTTAGTGCGCAGCAACAAGTTCATGCG
TTACAGATTGTGCGTGAGGCGGTGATTAATGCGATTAAACATGCTAATGCAACGGAAATCTATGTGGTGGCGGAAACCAA
TGCCGATGGTGAACATTGCTTAATTATTCGTGACAACGGCAAGGGGATTGCAAGCGATATTGAGCCGGAAGGGCATTACG
GGCTGACAATCATGAAAGAACGCGCGGCGGAATTAAAAGGCGAATTCAGTATTAAAAACCGTCCGGAAGGCGGTGTTGAA
GTAGTGGTCGTATTACCGAATATGATTACCGCATAA

Upstream 100 bases:

>100_bases
GGGATTCGGAAGAAGAAGTCAAGCAGCGCGCCGATAAAACCATCGGTTCCAATAGTGAAGACAGTATTGCGAAAACATTA
ACGGAATTACTTAATTTATA

Downstream 100 bases:

>100_bases
TTTTTATAAAGGAAGGCACTAAATGCAGATTCGAAAATCGACGGAAGCGGATTTCGAAACAATTTTAAATATTTATAACC
AAGCGATTCCGACTCATCAA

Product: nitrate/nitrite sensor protein NarQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MNKPVNYSKYSIARRIGFYFLVMIAFASLISGISLSIMWSNKSDAGLINVSGSLRMQSYRFLYEMEHHPQSIPARLAEYR
QSLNSPEIQNSLEHKCLLPKEVTEAYAKLQKNWLEMESFIVKRDRNAYEANIEGYANQVNNFVWQLQEFVELKLKVAIGV
IAVSMLLIIALAYFGVWYTRKRIITPLNQLVTASRQVKNEDFDHIRLAVDDPNELGLLSSAFTQMASELAKLYASLEEKV
EDKTRRLMAVNRSLLVLFQCSQLLTAKPVNQSVLFKVLQTILDNEQLRGIEIQVYGADYWNVTIDNAPEQDWQFNEIAIE
NEKLALLRWKPSLLCPDERLIQNVSEMIGRSLYVLQVQKQQQQLLLMEERSIIARELHDSLAQSLTFFKIQVSLLKRNGE
VKQDWDKQKAILNDFEKALNEAYSQLRELLSTFRLTIEEANLTHALERVLDSLRIRTSAQIRLNCKLPSQIFSAQQQVHA
LQIVREAVINAIKHANATEIYVVAETNADGEHCLIIRDNGKGIASDIEPEGHYGLTIMKERAAELKGEFSIKNRPEGGVE
VVVVLPNMITA

Sequences:

>Translated_571_residues
MNKPVNYSKYSIARRIGFYFLVMIAFASLISGISLSIMWSNKSDAGLINVSGSLRMQSYRFLYEMEHHPQSIPARLAEYR
QSLNSPEIQNSLEHKCLLPKEVTEAYAKLQKNWLEMESFIVKRDRNAYEANIEGYANQVNNFVWQLQEFVELKLKVAIGV
IAVSMLLIIALAYFGVWYTRKRIITPLNQLVTASRQVKNEDFDHIRLAVDDPNELGLLSSAFTQMASELAKLYASLEEKV
EDKTRRLMAVNRSLLVLFQCSQLLTAKPVNQSVLFKVLQTILDNEQLRGIEIQVYGADYWNVTIDNAPEQDWQFNEIAIE
NEKLALLRWKPSLLCPDERLIQNVSEMIGRSLYVLQVQKQQQQLLLMEERSIIARELHDSLAQSLTFFKIQVSLLKRNGE
VKQDWDKQKAILNDFEKALNEAYSQLRELLSTFRLTIEEANLTHALERVLDSLRIRTSAQIRLNCKLPSQIFSAQQQVHA
LQIVREAVINAIKHANATEIYVVAETNADGEHCLIIRDNGKGIASDIEPEGHYGLTIMKERAAELKGEFSIKNRPEGGVE
VVVVLPNMITA
>Mature_571_residues
MNKPVNYSKYSIARRIGFYFLVMIAFASLISGISLSIMWSNKSDAGLINVSGSLRMQSYRFLYEMEHHPQSIPARLAEYR
QSLNSPEIQNSLEHKCLLPKEVTEAYAKLQKNWLEMESFIVKRDRNAYEANIEGYANQVNNFVWQLQEFVELKLKVAIGV
IAVSMLLIIALAYFGVWYTRKRIITPLNQLVTASRQVKNEDFDHIRLAVDDPNELGLLSSAFTQMASELAKLYASLEEKV
EDKTRRLMAVNRSLLVLFQCSQLLTAKPVNQSVLFKVLQTILDNEQLRGIEIQVYGADYWNVTIDNAPEQDWQFNEIAIE
NEKLALLRWKPSLLCPDERLIQNVSEMIGRSLYVLQVQKQQQQLLLMEERSIIARELHDSLAQSLTFFKIQVSLLKRNGE
VKQDWDKQKAILNDFEKALNEAYSQLRELLSTFRLTIEEANLTHALERVLDSLRIRTSAQIRLNCKLPSQIFSAQQQVHA
LQIVREAVINAIKHANATEIYVVAETNADGEHCLIIRDNGKGIASDIEPEGHYGLTIMKERAAELKGEFSIKNRPEGGVE
VVVVLPNMITA

