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The map label for this gene is ybhA [H]

Identifier: 126207945

GI number: 126207945

Start: 533044

End: 533862

Strand: Direct

Name: ybhA [H]

Synonym: APL_0461

Alternate gene names: 126207945

Gene position: 533044-533862 (Clockwise)

Preceding gene: 126207944

Following gene: 126207946

Centisome position: 23.44

GC content: 42.0

Gene sequence:

>819_bases
ATGACCTATCAAGCTATTGCTTTCGATCTCGACGGAACCCTTCTTAATCCCCACGCAACCATTCTCGAATCCAGTAAACA
AGCGATCAAAAAGGCACGTGAAAAAGGTATAAAAGTTTTCTTCGTAACGGGACGTCATCATACGGCCGTTCGCCCGTATT
ATGCGGAAATCGGGTTAGATACGCCGGTAGTGTGTTGTAACGGTACTTATTTATATGATTTTCAGCATGATAAGGTGCTA
TCCGGTAAACCGCTAACGGCGGAGCAAGCCTCTCATCTGATTAATGATGCTAAATCGCAAGGAATTCATACCGCCGTTTA
TTTTCGCGATGCAATGACTTACGAACAACTAAATCCGCATTTTGCAAAATTACAGCAATGGGTTGCTTCTTGCCCAGAAT
CCGTTCGTCCTAACGTTTATCAATTGGAAAGTTTTCAGCAAGAAATCGATAAGGGAACGACGGTTTGGAAAGTGCTGATT
AGTGATCCGAATTTGGAAAAAATGCAAAATTTCGTTAAAAAGTTACCGCTTGATCAATTTAGTCCGGAATGGTCTTGGGT
GGATAGAGTGGATATTACCAGTGTAGGTAATAGTAAAGGCGCAATGTTAGCGGAATTACTGAAAATGGAAGGTCTCGAAC
CGCAAAATGTGATTGCCTTCGGTGATAATTTTAACGATATTTCGATGCTGGAGCTTGTCGGACTCGGCATTGCAATGGGG
GATTCGGAAGAAGAAGTCAAGCAGCGCGCCGATAAAACCATCGGTTCCAATAGTGAAGACAGTATTGCGAAAACATTAAC
GGAATTACTTAATTTATAA

Upstream 100 bases:

>100_bases
ATATAACTCCGGCAAATAATTTACAGTTTCTCTTTAACTGGAGTAAAATAGGGGCTACTTTATAAAGTAGCCTTTTTTAC
GTTTATGCAGGAGAAAATTT

Downstream 100 bases:

>100_bases
TGAATAAACCGGTTAATTATTCTAAATATTCCATCGCTCGTCGTATCGGATTCTATTTTCTGGTGATGATTGCTTTTGCC
TCTTTAATCAGCGGCATTTC

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTYQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLDTPVVCCNGTYLYDFQHDKVL
SGKPLTAEQASHLINDAKSQGIHTAVYFRDAMTYEQLNPHFAKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLI
SDPNLEKMQNFVKKLPLDQFSPEWSWVDRVDITSVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISMLELVGLGIAMG
DSEEEVKQRADKTIGSNSEDSIAKTLTELLNL

Sequences:

>Translated_272_residues
MTYQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLDTPVVCCNGTYLYDFQHDKVL
SGKPLTAEQASHLINDAKSQGIHTAVYFRDAMTYEQLNPHFAKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLI
SDPNLEKMQNFVKKLPLDQFSPEWSWVDRVDITSVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISMLELVGLGIAMG
DSEEEVKQRADKTIGSNSEDSIAKTLTELLNL
>Mature_271_residues
TYQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLDTPVVCCNGTYLYDFQHDKVLS
GKPLTAEQASHLINDAKSQGIHTAVYFRDAMTYEQLNPHFAKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLIS
DPNLEKMQNFVKKLPLDQFSPEWSWVDRVDITSVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISMLELVGLGIAMGD
SEEEVKQRADKTIGSNSEDSIAKTLTELLNL

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=265, Percent_Identity=44.1509433962264, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI48994981, Length=282, Percent_Identity=28.0141843971631, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI2367265, Length=273, Percent_Identity=27.1062271062271, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787043, Length=283, Percent_Identity=26.1484098939929, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 30443; Mature: 30312

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLD
CCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCC
TPVVCCNGTYLYDFQHDKVLSGKPLTAEQASHLINDAKSQGIHTAVYFRDAMTYEQLNPH
CCEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCHH
FAKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLISDPNLEKMQNFVKKLPLDQF
HHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCC
SPEWSWVDRVDITSVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISMLELVGLGIAMG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHEEC
DSEEEVKQRADKTIGSNSEDSIAKTLTELLNL
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYQAIAFDLDGTLLNPHATILESSKQAIKKAREKGIKVFFVTGRHHTAVRPYYAEIGLD
CCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHCCCC
TPVVCCNGTYLYDFQHDKVLSGKPLTAEQASHLINDAKSQGIHTAVYFRDAMTYEQLNPH
CCEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCHH
FAKLQQWVASCPESVRPNVYQLESFQQEIDKGTTVWKVLISDPNLEKMQNFVKKLPLDQF
HHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCC
SPEWSWVDRVDITSVGNSKGAMLAELLKMEGLEPQNVIAFGDNFNDISMLELVGLGIAMG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHEEC
DSEEEVKQRADKTIGSNSEDSIAKTLTELLNL
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503 [H]