Specific function: Probable member of a two-component regulatory system. It is not known what protein it phosphorylates and in which regulatory pathway it acts, as the narL and other nar genes do not exist in H.influenzae [H]

COG id: COG3850

COG function: function code T; Signal transduction histidine kinase, nitrate/nitrite-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=555, Percent_Identity=43.963963963964, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1787474, Length=578, Percent_Identity=29.4117647058824, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR016380
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65288; Mature: 65288

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPVNYSKYSIARRIGFYFLVMIAFASLISGISLSIMWSNKSDAGLINVSGSLRMQSYR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCHHHHHHH
FLYEMEHHPQSIPARLAEYRQSLNSPEIQNSLEHKCLLPKEVTEAYAKLQKNWLEMESFI
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VKRDRNAYEANIEGYANQVNNFVWQLQEFVELKLKVAIGVIAVSMLLIIALAYFGVWYTR
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIITPLNQLVTASRQVKNEDFDHIRLAVDDPNELGLLSSAFTQMASELAKLYASLEEKV
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKTRRLMAVNRSLLVLFQCSQLLTAKPVNQSVLFKVLQTILDNEQLRGIEIQVYGADYW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEE
NVTIDNAPEQDWQFNEIAIENEKLALLRWKPSLLCPDERLIQNVSEMIGRSLYVLQVQKQ
EEEECCCCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEHHH
QQQLLLMEERSIIARELHDSLAQSLTFFKIQVSLLKRNGEVKQDWDKQKAILNDFEKALN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EAYSQLRELLSTFRLTIEEANLTHALERVLDSLRIRTSAQIRLNCKLPSQIFSAQQQVHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
LQIVREAVINAIKHANATEIYVVAETNADGEHCLIIRDNGKGIASDIEPEGHYGLTIMKE
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEHHH
RAAELKGEFSIKNRPEGGVEVVVVLPNMITA
HHHHCCCCCCCCCCCCCCCEEEEECCCHHCC
>Mature Secondary Structure
MNKPVNYSKYSIARRIGFYFLVMIAFASLISGISLSIMWSNKSDAGLINVSGSLRMQSYR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECCCCHHHHHHH
FLYEMEHHPQSIPARLAEYRQSLNSPEIQNSLEHKCLLPKEVTEAYAKLQKNWLEMESFI
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VKRDRNAYEANIEGYANQVNNFVWQLQEFVELKLKVAIGVIAVSMLLIIALAYFGVWYTR
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRIITPLNQLVTASRQVKNEDFDHIRLAVDDPNELGLLSSAFTQMASELAKLYASLEEKV
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EDKTRRLMAVNRSLLVLFQCSQLLTAKPVNQSVLFKVLQTILDNEQLRGIEIQVYGADYW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCEE
NVTIDNAPEQDWQFNEIAIENEKLALLRWKPSLLCPDERLIQNVSEMIGRSLYVLQVQKQ
EEEECCCCCCCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEHHH
QQQLLLMEERSIIARELHDSLAQSLTFFKIQVSLLKRNGEVKQDWDKQKAILNDFEKALN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EAYSQLRELLSTFRLTIEEANLTHALERVLDSLRIRTSAQIRLNCKLPSQIFSAQQQVHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHH
LQIVREAVINAIKHANATEIYVVAETNADGEHCLIIRDNGKGIASDIEPEGHYGLTIMKE
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEHHH
RAAELKGEFSIKNRPEGGVEVVVVLPNMITA
HHHHCCCCCCCCCCCCCCCEEEEECCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]